Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manisha Arkile"'
Autor:
Vijay M. Khedkar, Dhiman Sarkar, Pankaj B. Miniyar, Ashish S. Kumar, Dattatray D. Anuse, Manisha Arkile, Anand A. Mahajan, Mahesh A. Barmade
Publikováno v:
Letters in Drug Design & Discovery. 16:1264-1275
Background: Treating tuberculosis is a challenge due to the development of drug resistance. Hence, it is imperative to develop novel leads having high potency and efficacy to curb drug resistance. Methods: The present research work is focused on micr
Autor:
Prashant S. Kharkar, Hardik Manek, Dhiman Sarkar, Pradip K. Gadekar, Vijay M. Khedkar, Abhijit Roychowdhury, Vijayaparthasarathi Vijayakumar, Manisha Arkile, S. Sarveswari, Rajiv Sharma
Publikováno v:
European Journal of Medicinal Chemistry. 122:475-487
The design, synthesis and antimicrobial evaluation of a novel series of azaspiro analogues of linezolid (1) have been described. Linezolid comprises of a morpholine ring which is known for its metabolism-related liabilities. Therefore, the key modifi
Publikováno v:
Planta Medica International Open. 3:e55-e59
A bioactivity-guided chemical examination of the acetone extract of the rhizomes of Alpinia galanga led to the isolation of six secondary metabolites, eucalyptol derivative (1) and phenylpropanoids (2–6). The structures of all of the isolated compo
Autor:
Pankaj B. Miniyar, Manisha Arkile, Kalyani D. Asgaonkar, Amar Yeware, Dhiman Sarkar, A. B. Dharme, Vijay M. Khedkar, Prakash C. Jha, Trupti S. Chitre
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:2224-2228
The persistence of Mycobacterium tuberculosis (MTB) in dormant stage assists the pathogen to develop resistance against current antimycobactrial drugs. To address this issue, we report herein the synthesis of N-(4-oxo-2 substituted thiazolidin-3 yl)
Autor:
Manisha Arkile, Laxman Nawale, Utkarsha U. Shedbalkar, Snehal Chopade, Dhiman Sarkar, Sweety A. Wadhwani, Balu A. Chopade, Richa Singh
Publikováno v:
International Journal of Nanomedicine
Richa Singh,1 Laxman Nawale,2 Manisha Arkile,2 Sweety Wadhwani,1 Utkarsha Shedbalkar,1 Snehal Chopade,1 Dhiman Sarkar,2 Balu Ananda Chopade1,3 1Department of Microbiology, Savitribai Phule Pune University, 2Combichem-Bioresource Center, Organic Chemi
Autor:
Amar Yeware, Manisha Arkile, Bapurao B. Shingate, Mubarak H. Shaikh, Dnyaneshwar D. Subhedar, Dhiman Sarkar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:1704-1708
We have developed, highly efficient, one-pot, solvent-free, [Et3NH][HSO4] catalyzed multicomponent reaction protocol for the synthesis of 1,3-thiazolidin-4-ones in excellent yields. For the first time, the 1,3-thiazolidin-4-ones were evaluated in vit
Publikováno v:
Planta Medica Letters. 3:e20-e24
The new 14,15-dinor- cis -labdane diterpene, named (+)-14,15-dinor-9 α -hydroxy- cis -labd-11(E)-en-13-one ( 1 ), was isolated from the acetone extract of the aerial parts of Colebrookea oppositifolia , along with the known compounds alnustin ( 2 ),
Autor:
Mubarak H. Shaikh, Firoz A. Kalam Khan, Dnyaneshwar D. Subhedar, Manisha Arkile, Laxman Nawale, Dhiman Sarkar, Bapurao B. Shingate, Jaiprakash N. Sangshetti
Publikováno v:
Journal of Heterocyclic Chemistry. 54:413-421
A library of 1,2,3-triazoles efficiently prepared via click chemistry and evaluated for their antifungal, antitubercular, antioxidant, cytotoxicity, molecular docking and ADME prediction.
Autor:
Ramrao A. Mane, Manisha Arkile, Lalit D. Khillare, Amarsinh R. Deshmukh, Dhiman Sarkar, Sambhaji T. Dhumal
Publikováno v:
Journal of Heterocyclic Chemistry. 54:125-130
Emergence of multidrug resistant and extensively drug resistant tuberculosis has prompted to develop new molecular entities to treat the disease. A series of new 4-thiazolidinones with pyrazinyl and thiazolyl scaffolds has been synthesized, and their
Autor:
Ashish A. Chinchansure, Anurag Shukla, Swati P. Joshi, Dhiman Sarkar, Manisha Arkile, Dhanasekaran Shanmugam
Publikováno v:
Planta Medica Letters. 2:e35-e38
A phytochemical investigation of the acetone extract from the aerial parts of Leucas mollissima afforded one new (−) epi -marmelo lactone, (2 S , 4 R , 6 S )-2,6-dimethyl-6 hydroxy-7-ene-4-olide ( 1 ), along with five known compounds, schensianol A