Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Manish S. Patankar"'
Autor:
Sejal Sharma, Liping Feng, Nicha Boonpattrawong, Arvinder Kapur, Lisa Barroilhet, Manish S. Patankar, Spencer S. Ericksen
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Focused screening on target-prioritized compound sets can be an efficient alternative to high throughput screening (HTS). For most biomolecular targets, compound prioritization models depend on prior screening data or a target structure. For
Externí odkaz:
https://doaj.org/article/917f8e3cc1944718acb1f5328cb44ee3
Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells
Autor:
Yousef Alharbi, Arvinder Kapur, Mildred Felder, Lisa Barroilhet, Timothy Stein, Bikash R. Pattnaik, Manish S. Patankar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The Na+/K+-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity. The natural product, plumbagin increases
Externí odkaz:
https://doaj.org/article/711cb0ad0da842b3aed61841711db73e
Autor:
Arvinder Kapur, Jose M Ayuso, Shujah Rehman, Santosh Kumari, Mildred Felder, Zach Stenerson, Melisa C Skala, Dave Beebe, Lisa Barroilhet, Manish S Patankar
Publikováno v:
Reproduction. 165:617-628
In brief Developing novel therapies to cure and manage endometriosis is a major unmet need that will benefit over 180 million women worldwide. Results from the current study suggest that inhibitors of oxidative phosphorylation may serve as novel agen
Autor:
Pamela K. Kreeger, Lisa Barroilhet, Paul S. Weisman, Manish S. Patankar, Anne-Sophie Mancha, Harris B. Krause, Harin A. Patel, Kaitlin C. Fogg, Molly J. Carroll
Peritoneal metastasis of high-grade serous ovarian cancer (HGSOC) occurs when tumor cells suspended in ascites adhere to mesothelial cells. Despite the strong relationship between metastatic burden and prognosis in HGSOC, there are currently no thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb08bfd701d72d2fe98550ee75b52ef
https://doi.org/10.1158/0008-5472.c.6510389.v1
https://doi.org/10.1158/0008-5472.c.6510389.v1
Autor:
Pamela K. Kreeger, Lisa Barroilhet, Paul S. Weisman, Manish S. Patankar, Anne-Sophie Mancha, Harris B. Krause, Harin A. Patel, Kaitlin C. Fogg, Molly J. Carroll
Supplemental File contains 8 Figures: SF1 shows a schematic of the co-culture device, SF2 shows additional details of PLSR model and validation of MIP-1β, SF3 shows validation of MIP-1β impact on SELP/P-selectin in mesothelial cell lines, SF4 shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b44891674516555e42874cb90563f3
https://doi.org/10.1158/0008-5472.22419470.v1
https://doi.org/10.1158/0008-5472.22419470.v1
Autor:
Aishwarya Rengarajan, Jason L. Austin, Aleksandar K. Stanic, Manish S. Patankar, Derek S. Boeldt
Publikováno v:
Reproductive Sciences.
Autor:
Mian M K Shahzad, Mildred Felder, Kai Ludwig, Hannah R Van Galder, Matthew L Anderson, Jong Kim, Mark E Cook, Arvinder K Kapur, Manish S Patankar
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189524 (2018)
The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA). MTT assays and QCM™ chemotaxis 96-wells were used to test the effect of t10,c12 CLA on the proliferation and migration and in
Externí odkaz:
https://doaj.org/article/1393d9ac57394cd1afb5e6e5335b6917
Publikováno v:
Acta biomaterialia. 153
Ovarian cancer remains the deadliest of the gynecological cancers, where this arises from poor screening and imaging tools that can detect early disease, and also limited understanding of the structural and functional aspects of the tumor microenviro
Autor:
Roberta Fritz-Klaus, Mark R. Etzel, Rebecca J. Whelan, Saahil Javeri, Manish S. Patankar, Niharika Patankar, Naviya Schuster-Little
Publikováno v:
Analyst
Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) is a desirable goal, because it may enable detection of molecular regions that are not recognized by antibodies and are therefore analytically silent in the cur
Autor:
Germán González, Conor L. Evans, W. Peter Hansen, Jawad Hoballah, Sinyoung Jeong, Fatima Mubarak, Petra B. Krauledat, Lauren A. Austin, Daniel W. Cramer, Arvinder Kapur, Manish S. Patankar, Nicholas H. Nowell, Alexander Ho
Publikováno v:
ACS Sens
Although levels of the circulating ovarian cancer marker (CA125) can distinguish ovarian masses that are likely to be malignant and correlate with severity of disease, serum CA125 has not proved useful in general population screening. Recently, cell