Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Manipa Saha"'
Autor:
Oliver A. Kent, Manipa Saha, Etienne Coyaud, Helen E. Burston, Napoleon Law, Keith Dadson, Sujun Chen, Estelle M. Laurent, Jonathan St-Germain, Ren X. Sun, Yoshinori Matsumoto, Justin Cowen, Aaryn Montgomery-Song, Kevin R. Brown, Charles Ishak, Jose La Rose, Daniel D. De Carvalho, Housheng Hansen He, Brian Raught, Filio Billia, Peter Kannu, Robert Rottapel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mutations in RAS-MAPK pathway genes are implicated in Noonan-spectrum, yet up to 20% of cases have unknown cause. Here, the authors identify RREB1 underlying a 6p microdeletion RASopathy-like syndrome and show that RREB1, SIN3A and KDM1A form a trans
Externí odkaz:
https://doaj.org/article/7477dd54517347169cc4551af1667746
Autor:
Manipa Saha, Neha Deshpande, Abhinav Dubey, Debnath Pal, Hanudatta S. Atreya, Annapoorni Rangarajan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Attachment to the matrix is critical for the survival of adherent cells, whereas detachment triggers death by apoptosis. Therefore, solid tumors must acquire the ability to survive the stress of matrix-detachment to transit through circulation and se
Externí odkaz:
https://doaj.org/article/c7a40f3bbd5c4aaaa19291e59e875eb6
Autor:
Annapoorni Rangarajan, Sravanth K. Hindupur, Prashant Kumar, Sai A. Balaji, Shoiab Bukhari, Saurav Kumar, Manipa Saha
File contains supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b86cdc680d9bace860d3db8881a2b9
https://doi.org/10.1158/0008-5472.22417221.v1
https://doi.org/10.1158/0008-5472.22417221.v1
Autor:
Annapoorni Rangarajan, Sravanth K. Hindupur, Prashant Kumar, Sai A. Balaji, Shoiab Bukhari, Saurav Kumar, Manipa Saha
Cell detachment from the extracellular matrix triggers anoikis. Disseminated tumor cells must adapt to survive matrix deprivation, while still retaining the ability to attach at secondary sites and reinitiate cell division. In this study, we elucidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d594fe05da1fce763ca1b6b41732ae93
https://doi.org/10.1158/0008-5472.c.6509781.v1
https://doi.org/10.1158/0008-5472.c.6509781.v1
Autor:
Annapoorni Rangarajan, Sravanth K. Hindupur, Prashant Kumar, Sai A. Balaji, Shoiab Bukhari, Saurav Kumar, Manipa Saha
File contains figure legends for supplementary figure and method and material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5930fb6042bedf974329f30734aa52
https://doi.org/10.1158/0008-5472.22417218
https://doi.org/10.1158/0008-5472.22417218
Autor:
Helen E. Burston, Oliver A. Kent, Ren X. Sun, Justin Cowen, Daniel D. De Carvalho, Sujun Chen, Jonathan St-Germain, Robert Rottapel, Aaryn Montgomery-Song, Manipa Saha, Yoshinori Matsumoto, Napoleon Law, Housheng Hansen He, Kevin R. Brown, Peter Kannu, Jose La Rose, Keith Dadson, Charles A. Ishak, Filio Billia, Etienne Coyaud, Brian Raught, Estelle M.N. Laurent
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, Nature Communications, 11 (4673), ⟨10.1038/s41467-020-18483-9⟩
Nature Communications
Nature Communications, 2020, Nature Communications, 11 (4673), ⟨10.1038/s41467-020-18483-9⟩
RAS-MAPK signaling mediates processes critical to normal development including cell proliferation, survival, and differentiation. Germline mutation of RAS-MAPK genes lead to the Noonan-spectrum of syndromes. Here, we present a patient affected by a 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c26c38393f0bd745f6a39c677dc7ac5
https://doaj.org/article/7477dd54517347169cc4551af1667746
https://doaj.org/article/7477dd54517347169cc4551af1667746
Publikováno v:
Anoikis ISBN: 9783030738549
Normal epithelial and endothelial cells of the body undergo programmed cell death termed ‘anoikis’ when they are deprived of extra-cellular matrix (ECM) attachment [2, 3]. Cancer cells, on the other hand, can circumvent this process which enables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a279741f90b03c28b91649f91941099
https://doi.org/10.1007/978-3-030-73856-3_2
https://doi.org/10.1007/978-3-030-73856-3_2
Autor:
Sai A. Balaji, Saurav Kumar, Manipa Saha, Prashant Kumar, Annapoorni Rangarajan, Shoiab Bukhari, Sravanth K. Hindupur
Publikováno v:
Cancer Research. 78:1497-1510
Cell detachment from the extracellular matrix triggers anoikis. Disseminated tumor cells must adapt to survive matrix deprivation, while still retaining the ability to attach at secondary sites and reinitiate cell division. In this study, we elucidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72989d38fe755d075f1cef5e3dd7e158
https://doi.org/10.1158/0008-5472.can-17-2090
https://doi.org/10.1158/0008-5472.can-17-2090
Autor:
Stefan Knapp, Franziska Preuss, Jonathan St-Germain, Sebastian Mathea, Manipa Saha, Deep Chatterjee, Safal Shrestha, Brian Raught, Robert Rottapel, Natarajan Kannan
Publikováno v:
Structure. 28(11):1184-1196.e6
Unc-51-like kinase 4 (ULK4) is a pseudokinase that has been linked to the development of several diseases. Even though sequence motifs required for ATP binding in kinases are lacking, ULK4 still tightly binds ATP and the presence of the cofactor is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9426ec0e16a6a7841ea3ea99a4e8af50