Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Manila Amici"'
Autor:
Manila Amici, Laura Bonfili, Massimiliano Cuccioloni, Jeffrey N. Keller, Mauro Angeletti, Valentina Cecarini, Anna Maria Eleuteri
Publikováno v:
FEBS Journal. 275:5512-5526
The purpose of this review is to discuss the effect of natural antioxidant compounds as modulators of the 20S proteasome, a multi-enzymatic multi-catalytic complex present in the cytoplasm and nucleus of eukaryotic cells and involved in several cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82cb3b4fe5cd08cbbc0b9e4d920b3241
https://doi.org/10.1111/j.1742-4658.2008.06696.x
https://doi.org/10.1111/j.1742-4658.2008.06696.x
Autor:
Manila Amici, Mauro Angeletti, Jeffrey N. Keller, Anna Maria Eleuteri, Valentina Cecarini, Laura Bonfili
Publikováno v:
Brain Research. 1209:8-18
The role of amyloid-beta protein (Abeta) in the pathogenesis of Alzheimer's disease (AD) has been widely investigated and amyloid aggregates are considered a major cause of neuronal dysfunction. Increasing evidence has identified a correlation betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f394b122a2df72bd268c59c7172aeb
https://doi.org/10.1016/j.brainres.2008.03.003
https://doi.org/10.1016/j.brainres.2008.03.003
Autor:
Rosalia Tacconi, Gian Luigi Gianfranceschi, Manila Amici, Isabella Calzuola, Valentina Cecarini, Evandro Fioretti, Anna Maria Eleuteri, Mauro Angeletti, Laura Bonfili, Valeria Marsili, Michele Spina
Publikováno v:
Biochimie. 90:790-801
Wheat sprouts contain a very high level of organic phosphates and a powerful cocktail of different molecules such as enzymes, reducing glycosides and polyphenols. The antioxidant properties of wheat sprouts have been widely documented and it has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453ac5d4c5d81dd7a773454b0103f66a
https://doi.org/10.1016/j.biochi.2007.12.001
https://doi.org/10.1016/j.biochi.2007.12.001
Autor:
Mauro Angeletti, Anna Maria Eleuteri, Manila Amici, Valentina Cecarini, Jeffrey N. Keller, Jillian Gee, Evandro Fioretti
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1773(2):93-104
Reactive oxygen species (ROS) are generated as the result of a number of physiological and pathological processes. Once formed ROS can promote multiple forms of oxidative damage, including protein oxidation, and thereby influence the function of a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d5c2d4147b8e4ca78f38042fda0d4a
Autor:
Mauro Angeletti, Evandro Fioretti, Manila Amici, Massimiliano Cuccioloni, Anna Maria Eleuteri, Assuntina Pettinari
Publikováno v:
Antioxidants & Redox Signaling. 8:121-129
The effect of several polyphenols on the 20S proteasomes, both the constitutive and the LMP proteasomes, isolated from bovine tissues, has been investigated. Polyphenolic compounds show many biological activities such as antiviral, antibacterial, ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c660a29eec7ba0523a279d7d2e9bbc7f
https://doi.org/10.1089/ars.2006.8.121
https://doi.org/10.1089/ars.2006.8.121
Autor:
Stefania Pucciarelli, Mauro Angeletti, Evandro Fioretti, Manila Amici, Cristina Marchini, Anna Maria Eleuteri, Giulio Lupidi
Publikováno v:
International Journal of Biological Macromolecules. 28:321-330
The structure–function relationships occurring on the bovine thymus 20S proteasome, which exhibits the features of an immunoproteasome, have been studied. The investigation has been performed, essentially, using a fluorimetric approach, taking adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec31e7e052c607d980da474d95108162
https://doi.org/10.1016/s0141-8130(01)00132-5
https://doi.org/10.1016/s0141-8130(01)00132-5
Autor:
Mauro Angeletti, Giacomo Rossi, Jeffrey N. Keller, Anna Maria Eleuteri, Evandro Fioretti, Massimiliano Cuccioloni, Valentina Cecarini, Simone Barocci, Manila Amici
Publikováno v:
Journal of neuroscience research. 88(1)
Scrapie is a transmissible spongiform encephalopathy affecting the central nervous system in sheep. The key event in such neurodegeneration is the conversion of the normal prion protein (PrP C ) into the pathological isoform (PrP Sc ). Misfolded prio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6765e27ab6bd8574acf91a5b9102ee1a
https://pubmed.ncbi.nlm.nih.gov/19658198
https://pubmed.ncbi.nlm.nih.gov/19658198
Autor:
Evandro Fioretti, Laura Bonfili, Manila Amici, Rosalia Tacconi, Massimiliano Cuccioloni, Anna Maria Eleuteri, Mauro Angeletti, Jeffrey N. Keller, Valentina Cecarini
Publikováno v:
Biochimie. 91(9)
Natural occurring modulators of proteasome functionality are extensively investigated for their implication in cancer therapy. On the basis of our previous evidences both on proteasomal inhibition by monomeric polyphenols, and on the characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1073609e7fa8d90790f28ee3a86ad698
https://pubmed.ncbi.nlm.nih.gov/19527768
https://pubmed.ncbi.nlm.nih.gov/19527768
Autor:
Mauro Angeletti, Massimiliano Cuccioloni, L. Giuliani, Anna Maria Eleuteri, Laura Bonfili, Manila Amici, S. Grimaldi, Evandro Fioretti, Valentina Cecarini
Publikováno v:
Journal of Biomedicine and Biotechnology
(2009). doi:10.1155/2009/834239
info:cnr-pdr/source/autori:Eleuteri AM1; Amici M2; Bonfili L3; Cecarini V4; Cuccioloni M5; Grimaldi S6; Giuliani L7; Angeletti M8; Fioretti E9./titolo:50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems./doi:10.1155%2F2009%2F834239/rivista:Journal of Biomedicine and Biotechnology (Print)/anno:2009/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Biomedicine and Biotechnology, Vol 2009 (2009)
(2009). doi:10.1155/2009/834239
info:cnr-pdr/source/autori:Eleuteri AM1; Amici M2; Bonfili L3; Cecarini V4; Cuccioloni M5; Grimaldi S6; Giuliani L7; Angeletti M8; Fioretti E9./titolo:50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems./doi:10.1155%2F2009%2F834239/rivista:Journal of Biomedicine and Biotechnology (Print)/anno:2009/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Biomedicine and Biotechnology, Vol 2009 (2009)
Electromagnetic fields are an assessed cause of prolonging free radicals lifespan. This study was carried out to investigate the influence of extremely low frequency electromagnetic fields on protein oxidation and on the 20S proteasome functionality,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eac3ef261cdc94dfbe40ea2b79896f5
http://hdl.handle.net/11581/200324
http://hdl.handle.net/11581/200324
Autor:
Massimiliano Cuccioloni, Manila Amici, Anna Maria Eleuteri, Matteo Mozzicafreddo, Francesca Montecchia, Mauro Angeletti
Publikováno v:
Journal of molecular recognition : JMR. 22(1)
The proteasome has a crucial part in the degradation of normal, damaged, mutant or misfolded proteins within both the ubiquitin ATP-dependent and the ubiquitin ATP-independent pathways. Proteasome-mediated proteolysis is modulated by diverse factors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465991679a25c427f8654968caa1cf83
https://pubmed.ncbi.nlm.nih.gov/19006106
https://pubmed.ncbi.nlm.nih.gov/19006106