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Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-15
Autor:
Veerapandian, Malaisamy, Hemavathy, Nagarajan, Karthika, Alagesan, Manikandan, Jayaraman, Vetrivel, Umashankar, Jeyakanthan, Jeyaraman
Publikováno v:
Molecular Simulation; Feb2024, Vol. 50 Issue 3, p161-177, 17p
Publikováno v:
Journal of Vector Borne Diseases, Vol 53, Iss 2, Pp 179-184 (2016)
Background & objectives: It is well reported that exhaled CO 2 and skin odour from human being assist female mosquitoes to locate human host. Basically, the receptors for this activity are expressed in cpA neurons. In both Aedes aegypti and Anopheles
Externí odkaz:
https://doaj.org/article/d7a3a3a78a4148c78f38dac64e73d441
Autor:
Krishna Ramadas, Manikandan Jayaraman
Publikováno v:
Journal of molecular graphicsmodelling. 101
Growing concern about the difficulty in diagnosis and treatments of drug-resistant tuberculosis falls under the major global health issues. There is an urgent need for finding novel strategies to develop drugs or bioactive molecules against the globa
Publikováno v:
Journal of Molecular Liquids. 335:116204
The pandemic prevalence of tuberculosis (TB) caused by increasing drug-resistant Mycobacterium tuberculosis (Mtb) strains has posed severe global health threats. The resistance developed against conventional drugs within Mtb strains has complicated T
Publikováno v:
Journal of Molecular Graphics and Modelling. 100:107708
Cytochrome P450 oxidoreductase (POR) is a steroidogenic and drug-metabolizing enzyme. It helps in the NADPH dependent transfer of electrons to cytochrome P450 (CYP) enzymes for their biological activity. In this study, we employed integrative computa
Publikováno v:
Gene. 720
The enzyme β-Ketoacyl ACP synthase I (KasA) is a potent drug target in mycolic acid pathway of Mycobacterium tuberculosis (Mtb). In the present study, we investigated the structural dynamics of wild-type (WT) and mutants KasA (D66N, G269S, G312S, an
Autor:
Kannan Muthu, Manivel Panneerselvam, Krishna Ramadas, Manikandan Jayaraman, Nishith Saurav Topno
Publikováno v:
Cellular Signalling. 27:739-755
ARHI, a putative tumor suppressor protein with unique 32 amino acid extension in the N-terminal region, differs from oncogenes Ras and Rap, negatively regulates STAT3 signaling and inhibits the migration of ovarian cancer cells. ARHI associates direc