Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Manijeh Phillips"'
Autor:
Michael C. Lawrence, Manijeh Phillips, Nalinda P. Wickramasinghe, Faramarz Ismail-Beigi, Nelson B. Phillips, Jonathan Whittaker, Kelley Carr, Michael D. Glidden, Yanwu Yang, Khadijah Aldabbagh, Nischay Rege, Yen Shan Chen, Michael A. Weiss, Mamuni Swain, Yi Peng, Vivien C. Yee
Thermal degradation of insulin complicates its delivery and use. Previous efforts to engineer ultra-stable analogs were confounded by prolonged cellular signaling in vivo, of unclear safety and complicating mealtime therapy. We therefore sought an ul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f08dc8ce4ba088ce3c8e664fec15372
https://europepmc.org/articles/PMC5766902/
https://europepmc.org/articles/PMC5766902/
Autor:
Manijeh Phillips, Scott A. Strong, Silvio Danese, Jon D. Vogel, Carol A. de la Motte, Gail A. West, Claudio Fiocchi, Joseph Willis
Publikováno v:
Gastroenterology. 126:63-80
Background & Aims: The CD40 pathway is a key mediator of inflammation and autoimmunity. We investigated cell adhesion molecule (CAM) up-regulation and chemokine production by CD40-positive human intestinal fibroblasts (HIF) and microvascular endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6011021b5138d7f04ddd701f9004df3b
https://doi.org/10.1053/j.gastro.2003.10.046
https://doi.org/10.1053/j.gastro.2003.10.046
Publikováno v:
Clinical and Experimental Immunology. 123:210-218
SUMMARYCachexia is one of the prominent features of advanced tuberculosis (TB) seen in association with increased expression of the monokine TNF-α. Several mycobacterial proteins, including PPD, stimulate TNF-α secretion from monocytes. Host factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eabf50f903d6c665f7355d1379a6066
https://doi.org/10.1046/j.1365-2249.2001.01439.x
https://doi.org/10.1046/j.1365-2249.2001.01439.x
Autor:
Nelson B. Phillips, Manijeh Phillips, Htin Aung, Jeffrey J. Wisnieski, Lloyd A. Culp, Robert S. Wallis, Thomas M. Daniel, Zahra Toossi, Lynn E. Averill, Jerrold J. Ellner
Publikováno v:
Journal of Clinical Investigation. 98:1261-1268
Native 30-kD antigen, also known as alpha antigen, is a fibronectin-binding protein that is secreted by live Mycobacterium tuberculosis. This antigen may play an important biological role in the host-parasite interaction since it elicits delayed type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b416b243222da07b986c3e779c886361
https://doi.org/10.1172/jci118910
https://doi.org/10.1172/jci118910
Autor:
Jeffry Katz, Miquel Sans, Claudio Fiocchi, Silvio Danese, Carol A. de la Motte, Brenda Rivera-Reyes, Manijeh Phillips, Gail West, Heitor Siffert Pereira de Souza
Background & Aims: Fractalkine (FKN/CX3CL1) is a unique chemokine combining adhesive and chemotactic properties. We investigated FKN production by the mucosal microvasculature in inflammatory bowel disease (IBD), its capacity for leukocyte recruitmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5d77cee81b0c200771944408ccc692
https://europepmc.org/articles/PMC2194659/
https://europepmc.org/articles/PMC2194659/
Autor:
Richard C.K. Wong, Manijeh Phillips, Robert O'Shea, Gail A. West, Gregory S. Cooper, Thomas S. McCormick, Jeffry Katz, Karen M. Harnett, Michael V. Sivak, Amitabh Chak, Gerard Isenberg, Piero Biancani, Joseph Willis, Ling Cheng, Claudio Fiocchi, Florian Rieder, Andrew Catanzaro, Anthony B. Post, Monica Ray
Publikováno v:
Gastroenterology. 132(1)
Background & Aims: Gastroesophageal reflux disease is a condition frequently associated with esophagitis and motor abnormalities. Recent evidence suggests that proinflammatory cytokines, such as interleukin (IL)-1β and IL-6, may be implicated becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fc8afa3b625486ee9c72204da7ba75
https://pubmed.ncbi.nlm.nih.gov/17241868
https://pubmed.ncbi.nlm.nih.gov/17241868
Autor:
Claudio Fiocchi, Carol A. de la Motte, Silvio Danese, Roberto Pola, Antonio Gasbarrini, Sergio Rutella, Joe Willis, Miquel Sans, Gail A. West, Manijeh Phillips, Cristina Graziani
Background & Aims: Angiogenesis is a critical component of neoplastic and chronic inflammatory disorders, but whether angiogenesis also occurs in inflammatory bowel disease (IBD) has yet to be established. We assessed mucosal vascularization, express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2606a8f9d324ae2d6ade98968e065a34
Autor:
Amy G. Hise, Rhonda Larkin, Robert S. Wallis, Beate Kampmann, Jerrold J. Ellner, Ho Yeon Song, Daniel F. Hoft, Katherine Landen, Qing Li, Manijeh Phillips, Richard F. Silver, Seon Hee Cheon
Publikováno v:
Clinical and diagnostic laboratory immunology. 9(4)
The development of new tuberculosis (TB) vaccines will require the identification of correlates of human protection. This study examined the balance between immunity and virulence in a whole blood infection model in which intracellular mycobacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8234781b01cab070fce784a4c7b1233a
https://pubmed.ncbi.nlm.nih.gov/12093693
https://pubmed.ncbi.nlm.nih.gov/12093693
Autor:
Jerrold J. Ellner, Ho Yeon Song, Solange Alves Vinhas, Reynaldo Dietze, Moises Palaci, Seon Hee Cheon, Amy G. Hise, Robert S. Wallis, Fabiola Karla Correa Ribeiro, Katherine Landen, Manijeh Phillips
Publikováno v:
The Journal of infectious diseases. 183(8)
The bactericidal activity of orally administered antituberculosis (anti-TB) drugs was determined in a whole blood culture model of intracellular infection in which microbial killing reflects the combined effects of drug and immune mechanisms. Rifampi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ced50e76a408e8319278b9c9a71c11
https://pubmed.ncbi.nlm.nih.gov/11262217
https://pubmed.ncbi.nlm.nih.gov/11262217
Autor:
John L. Johnson, Luciléia Teixeira, Jerrold J. Ellner, Kathleen D. Eisenach, Reynaldo Dietze, Robert S. Wallis, Barbara Demchuk, Mark Perkins, Alice Namale, Roy D. Mugerwa, Manijeh Phillips, Christopher C. Whalen, Moses Joloba
Patients vary considerably in their response to treatment of pulmonary tuberculosis. Although several studies have indicated that adverse outcomes are more likely in those patients with delayed sputum sterilization, few tools are available to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965e7eeb98efa3a0154188b1714c645e
https://europepmc.org/articles/PMC4752200/
https://europepmc.org/articles/PMC4752200/