Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Manija A. Kazmi"'
Autor:
Manija A. Kazmi, David S. Thaler, Karina C. Åberg, Jordan M. Mattheisen, Thomas Huber, Thomas P. Sakmar
Publikováno v:
Frontiers in Epidemiology, Vol 3 (2023)
ObjectivesTo develop a biological diary (CoronaCal) that allows anyone in the community to collect and store serial saliva samples and chart symptoms on ordinary printer paper.MethodsDiaries were analyzed for the presence of SARS-CoV-2 RNA using esta
Externí odkaz:
https://doaj.org/article/b6567220abfd4129b1e6d4e5a530272f
Autor:
Angelina S. Bortoletto, W. Vallen Graham, Gabriella Trout, Alessandra Bonito‐Oliva, Manija A. Kazmi, Jing Gong, Emily Weyburne, Brandy L. Houser, Thomas P. Sakmar, Ronald J. Parchem
Publikováno v:
Advanced Science, Vol 9, Iss 34, Pp n/a-n/a (2022)
Abstract Type 2 diabetes mellitus (T2D) is a major public health concern and is characterized by sustained hyperglycemia due to insulin resistance and destruction of insulin‐producing β cells. One pathological hallmark of T2D is the toxic accumula
Externí odkaz:
https://doaj.org/article/fc13ca5e48c84fccafa8805eefa0fd48
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104060- (2022)
Summary: The photoreceptor rhodopsin (Rho) becomes active when a tethered inverse agonist ligand (11CR) is photoconverted to an agonist (ATR). The ligand-binding pocket of inactive rhodopsin is completely enclosed, whereas active rhodopsin displays p
Externí odkaz:
https://doaj.org/article/8e6b19293d7d421e80203b3b2b460adc
Autor:
Shahar Barbash, Torbjörn Persson, Emily Lorenzen, Manija A. Kazmi, Thomas Huber, Thomas P. Sakmar
Publikováno v:
iScience, Vol 11, Iss , Pp 366-374 (2019)
Summary: A recent phylogenetic analysis showed global co-evolution of G protein-coupled receptors (GPCRs) and receptor-activity-modifying proteins (RAMPs) suggesting global interactions between these two protein families. Experimental validation of t
Externí odkaz:
https://doaj.org/article/d4a1054777b746d08de3e6f2299b7cd2
Publikováno v:
BioTechniques, Vol 21, Iss 2, Pp 304-311 (1996)
A method for high-level expression of a functionally active, recombinant human red cone opsin was developed by adding the coding sequence for the C-terminal epitope of bovine rhodopsin onto the C terminus of the cone opsin and cloning the resulting c
Externí odkaz:
https://doaj.org/article/47cc874fb90c4b24a8736ee3fc0f83a1
Autor:
David S. Thaler, Manija A. Kazmi, Karina C. Åberg, Jordan M. Mattheisen, Thomas Huber, Thomas P. Sakmar
Publikováno v:
Frontiers in Epidemiology. 3
BackgroundThe testing of saliva samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA has become a useful and common method to diagnose coronavirus disease 2019 (Covid-19). However, there are limited examples of serial testing
Autor:
Lea S. van Husen, Simon J. Elsässer, Thomas P. Sakmar, Minh Nguyen Trung, Sophia Schedin-Weiss, Manija A. Kazmi, Lars O. Tjernberg, Bengt Winblad
Publikováno v:
Journal of Alzheimer's Disease
The amyloid-β protein precursor (AβPP) is critical in the pathophysiology of Alzheimer's disease (AD), since two-step proteolytic processing of AβPP generates the neurotoxic amyloid-β peptide (Aβ). We developed a dual fluorescence labeling syste
While the number of high-resolution structures of ligand-bound G protein-coupled receptors (GPCRs) has been steadily climbing, ligand binding and unbinding pathways remain largely undefined. The visual photoreceptor rhodopsin (Rho) represents a curio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb5900589898460f9316328e920eaff2
https://doi.org/10.1101/2021.05.24.445474
https://doi.org/10.1101/2021.05.24.445474
Autor:
Thomas P. Sakmar, Thomas Huber, Shahar Barbash, Torbjörn Persson, Manija A. Kazmi, Emily Lorenzen
Publikováno v:
iScience
iScience, Vol 11, Iss, Pp 366-374 (2019)
iScience, Vol 11, Iss, Pp 366-374 (2019)
Summary A recent phylogenetic analysis showed global co-evolution of G protein-coupled receptors (GPCRs) and receptor-activity-modifying proteins (RAMPs) suggesting global interactions between these two protein families. Experimental validation of th
Autor:
Margaret S. Ebert, Asaf Gal, Leonora Olivos-Cisneros, Yuko Ulrich, Manija A. Kazmi, Taylor Hart, Ingrid Fetter-Pruneda, Peter R. Oxley, Cornelia I. Bargmann, Jennifer L. Garrison, Daniel J. C. Kronauer
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 6, p e3001305 (2021)
PLoS Biology, Vol 19, Iss 6, p e3001305 (2021)
Oxytocin/vasopressin-related neuropeptides are highly conserved and play major roles in regulating social behavior across vertebrates. However, whether their insect orthologue, inotocin, regulates the behavior of social groups remains unknown. Here,