Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Manija A Kazmi"'
Autor:
Ingrid Fetter-Pruneda, Taylor Hart, Yuko Ulrich, Asaf Gal, Peter R Oxley, Leonora Olivos-Cisneros, Margaret S Ebert, Manija A Kazmi, Jennifer L Garrison, Cornelia I Bargmann, Daniel J C Kronauer
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001305 (2021)
Oxytocin/vasopressin-related neuropeptides are highly conserved and play major roles in regulating social behavior across vertebrates. However, whether their insect orthologue, inotocin, regulates the behavior of social groups remains unknown. Here,
Externí odkaz:
https://doaj.org/article/a67e1de7c735435e9c074c81cd34cadd
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104060- (2022)
Summary: The photoreceptor rhodopsin (Rho) becomes active when a tethered inverse agonist ligand (11CR) is photoconverted to an agonist (ATR). The ligand-binding pocket of inactive rhodopsin is completely enclosed, whereas active rhodopsin displays p
Externí odkaz:
https://doaj.org/article/8e6b19293d7d421e80203b3b2b460adc
Autor:
Shahar Barbash, Torbjörn Persson, Emily Lorenzen, Manija A. Kazmi, Thomas Huber, Thomas P. Sakmar
Publikováno v:
iScience, Vol 11, Iss , Pp 366-374 (2019)
Summary: A recent phylogenetic analysis showed global co-evolution of G protein-coupled receptors (GPCRs) and receptor-activity-modifying proteins (RAMPs) suggesting global interactions between these two protein families. Experimental validation of t
Externí odkaz:
https://doaj.org/article/d4a1054777b746d08de3e6f2299b7cd2
Autor:
David S. Thaler, Manija A. Kazmi, Karina C. Åberg, Jordan M. Mattheisen, Thomas Huber, Thomas P. Sakmar
Publikováno v:
Frontiers in Epidemiology. 3
BackgroundThe testing of saliva samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA has become a useful and common method to diagnose coronavirus disease 2019 (Covid-19). However, there are limited examples of serial testing
Autor:
Angelina S. Bortoletto, W. Vallen Graham, Gabriella Trout, Alessandra Bonito‐Oliva, Manija A. Kazmi, Jing Gong, Emily Weyburne, Brandy L. Houser, Thomas P. Sakmar, Ronald J. Parchem
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(34)
Type 2 diabetes mellitus (T2D) is a major public health concern and is characterized by sustained hyperglycemia due to insulin resistance and destruction of insulin-producing β cells. One pathological hallmark of T2D is the toxic accumulation of hum
Autor:
Lea S. van Husen, Simon J. Elsässer, Thomas P. Sakmar, Minh Nguyen Trung, Sophia Schedin-Weiss, Manija A. Kazmi, Lars O. Tjernberg, Bengt Winblad
Publikováno v:
Journal of Alzheimer's Disease
The amyloid-β protein precursor (AβPP) is critical in the pathophysiology of Alzheimer's disease (AD), since two-step proteolytic processing of AβPP generates the neurotoxic amyloid-β peptide (Aβ). We developed a dual fluorescence labeling syste
While the number of high-resolution structures of ligand-bound G protein-coupled receptors (GPCRs) has been steadily climbing, ligand binding and unbinding pathways remain largely undefined. The visual photoreceptor rhodopsin (Rho) represents a curio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb5900589898460f9316328e920eaff2
https://doi.org/10.1101/2021.05.24.445474
https://doi.org/10.1101/2021.05.24.445474
Autor:
Thomas P. Sakmar, Thomas Huber, Shahar Barbash, Torbjörn Persson, Manija A. Kazmi, Emily Lorenzen
Publikováno v:
iScience
iScience, Vol 11, Iss, Pp 366-374 (2019)
iScience, Vol 11, Iss, Pp 366-374 (2019)
Summary A recent phylogenetic analysis showed global co-evolution of G protein-coupled receptors (GPCRs) and receptor-activity-modifying proteins (RAMPs) suggesting global interactions between these two protein families. Experimental validation of th
Publikováno v:
BioTechniques, Vol 21, Iss 2, Pp 304-311 (1996)
A method for high-level expression of a functionally active, recombinant human red cone opsin was developed by adding the coding sequence for the C-terminal epitope of bovine rhodopsin onto the C terminus of the cone opsin and cloning the resulting c
Externí odkaz:
https://doaj.org/article/47cc874fb90c4b24a8736ee3fc0f83a1
Autor:
Margaret S. Ebert, Asaf Gal, Leonora Olivos-Cisneros, Yuko Ulrich, Manija A. Kazmi, Taylor Hart, Ingrid Fetter-Pruneda, Peter R. Oxley, Cornelia I. Bargmann, Jennifer L. Garrison, Daniel J. C. Kronauer
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 6, p e3001305 (2021)
PLoS Biology, Vol 19, Iss 6, p e3001305 (2021)
Oxytocin/vasopressin-related neuropeptides are highly conserved and play major roles in regulating social behavior across vertebrates. However, whether their insect orthologue, inotocin, regulates the behavior of social groups remains unknown. Here,