Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Manickavasagam Sundaram"'
Autor:
Sylvia Y.M. Yao, Mark F. Vickers, Manickavasagam Sundaram, Amy M. L. Ng, James D. Young, Carol E. Cass, Stephen A. Baldwin
Publikováno v:
Journal of Biological Chemistry. 277:24938-24948
The human (h) and rat (r) equilibrative (Na(+)-independent) nucleoside transporters (ENTs) hENT1, rENT1, hENT2, and rENT2 belong to a family of integral membrane proteins with 11 transmembrane domains (TMs) and are distinguished functionally by diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6547ae8e0c3088d30cc06fec5efd372
https://doi.org/10.1074/jbc.m200966200
https://doi.org/10.1074/jbc.m200966200
Autor:
Stephen A. Baldwin, Manickavasagam Sundaram, Jean C. Ingram, Carol E. Cass, Zoe A. Berry, Fatima Abidi, James D. Young, Sylvia Y.M. Yao
Publikováno v:
Journal of Biological Chemistry. 276:45270-45275
The human equilibrative nucleoside transporter hENT1, the first identified member of the ENT family of integral membrane proteins, is the primary mechanism for the cellular uptake of physiologic nucleosides, including adenosine, and many anti-cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea921d64b1100c1b15a33f147eb44c79
https://doi.org/10.1074/jbc.m107169200
https://doi.org/10.1074/jbc.m107169200
Autor:
Stephen A. Baldwin, Carol E. Cass, Sylvia Y.M. Yao, Manickavasagam Sundaram, Amy M. L. Ng, James D. Young
Publikováno v:
Biochemistry. 40:8146-8151
The rat equilibrative nucleoside transporters rENT1 and rENT2 belong to a family of integral membrane proteins with 11 potential transmembrane segments (TMs) and are distinguished functionally by differences in sensitivity to inhibition by nitrobenzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660fd574e43c4cd9ccfab11f1148946f
https://doi.org/10.1021/bi0101805
https://doi.org/10.1021/bi0101805
Autor:
Sylvia Y. M. YAO, Manickavasagam SUNDARAM, Eugene G. CHOMEY, Carol E. CASS, Stephen A. BALDWIN, James D. YOUNG
Publikováno v:
Biochemical Journal. 353:387-393
The human and rat equilibrative nucleoside transporter proteins hENT1, rENT1, hENT2 and rENT2 belong to a family of integral membrane proteins with 11 potential transmembrane segments (TMs), and are distinguished functionally by differences in transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59312324b65e78c5f36a49b67c34045
https://doi.org/10.1042/bj3530387
https://doi.org/10.1042/bj3530387
Autor:
James D. Young, Rajam S. Mani, Manickavasagam Sundaram, Carol E. Cass, Stephen A. Baldwin, Mark F. Vickers, Douglas L. Hogue
Publikováno v:
Biochemical Journal. 339:21-32
We have produced recombinant human equilibrative nucleoside transporter (hENT1) in the yeast Saccharomyces cerevisiae and have compared the binding of inhibitors of equilibrative nucleoside transport with the wild-type transporter and a N-glycosylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fae01a0bd7f0e5d822bd59df294c49ae
https://doi.org/10.1042/bj3390021
https://doi.org/10.1042/bj3390021
Autor:
Nick Beaumont, Christine E. Boumah, Manickavasagam Sundaram, Carol E. Cass, Sylvia Y.M. Yao, Imogen Coe, Francis Y. P. Kwong, Anthony Davies, Mark Griffiths, Stephen A. Baldwin, James D. Young
Publikováno v:
Nature Medicine. 3:89-93
In most mammalian cells nucleoside uptake occurs primarily via broad-specificity, es (e, equilibrative; 5, sensitive to NBMPR inhibition) transporters that are potently inhibited by nitrobenzylthioinosine (NBMPR). These transporters are essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7e2cbbc2f6fcd0755ffbfa1140e257
https://doi.org/10.1038/nm0197-89
https://doi.org/10.1038/nm0197-89
Autor:
Manickavasagam Sundaram, Carol E. Cass, James D. Young, Sylvia Y.M. Yao, Amy M. L. Ng, Stephen A. Baldwin
Publikováno v:
Molecular membrane biology. 18(2)
In the present study, one has determined the relative role of plasma membrane equilibrative (Na+-independent) ENT nucleoside transport proteins (particularly ENT2) in the uptake of antiviral nucleoside analogues for comparison with the previously rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b38cbc07f5bdb083c9acbd5dd700982
https://pubmed.ncbi.nlm.nih.gov/11463208
https://pubmed.ncbi.nlm.nih.gov/11463208
Autor:
James D. Young, Mark Griffiths, Amy M. L. Ng, Sylvia Y.M. Yao, Stephen A. Baldwin, Carol E. Cass, Manickavasagam Sundaram
Publikováno v:
The Journal of biological chemistry. 273(34)
We have recently isolated cDNAs from human placenta and rat jejunum encoding the prototypic human and rat equilibrative nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporters hENT1 and rENT1. The two proteins (456 and 457 residues, Mr 50,00
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ff9d9f4cc0ba3102654e584c803b46
https://pubmed.ncbi.nlm.nih.gov/9705281
https://pubmed.ncbi.nlm.nih.gov/9705281
Publikováno v:
The Journal of biological chemistry. 273(6)
The hypothesis that the cellular uptake of retinol involves the specific interaction of a plasma membrane receptor with serum retinol-binding protein (RBP) at the extracellular surface followed by ligand transfer to cytoplasmic cellular retinol-bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2ac7a11e490fe4efd6d1bee30e78bb
https://pubmed.ncbi.nlm.nih.gov/9452451
https://pubmed.ncbi.nlm.nih.gov/9452451
Publikováno v:
Retinoid Protocols ISBN: 9780896034389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0c90d8e3cc9947678c051e1e15ed690
https://doi.org/10.1385/0-89603-438-0:141
https://doi.org/10.1385/0-89603-438-0:141
