Výsledky vyhledávání - "Manicassamy Balaji"

Akademický článek

Expression of Ebolavirus glycoprotein on the target cells enhances viral entry

Publikováno v: Virology Journal, Vol 6, Iss 1, p 75 (2009)

Abstract Background Entry of Ebolavirus to the target cells is mediated by the viral glycoprotein GP. The native GP exists as a homotrimer on the virions and contains two subunits, a surface subunit (GP1) that is involved in receptor binding and a tr

Externí odkaz: https://doaj.org/article/14d742b8079b4c5c9f536ab53fd2aa04

Zobrazit plný text záznamu

Akademický článek

Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding

Autor: Uprichard Susan L, Manicassamy Balaji, Rothwangl Katharina B, Rong Lijun

Publikováno v: Virology Journal, Vol 5, Iss 1, p 46 (2008)

Abstract Background Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors including CD81. In this study, alanine substit

Externí odkaz: https://doaj.org/article/a7c3e4174d1d4514b22ee2ff2ef60a54

Zobrazit plný text záznamu

Report

Algorithmic Bio-surveillance For Precise Spatio-temporal Prediction of Zoonotic Emergence

Autor: Dhanoa, Jaideep, Manicassamy, Balaji, Chattopadhyay, Ishanu

Viral zoonoses have emerged as the key drivers of recent pandemics. Human infection by zoonotic viruses are either spillover events -- isolated infections that fail to cause a widespread contagion -- or species jumps, where successful adaptation to t

Externí odkaz: http://arxiv.org/abs/1801.07807

Zobrazit plný text záznamu

Report

Mathematical analysis of a mouse experiment suggests little role for resource depletion in controlling influenza infection within host

Autor: Ahmed, Hasan, Moore, James, Manicassamy, Balaji, Garcia-Sastre, Adolfo, Handel, Andreas, Antia, Rustom

How important is resource depletion (e.g. depletion of target cells) in controlling infection within a host? And how can we distinguish between resource depletion and other mechanisms that may contribute to decline of pathogen load or lead to pathoge

Externí odkaz: http://arxiv.org/abs/1705.02565

Zobrazit plný text záznamu