Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Manica Cerne"'
Publikováno v:
Drug and Chemical Toxicology. 36:263-269
The toxicity of amiodarone Lek formulation (test formulation) was investigated after a single intravenous (i.v.) administration to mice and rats. When compared to the reference item, Cordarone (Cordarone(®); Wyeth Pharmaceuticals Inc., Collegeville,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a72913836adf14c9d2cef0373ca7523
https://doi.org/10.3109/01480545.2012.710628
https://doi.org/10.3109/01480545.2012.710628
Publikováno v:
Journal of Microencapsulation. 27:572-582
LK-423 is a phthalimido-desmuramyl-dipeptide derivative with immunomodulating activity. In the present study the therapeutic efficacy of a colon-specific drug delivery system#x2013;LK-423 microcapsules#x2013;was examined in the 2,4,6-trinitrobenzene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0176bd493a27e3bd4c5f983e97d3e3
https://doi.org/10.3109/02652048.2010.501393
https://doi.org/10.3109/02652048.2010.501393
Publikováno v:
Acta veterinaria. 60:173-182
The aim of our study was to determine the prevalence and the intensity of infection with Helicobacter sp. in a group of 23 apparently healthy dogs in order to describe the morphological features of Helicobacters, to detect histopathological changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b3e77d89c1209d785443285809f279
https://doi.org/10.2298/avb1003173g
https://doi.org/10.2298/avb1003173g
Publikováno v:
Veterinarski Glasnik, Vol 62, Iss 3-4, Pp 143-152 (2008)
The aims of our study were to determinate the prevalence of helicobacter in a population of Slovenian dogs, to characterize the intensity of infection and to find out if the epidemiological parameters i. e. age, feeding regimen, gender, breed, locati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cf30ebbf92908af29e98efe3eb371d
https://doi.org/10.2298/vetgl0804143g
https://doi.org/10.2298/vetgl0804143g
Autor:
Aleš Obreza, Marko Oblak, Gorazd Drevenšek, Manica Cerne, Anamarija Zega, Luka Peternel, Mateja Stempelj, Metka V. Budihna, Lovro Stanovnik, Uroš Urleb
Publikováno v:
Thrombosis and Haemostasis. 95:294-300
SummaryThe main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group. A possibility that a strong basic group of LK-732 might contribute to the mast cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16693f67331ee15cf5d8d424110cfd9
https://doi.org/10.1160/th05-10-0683
https://doi.org/10.1160/th05-10-0683
Autor:
Metka V. Budihna, Uro Urleb, Luka Peternel, Anamarija Zega, Anton talc, Mojca Stegnar, Gorazd Drevenek, Manica Cerne, Mojca Boic
Publikováno v:
ResearcherID
SummaryThe antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold (LK-732, LK-639 and LK-731) and their amidoxime prodrugs (LK-658, LK-633 and LK-730) was studied in comparison to argatroban and nadroparin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29be89c75af96aa5f31b2a2eeae90738
https://doi.org/10.1160/th04-10-0676
https://doi.org/10.1160/th04-10-0676
Publikováno v:
Phytochemicals-Bioactivities and Impact on Health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494c850e1a780c7f7dced9f864a27391
http://www.intechopen.com/articles/show/title/first-pass-metabolism-changes-after-long-term-garlic-supplementation
http://www.intechopen.com/articles/show/title/first-pass-metabolism-changes-after-long-term-garlic-supplementation
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 15(10)
Multiple blood sampling in rat pharmacokinetic (PK) and toxicokinetic studies can result in a pathophysiological response and misleading data interpretation. This study investigated whether these drawbacks can be minimized by replacing withdrawn bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e05328270bb06b0f717bce852b8aaa26
https://pubmed.ncbi.nlm.nih.gov/19789506
https://pubmed.ncbi.nlm.nih.gov/19789506
Publikováno v:
Journal of pharmacological and toxicological methods. 61(1)
Introduction Permanent implantation of vascular catheters allows multiple blood sampling from the experimental animal. The aim of the study was firstly to establish four cannulation procedures in rats, which will result in high rate of catheter paten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d377260d7bc048dfb124cad254e4d1b3
https://pubmed.ncbi.nlm.nih.gov/19622393
https://pubmed.ncbi.nlm.nih.gov/19622393
Autor:
Mateja Stempelj, Gorazd Drevenšek, Uroš Urleb, Metka V. Budihna, Manica Cerne, Lovro Stanovnik, Luka Peternel
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 55
Many basic compounds, including numerous drugs, can release histamine and other infl ammatory mediators from mast cells [1]. Drug-induced degranulation of mast cells is an undesired effect and therefore should be avoided. One of the consequences of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb9c3788e9d49e7151372828bff9f6d
https://pubmed.ncbi.nlm.nih.gov/16705372
https://pubmed.ncbi.nlm.nih.gov/16705372