Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mani Ordoubadi"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 398 (2024)
Designing spray-dried particles for inhalation aims at specific physicochemical properties including a respirable aerodynamic diameter and adequate powder dispersibility. Leucine, an amphiphilic amino acid, has been shown to aid in optimizing bulk po
Externí odkaz:
https://doaj.org/article/12b805a38cd34eb5a643f951f85a2019
Publikováno v:
KONA Powder and Particle Journal, Vol 40, Iss 0, Pp 149-171 (2022)
Spray drying is gaining traction in the pharmaceutical industry as one of the processing methods of choice for the manufacture of solid dosage forms intended for pulmonary, oral, and parenteral delivery. This process is particularly advantageous beca
Externí odkaz:
https://doaj.org/article/cb35d5619cc7469c80967dd9a6c6d31e
Autor:
Mani Ordoubadi, Kimberly B. Shepard, Hui Wang, Zheng Wang, Amanda M. Pluntze, Joseph P. Churchman, Reinhard Vehring
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 435 (2023)
Carrier-free spray-dried dispersions for pulmonary delivery, for which the demand is growing, frequently require the incorporation of dispersibility-enhancing excipients into the formulations to improve the efficacy of the dosage form. One of the mos
Externí odkaz:
https://doaj.org/article/20d0c84ee1354331a593f8f23866d5fb
Autor:
Mani Ordoubadi, Asghar Farhadi, Firoozeh Yeganehdoust, Homayoon Emdad, Mahmood Yaghoubi, Ebrahim Goshtasebi Rad
Publikováno v:
Journal of Applied Fluid Mechanics, Vol 9, Iss 3, Pp 1477-1490 (2016)
In this article the possibility to use Eulerian approach in the conventional ISPH method in simulation of internal fluid flows is studied. The use of Eulerian approach makes it possible to use non-uniform particle distributions to increase the resolu
Externí odkaz:
https://doaj.org/article/9f19b1880031481d9e5cc9ed1b5fd5c2
Publikováno v:
KONA Powder and Particle Journal. 40:149-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2647fdd06da1cf803e5be457ec4dd66c
https://doi.org/10.14356/kona.2023012
https://doi.org/10.14356/kona.2023012
Publikováno v:
Aerosol Science and Technology. 55:901-919
The purpose of this study was twofold: to investigate leucine crystallization kinetics in co-solvent spray drying for a deeper understanding of the morphology and formation process of spray-dried c...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038bcab3c310f5ae73c6f2f15b8f5302
https://doi.org/10.1080/02786826.2021.1904129
https://doi.org/10.1080/02786826.2021.1904129
Autor:
Hui Wang, Mani Ordoubadi, Patrick Connaughton, Kellisa Lachacz, Nicholas Carrigy, Scott Tavernini, Andrew R. Martin, Warren H. Finlay, David Lechuga-Ballesteros, Reinhard Vehring
Publikováno v:
Pharmaceutical research. 39(4)
To develop a new lipid-based particle formulation platform for respiratory drug delivery applications. To find processing conditions for high surface rugosity and manufacturability. To assess the applicability of the new formulation method to differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2016349b587a22203c46da41387a6a
https://pubmed.ncbi.nlm.nih.gov/35364777
https://pubmed.ncbi.nlm.nih.gov/35364777
Autor:
Mark Nicholas, David Lechuga-Ballesteros, Jonathan P. Reid, Hui Wang, Mani Ordoubadi, Sandra Gracin, Reinhard Vehring, Nicholas B. Carrigy, Warren H. Finlay, Florence K. A. Gregson
Publikováno v:
Ordoubadi, M, Gregson, F K A, Wang, H, Carrigy, N B, Reid, J P & Vehring, R 2021, ' Trileucine as a dispersibility enhancer of spray-dried inhalable microparticles ', Journal of Controlled Release, vol. 336, pp. 522-536 . https://doi.org/10.1016/j.jconrel.2021.06.045
The formation of trileucine-containing spray-dried microparticles intended for pulmonary delivery was studied in depth. A single-particle method was employed to study the shell formation characteristics of trileucine in the presence of trehalose as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381e8b83dd453b90103546899805efc2
https://research-information.bris.ac.uk/ws/files/306086766/8_TrileucineSecond.pdf
https://research-information.bris.ac.uk/ws/files/306086766/8_TrileucineSecond.pdf
Publikováno v:
International journal of pharmaceutics. 610
Enteric infections have long constituted a silent epidemic responsible for hundreds of thousands of deaths around the world every year. Because of the global rise in antibiotic-resistant bacteria and the slow development of new small-molecule antibio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b28de8b2dc59bff11d5b9f10d728426
https://pubmed.ncbi.nlm.nih.gov/34742827
https://pubmed.ncbi.nlm.nih.gov/34742827
Autor:
Mani Ordoubadi, David Barona, Jonathan P. Reid, Allen E. Haddrell, David Lewis, Tanya Church, Rachael E. H. Miles, Reinhard Vehring, Florence K. A. Gregson
Publikováno v:
Gregson, F, Ordoubadi, M, Miles, R, Haddrell, A, Barona, D, Lewis, D, Church, T, Vehring, R & Reid, J 2019, ' Studies of Competing Evaporation Rates of Multiple Volatile Components from a Single Binary-Component Aerosol Droplet ', Physical Chemistry Chemical Physics, vol. 21, no. 19, pp. 9709-9719 . https://doi.org/10.1039/C9CP01158G
The simultaneous evaporation and condensation of multiple volatile components from multicomponent aerosol droplets leads to changes in droplet size, composition and temperature. Measurements and models that capture and predict these dynamic aerosol p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744d03fa4e9986e0080e470e3ca6d4b5
https://doi.org/10.1039/c9cp01158g
https://doi.org/10.1039/c9cp01158g