Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mani Mohindru"'
Publikováno v:
Journal of Virology. 85:3033-3040
Infection of the central nervous system (CNS) with Theiler’s murine encephalomyelitis virus (TMEV) induces an immune-mediated demyelinating disease in susceptible mouse strains such as SJL/J (H-2 s ) but not in strains such as C57BL/6 (H-2 b ). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2348c0709a458b024b8cdd94d3937cd4
https://doi.org/10.1128/jvi.02400-10
https://doi.org/10.1128/jvi.02400-10
Autor:
Daniel Gallo, Mani Mohindru, Alyson C. Fuller, Byung S. Kim, Min Hyung Kang, Young Hee Jin, Bongsu Kang
Publikováno v:
Journal of Virology. 81:11690-11702
Infection with Theiler's murine encephalomyelitis virus (TMEV) in the central nervous system (CNS) causes an immune system-mediated demyelinating disease similar to human multiple sclerosis in susceptible but not resistant strains of mice. To underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0bc244da161ff032f06ac8731db8ee
https://doi.org/10.1128/jvi.01034-07
https://doi.org/10.1128/jvi.01034-07
Autor:
Amit Verma, Li Zhou, Tony A. Navas, Simrit Parmar, Perry Pahanish, Linda S. Higgins, Jing Ying Ma, Yin Xu, Myka Estes, Lubomir Sokol, Aaron N. Nguyen, A. List, Leonidas C. Platanias, Mani Mohindru, Edwin Haghnazari, Irene Kerr, Robert H. Collins
Publikováno v:
Blood. 108:4170-4177
The myelodysplastic syndromes (MDSs) are collections of heterogeneous hematologic diseases characterized by refractory cytopenias as a result of ineffective hematopoiesis. Development of effective treatments has been impeded by limited insights into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6089cf63c197a2ad721ebe99a9f52e97
https://doi.org/10.1182/blood-2006-05-023093
https://doi.org/10.1182/blood-2006-05-023093
Publikováno v:
European Journal of Immunology. 34:2730-2739
Theiler's murine encephalomyelitis virus (TMEV) infection of the CNS induces an immune-mediated demyelinating disease in susceptible mouse strains and serves as a relevant infection model for human multiple sclerosis. However, it is not yet clear wha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b37c9c47d75f4740e56af23a5e1dab3
https://doi.org/10.1002/eji.200324811
https://doi.org/10.1002/eji.200324811
Autor:
Michael A. Lyman, Joann P. Palma, Mani Mohindru, Hee-Kap Kang, Byung S. Kim, Hee-Gu Lee, Bongsu Kang
Publikováno v:
Immunologic Research
Theiler's murine encephalomyelitis virus-induced demyelinating disease has been extensively studied as an attractive infectious model for human multiple sclerosis. Virus-specific inflammatory Th1 cell responses followed by autoimmune responses to mye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bffca374aa7a25124007d2dcd46954
http://europepmc.org/articles/PMC7091353
http://europepmc.org/articles/PMC7091353
Publikováno v:
The Journal of Immunology. 165:583-590
Intracerebral infection of susceptible mice with Theiler’s murine encephalomyelitis virus results in immune-mediated inflammatory demyelination in the white matter and consequent clinical symptoms. This system has been utilized as an important viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695d0082834a4088a06acb5dd22d937e
https://doi.org/10.4049/jimmunol.165.1.583
https://doi.org/10.4049/jimmunol.165.1.583
Autor:
Amit Verma, Mani Mohindru
Publikováno v:
Indian journal of pediatrics. 72(11)
Over the last two decades cancer cure rates have not gone up as expected, and the effectiveness of chemotherapy has reached a plateau. This has prompted a search for targeted therapies with higher efficacy and lesser toxicities. Monoclonal antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cba424eab976c32d1719023886c92ca
https://pubmed.ncbi.nlm.nih.gov/16391449
https://pubmed.ncbi.nlm.nih.gov/16391449
Autor:
Rosemarie H. DeKruyff, Byung S. Kim, Anthony J. Coyle, William J. Simmons, Scott Cutro, Parul Singh, Giorgio Inghirami, Nicholas M. Ponzio, Rajan M. Thomas, Mythili Koneru, Mani Mohindru
Although T cells infiltrate many types of murine and human neoplasms, in many instances tumor-specific cytotoxicity is not observed. Strategies to stimulate CTL-mediated antitumor immunity have included in vitro stimulation and/or genetic engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eff5f9508de9890c6c7cc0d399056bc
http://hdl.handle.net/2318/42436
http://hdl.handle.net/2318/42436
Autor:
Amit Verma, Mani Mohindru
Publikováno v:
Indian journal of pediatrics. 71(8)
Genetic mutations can lead to abnormal activation of certain kinases that in turn lead to excessive cell division seen in cancers. Inhibitors of over activated kinases can theoretically inhibit cancer causing pathways and result in tumor shrinkage. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e253c82c03fa51fce9fa7ffe1071072a
https://pubmed.ncbi.nlm.nih.gov/15345872
https://pubmed.ncbi.nlm.nih.gov/15345872
Publikováno v:
Journal of neuroimmunology. 155(1-2)
Experimental autoimmune encephalomyelitis (EAE) is a widely adopted animal model system for studying human multiple sclerosis that affects the central nervous system (CNS). To understand the underlying pathogenic mechanisms of the autoimmune T cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f44efcd3a68aaf9443e1beb3201da5
https://pubmed.ncbi.nlm.nih.gov/15342203
https://pubmed.ncbi.nlm.nih.gov/15342203