Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape

Autor: Mangolini, Maurizio, Maiques-Diaz, Alba, Charalampopoulou, Stella, Gerhard-Hartmann, Elena, Bloehdorn, Johannes, Moore, Andrew, Giachetti, Giorgia, Lu, Junyan, Roamio Franklin, Valar Nila, Chilamakuri, Chandra Sekkar Reddy, Moutsopoulos, Ilias, Rosenwald, Andreas, Stilgenbauer, Stephan, Zenz, Thorsten, Mohorianu, Irina, D'Santos, Clive, Deaglio, Silvia, Hodson, Daniel J, Martin-Subero, Jose I, Ringshausen, Ingo

Hotspot mutations in the PEST-domain of NOTCH1 and NOTCH2 are recurrently identified in B cell malignancies. To address how NOTCH-mutations contribute to a dismal prognosis, we have generated isogenic primary human tumor cells from patients with Chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11899aea8fad9f4ca973b6120f75a29

STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia

Autor: Mangolini, Maurizio, de Boer, Jasper, Walf-Vorderwülbecke, Vanessa, Pieters, Rob, den Boer, Monique L., Williams, Owen ^*

Publikováno v: In Blood 25 July 2013 122(4):542-549

Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance

Autor: Park, Eugene, Chen, Jingyu, Moore, Andrew, Mangolini, Maurizio, Santoro, Antonella, Boyd, Joseph, Schjerven, Hilde, Ecker, Veronika, Buchner, Maike, Williamson, James, Lehner, Paul, Gasparoli, Luca, Williams, Owen, Bloehdorn, Johannes, Stilgenbauer, Stephan, Leitges, Michael, Egle, Alexander, Schmidt-Supprian, Marc, Frietze, Seth, Ringshausen, Ingo

Publikováno v: Park, Eugene Chen, Jingyu Moore, Andrew Mangolini, Maurizio Santoro, Antonella Boyd, Joseph Schjerven, Hilde Ecker, Veronika Buchner, Maike Williamson, James Lehner, Paul Gasparoli, Luca Williams, Owen Bloehdorn, Johannes Stilgenbauer, Stephan Leitges, Michael Egle, Alexander Schmidt-Supprian, Marc Frietze, Seth Ringshausen, Ingo . Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance. Science Translational Medicine. 2020, 12:eaax9340(526), 1-17
Science Translational Medicine

Externí odkaz: http://hdl.handle.net/10852/82995
https://www.duo.uio.no/bitstream/handle/10852/82995/2/Postnr%2B1844450_Sci%2BTransl%2BMed_Schjerven.pdf

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CRISPR-Cas9 Genome Editing of Primary Chronic Lymphocytic Leukemia Cells

Autor: Mateos-Jaimez, Judith ^*, Mangolini, Maurizio ^*, Vidal, Anna ^*, Colomer, Dolors ^*, Campo, Elías, Ringshausen, Ingo, Martín-Subero, José I. ^*, Maiques-Diaz, Alba ^*

Publikováno v: In Blood 15 November 2022 140 Supplement 1:9849-9850