Licogliflozin for nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a study.

Autor: Harrison SA; Pinnacle Clinical Research, San Antonio, Texas, USA. sharrison@pinnacleresearch.com., Manghi FP; CINME, Buenos Aires, Argentina., Smith WB; Alliance for Multispecialty Research, The University of Tennessee Medical Center, Knoxville, TN, USA., Alpenidze D; City Outpatient Clinic #117, St. Petersburg, Russia., Aizenberg D; Centro Medico Viamonte, Buenos Aires, Argentina., Klarenbeek N; Centre for Human Drug Research, Leiden, the Netherlands., Chen CY; Chia-Yi Christian Hospital, Chiayi City, Taiwan., Zuckerman E; Carmel Medical Center, Haifa, Israel., Ravussin E; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Charatcharoenwitthaya P; Siriraj Hospital, Bangkok, Thailand., Cheng PN; National Cheng Kung University Hospital, Tainan City, Taiwan., Katchman H; Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Klein S; Washington University School of Medicine, St. Louis, MO, USA., Ben-Ari Z; Sheba Medical Center, Ramat Gan, Israel., Mendonza AE; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Zhang Y; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Martic M; Novartis Institutes for BioMedical Research, Basel, Switzerland., Ma S; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Kao S; Novartis Institutes for BioMedical Research, Pudong Shanghai, China., Tanner S; Novartis Institutes for BioMedical Research, Basel, Switzerland., Pachori A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Badman MK; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., He Y; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Ukomadu C; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Sicard E; Altasciences Algorithme Pharma, Quebec, Canada.

Publikováno v: Nature medicine [Nat Med] 2022 Jul; Vol. 28 (7), pp. 1432-1438. Date of Electronic Publication: 2022 Jun 20.