Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Structure-Based Design of a Chemical Probe Set for the 5‑HT5A Serotonin Receptor.

Autor: Levit Kaplan, Anat, Strachan, Ryan T., Braz, Joao M., Craik, Veronica, Slocum, Samuel, Mangano, Thomas, Amabo, Vanessa, O'Donnell, Henry, Lak, Parnian, Basbaum, Allan I., Roth, Bryan L., Shoichet, Brian K.

Publikováno v: Journal of Medicinal Chemistry; 3/10/2022, Vol. 65 Issue 5, p4201-4217, 17p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Potent, Selective, and Cell-active Chemical Probe of Protein Lysine Methyltransferases G9a and GLP: Cell-Based Assays

Autor: Dalia Baryste-Lovejoy, Sylvie Rival-Gervier, Feng Liu, Abdellah Allali-Hassani, Wigle, Tim J., Dimaggio, Peter A., Gregory, A. Wasney, Alena Siarheyeva, Aiping Dong, Wolfram Tempel, Xin Chen, Irene Chau, Mangano, Thomas J., Evans, Jon M., Simpson, Catherine D., Samantha, G. Pattenden, Norris, Jacqueline L., Kireev, Dmitri B., Ashutosh Tripathy, Aled Edwards, Bryan Roth, Janzen, William P., Garcia, Benjamin A., Brown, Petyer J., Frye, Stephen V., Masoud Vedadi, James Ellis, Jian Jin, Arrowsmith, Cheryl H.

Publikováno v: 2. Oxford Symposium on "Epigenetic Mechanisms in Health and Disease"-"Role of chromatin modifications in inflammation"
2. Oxford Symposium on "Epigenetic Mechanisms in Health and Disease"-"Role of chromatin modifications in inflammation", Dec 2010, Oxford, United Kingdom
HAL

International audience; Histone lysine methylation is important epigenetic mark that regulates chromatin structure and gene expression. G9a and GLP lysine methyltransferases dimethylate lysine 9 on histone H3 and repress gene transcription playing ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::603ba2e8d93ce6e1b368dc58f8974a62
https://hal.inrae.fr/hal-02823689

Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor.

Autor: Zhong Zheng, Xi-Ping Huang, Mangano, Thomas J., Rodger Zou, Xin Chen, Zaidi, Saheem A., Roth, Bryan L., Stevens, Raymond C., Katritch, Vsevolod

Publikováno v: Journal of Medicinal Chemistry; 4/13/2017, Vol. 60 Issue 7, p3070-3081, 12p