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Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients.

Autor: Stern S; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA. sstern@univ.haifa.ac.il.; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel. sstern@univ.haifa.ac.il., Lau S; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Manole A; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Rosh I; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Percia MM; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Ben Ezer R; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Shokhirev MN; Razavi Newman Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA, USA., Qiu F; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Schafer S; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA.; Department of Psychiatry, School of Medicine, Technical University of Munich, Munich, Germany., Mansour AA; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA.; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Mangan KP; Fujifilm Cellular Dynamics, In, Madison, WI, 53711, USA., Stern T; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA.; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Ofer P; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA.; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Stern Y; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA.; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Diniz Mendes AP; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Djamus J; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Moore LR; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Nayak R; Sagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Laufer SH; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Aicher A; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Rhee A; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Wong TL; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Nguyen T; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Linker SB; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA., Winner B; Department of Stem Cell Biology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuernberg, Erlangen, Germany., Freitas BC; Fujifilm Cellular Dynamics, In, Madison, WI, 53711, USA., Jones E; Fujifilm Cellular Dynamics, In, Madison, WI, 53711, USA., Sagi I; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Bardy C; South Australian Health and Medical Research Institute (SAHMRI), Laboratory for Human Neurophysiology and Genetics, Adelaide, SA, Australia.; Flinders University, Flinders Health and Medical Research Institute (FHMRI), Adelaide, SA, Australia., Brice A; Sorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, Inserm, CNRS, APHP, F-75013, Paris, France., Winkler J; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen- Nürnberg, Nürnberg, Germany., Marchetto MC; Department of Anthropology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA., Gage FH; Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA, USA. gage@salk.edu.

Publikováno v: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2022 Aug 10; Vol. 8 (1), pp. 103. Date of Electronic Publication: 2022 Aug 10.

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo.

Autor: Wakeman DR; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA. Electronic address: dwakeman@rx-gen.com., Hiller BM; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA., Marmion DJ; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA., McMahon CW; Cellular Dynamics International: A Fujifilm Company, Madison, WI 53711, USA., Corbett GT; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA., Mangan KP; Cellular Dynamics International: A Fujifilm Company, Madison, WI 53711, USA., Ma J; Cellular Dynamics International: A Fujifilm Company, Madison, WI 53711, USA., Little LE; Cellular Dynamics International: A Fujifilm Company, Madison, WI 53711, USA., Xie Z; Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA., Perez-Rosello T; Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA., Guzman JN; Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA., Surmeier DJ; Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA., Kordower JH; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA; The Van Andel Institute, Grand Rapids, MI 49503, USA. Electronic address: jkordowe@rush.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2017 Jul 11; Vol. 9 (1), pp. 149-161. Date of Electronic Publication: 2017 Jun 01.

NMDA and dopamine converge on the NMDA-receptor to induce ERK activation and synaptic depression in mature hippocampus.

Autor: Kaphzan H; Center for Brain and Behavior, Department of Neurobiology and Ethology, Haifa University, Haifa, Israel., O'Riordan KJ, Mangan KP, Levenson JM, Rosenblum K

Publikováno v: PloS one [PLoS One] 2006 Dec 27; Vol. 1, pp. e138. Date of Electronic Publication: 2006 Dec 27.