Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mangala Samy"'
Publikováno v:
Experimental and Molecular Pathology. 68:65-69
We previously conducted a study of 88 cases of prostate cancer in an attempt to identify potential prognostic biomarkers that can distinguish aggressive cases that must be treated immediately. Prostate cancer is a serious disease affecting men worldw
Publikováno v:
Experimental and Molecular Pathology. 67:109-117
In a previous study, we observed a low frequency of HER-2/neu oncogene amplification in prostate cancer using fluorescent in situ hybridization (FISH). In our continued effort to identify prognostic biomarkers in prostate cancer, we analyzed 74 cases
Publikováno v:
Experimental and Molecular Pathology. 66:170-178
Prostate cancer is a serious disease affecting men worldwide and treatment compromises the quality of life of prostate cancer patients. We conducted a study of 88 cases of prostate cancer in an attempt to identify prognostic biomarkers that can disti
Publikováno v:
Experimental and Molecular Pathology. 66:157-162
Cervical carcinoma is a malignancy which typically occurs at the transformation zone between squamous and glandular epithelium. The vast majority falls into two histologic types, squamous cell and adenocarcinoma. In an effort to identify a subset of
Autor:
Stephen Brown, William Taylor, Kirby I. Bland, Hon Fong L. Mark, Mangala Samy, Kathleen Santoro, Ci-Lin Sun
Publikováno v:
Cancer Genetics and Cytogenetics. 108:1-5
To test the hypothesis that the frequency of abnormal chromosome 8 copy number increases with the severity of the disease as defined by an increase in clinical stage, we conducted a fluorescence in situ hybridization (FISH) study of a sample of 42 br
Autor:
Stephen Brown, William Taylor, Ping H Hsu, Mangala Samy, Kathleen Zolnierz, Kirby I. Bland, Nader Bassily, Ci-Lin Sun, Bassam I. Aswad, Hon Fong L. Mark, Edith Wong
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 1(3)
Purpose: Approximately 25–30% of breast and ovarian carcinomas have amplification of the HER-2/neu oncogene. The aim of the present study was to focus on HER-2/neu gene amplification in different clinical stages of breast cancer in order to (1) det
Publikováno v:
Genetic testing. 3(2)
Oncogene amplification, such as HER-2/neu (C-erbB-2), is a manifestation of genetic instability often associated with the genesis and progression of cancer, including cervical cancer. Oncogene overexpression is traditionally studied using immunohisto
Publikováno v:
Experimental and molecular pathology. 66(1)
Ovarian cancer is the leading cause of death from gynecologic maligancy among women in the United States. In 1997, there were nearly 27,000 ovarian cancer cases with over 14,000 deaths. Recent attempts at early detection of ovarian cancer have been a
Autor:
William Taylor, Mangala Samy, Nader Bassily, Stephen Brown, Ci-Lin Sun, Kirby I. Bland, Hon Fong L. Mark
Publikováno v:
Cancer genetics and cytogenetics. 108(1)
Trisomy 12 is the most frequent numerical chromosomal abnormality reported in chronic lymphocytic leukemia (CLL). Its significance in other cancers, however, has not been extensively investigated until recently. Less than 20 cases of polysomy for chr
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 66(2)
Embryonal rhabdomyosarcoma is the most common malignant soft-tissue tumor in childhood, comprising 45–50% of childhood sarcomas. Cytogenetic studies of this tumor are rare. In view of the paucity of cytogenetic data on this cancer and based on the