Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mangala Hegde"'
Autor:
Babu Santha Aswani, Mangala Hegde, Ravichandran Vishwa, Mohammed S. Alqahtani, Mohamed Abbas, Hassan Ali Almubarak, Gautam Sethi, Ajaikumar B. Kunnumakkara
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-39 (2024)
Abstract Nuclear receptors (NRs) function as crucial transcription factors in orchestrating essential functions within the realms of development, host defense, and homeostasis of body. NRs have garnered increased attention due to their potential as t
Externí odkaz:
https://doaj.org/article/fff136fccb7041f48f03d158c36f1e3d
Autor:
Maniyamma Aswathy, Dey Parama, Mangala Hegde, Sherin DR, Ravi S. Lankalapalli, Kokkuvayil Vasu Radhakrishnan, Ajaikumar B. Kunnumakkara
Publikováno v:
ACS Omega, Vol 9, Iss 23, Pp 24252-24267 (2024)
Externí odkaz:
https://doaj.org/article/62c4307b7f184f1581248d9acfa9afe7
Publikováno v:
Integrative Medicine Research, Vol 12, Iss 3, Pp 100968- (2023)
Background: Despite the extensive research in recent years, the current treatment modalities for neurological disorders are suboptimal. Curcumin, a polyphenol found in Curcuma genus, has been shown to mitigate the pathophysiology and clinical sequala
Externí odkaz:
https://doaj.org/article/641724568b284040858c0896bf0405d4
Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far?
Autor:
Nikunj Naliyadhara, Aviral Kumar, Shailendra Kumar Gangwar, Thulsidharan Nair Devanarayanan, Mangala Hegde, Mohammed S. Alqahtani, Mohamed Abbas, Gautam Sethi, Ajaikumar Kunnumakkara
Publikováno v:
Journal of Functional Foods, Vol 100, Iss , Pp 105365- (2023)
The human gastrointestinal tract harbors a diverse range of microbial species, which helps to regulate various biological processes such as homeostasis of the gut barrier, stimulation of the immune system, and neurological health benefits from the gu
Externí odkaz:
https://doaj.org/article/04e18e489610419baa6e43851cc85cf2
Autor:
Aviral Kumar, Sosmitha Girisa, Mohammed S. Alqahtani, Mohamed Abbas, Mangala Hegde, Gautam Sethi, Ajaikumar B. Kunnumakkara
Publikováno v:
Cells, Vol 12, Iss 5, p 810 (2023)
Cancer has become a global health hazard accounting for 10 million deaths in the year 2020. Although different treatment approaches have increased patient overall survival, treatment for advanced stages still suffers from poor clinical outcomes. The
Externí odkaz:
https://doaj.org/article/7b64720c9cec488b9bb7f6a1ac9e9ee4
Autor:
Mangala Hegde, Uzini Devi Daimary, Sandra Jose, Anjana Sajeev, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Mehdi Shakibaei, Ajaikumar B. Kunnumakkara
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Regulation of intracellular concentration of calcium levels is crucial for cell signaling, homeostasis, and in the pathology of diseases including cancer. Agonist-induced entry of calcium ions into the non-excitable cells is mediated by store-operate
Externí odkaz:
https://doaj.org/article/e7b72d69aa1d46ffb735065ab6b9ae2d
Autor:
Sujitha Jayaprakash, Mangala Hegde, Bandari BharathwajChetty, Sosmitha Girisa, Mohammed S. Alqahtani, Mohamed Abbas, Gautam Sethi, Ajaikumar B. Kunnumakkara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12380 (2022)
Cancer is a deadly disease worldwide, with an anticipated 19.3 million new cases and 10.0 million deaths occurring in 2020 according to GLOBOCAN 2020. It is well established that carcinogenesis and cancer development are strongly linked to genetic ch
Externí odkaz:
https://doaj.org/article/6389db27a1a8475ea68b8fb9365aa182
Autor:
Sujitha Jayaprakash, Mangala Hegde, Sosmitha Girisa, Mohammed S. Alqahtani, Mohamed Abbas, E. Hui Clarissa Lee, Kenneth Chun-Hong Yap, Gautam Sethi, Alan Prem Kumar, Ajaikumar B. Kunnumakkara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10952 (2022)
Esophageal cancer (EC), an aggressive and poorly understood disease, is one of the top causes of cancer-related fatalities. GLOBOCAN 2020 reports that there are 544,076 deaths and 604,100 new cases expected worldwide. Even though there are various ad
Externí odkaz:
https://doaj.org/article/4faaf36427c04e65951c386406c75147
Autor:
Anjana Sajeev, Mangala Hegde, Sosmitha Girisa, Thulasidharan Nair Devanarayanan, Mohammed S. Alqahtani, Mohamed Abbas, Samir Kumar Sil, Gautam Sethi, Jen-Tsung Chen, Ajaikumar B. Kunnumakkara
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1185 (2022)
There have been magnificent advancements in the understanding of molecular mechanisms of chronic diseases over the past several years, but these diseases continue to be a considerable cause of death worldwide. Most of the approved medications availab
Externí odkaz:
https://doaj.org/article/eeca482b3c574d948b387ba5a5dfe288
Publikováno v:
Çukurova Üniversitesi Tıp Fakültesi Dergisi, Vol 40, Iss 3, Pp 510-516 (2015)
Purpose: The initial stage of proliferation of epithelial ovarian carcinoma (EOCa) is usually asymptomatic. Due to the lack of sensitive and reliable markers in majority of patients the disease is widespread at the time of diagnosis. The reliable ser
Externí odkaz:
https://doaj.org/article/f3ab0146f874429e9f5b13f9661a8ce2