Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Mangala, Rao"'
Publikováno v:
Journal of Medical Sciences and Health, Vol 9, Iss 3, Pp 274-280 (2023)
Introduction: Withania somnifera (WS)/Ashwagandha is well-known as an anti-stressor. Although the active constituents are present in the entire plant, only roots are used. Thus, our aim was to evaluate the physical endurance enhancing capacity of the
Externí odkaz:
https://doaj.org/article/3c09500e75ae4e46b752259e10388ead
Autor:
Swati Jain, Gherman Uritskiy, Marthandan Mahalingam, Himanshu Batra, Subhash Chand, Hung V Trinh, Charles Beck, Woong-Hee Shin, Wadad Alsalmi, Gustavo Kijak, Leigh A Eller, Jerome Kim, Daisuke Kihara, Sodsai Tovanabutra, Guido Ferrari, Merlin L Robb, Mangala Rao, Venigalla B Rao
Publikováno v:
eLife, Vol 13 (2024)
A productive HIV-1 infection in humans is often established by transmission and propagation of a single transmitted/founder (T/F) virus, which then evolves into a complex mixture of variants during the lifetime of infection. An effective HIV-1 vaccin
Externí odkaz:
https://doaj.org/article/67dbb3b3745540c7a92cab8a513f8bfe
Autor:
Erwin G. Abucayon, Ilya Belikow-Crovetto, Elizabeth Hussin, Jiae Kim, Gary R. Matyas, Mangala Rao, Carl R. Alving
Publikováno v:
Vaccines, Vol 12, Iss 6, p 681 (2024)
Particulate aluminum salts have long occupied a central place worldwide as inexpensive immunostimulatory adjuvants that enable induction of protective immunity for vaccines. Despite their huge benefits and safety, the particulate structures of alumin
Externí odkaz:
https://doaj.org/article/92a0c28df6c14455981c7a47bb9dfdfd
Autor:
Shikha Shrivastava, Joshua M. Carmen, Zhongyan Lu, Shraddha Basu, Rajeshwer S. Sankhala, Wei-Hung Chen, Phuong Nguyen, William C. Chang, Jocelyn King, Courtney Corbitt, Sandra Mayer, Jessica S. Bolton, Alexander Anderson, Isabella Swafford, Guillermo D. Terriquez, Hung V. Trinh, Jiae Kim, Ousman Jobe, Dominic Paquin-Proulx, Gary, R. Matyas, Gregory D. Gromowski, Jeffrey R. Currier, Elke Bergmann-Leitner, Kayvon Modjarrad, Nelson L. Michael, M. Gordon Joyce, Allison M. W. Malloy, Mangala Rao
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with eithe
Externí odkaz:
https://doaj.org/article/d8f58b2e3b264c9caf318f2cc61ee799
Autor:
Margaret C. Costanzo, Dominic Paquin-Proulx, Alexandra Schuetz, Siriwat Akapirat, Zhanna Shubin, Dohoon Kim, Lindsay Wieczorek, Victoria R. Polonis, Hung V. Trinh, Mangala Rao, Hanna Anenia, Michael D. Barrera, Jacob Boeckelman, Barbara Nails, Pallavi Thapa, Michelle Zemil, Carlo Sacdalan, Eugene Kroon, Boot Kaewboon, Somporn Tipsuk, Surat Jongrakthaitae, Sanjay Gurunathan, Faruk Sinangil, Jerome H. Kim, Merlin L. Robb, Julie A. Ake, Robert J. O’Connell, Punnee Pitisutthithum, Sorachai Nitayaphan, Suwat Chariyalertsak, Michael A. Eller, Nittaya Phanuphak, Sandhya Vasan, the RV, RV328 study groups
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
The RV144 phase III vaccine trial demonstrated that ALVAC-HIV and AIDSVAX B/E administration over 6 months resulted in 31% efficacy in preventing HIV acquisition, while administration of AIDSVAX B/E alone in both VAX003 and VAX004 studies failed to s
Externí odkaz:
https://doaj.org/article/54ea0fbbfd224eb79d9efe0dfded1c6a
Autor:
Shraddha Basu, Neelakshi Gohain, Jiae Kim, Hung V. Trinh, Misook Choe, M. Gordon Joyce, Mangala Rao
Publikováno v:
Cells, Vol 13, Iss 1, p 33 (2023)
Developing a preventative vaccine for HIV-1 has been a global priority. The elicitation of broadly neutralizing antibodies (bNAbs) against a broad range of HIV-1 envelopes (Envs) from various strains appears to be a critical requirement for an effica
Externí odkaz:
https://doaj.org/article/94b557cde4d44f99a6f099511f0e68ac
Autor:
Ousman Jobe, Jiae Kim, Daniel O. Pinto, Zuzana Villar, Tiffany Hewitt, Elizabeth H. Duncan, Alexander Anderson, Neelakshi Gohain, Hua Gong, Courtney Tucker, Carl R. Alving, Gary R. Matyas, Elke Bergmann-Leitner, Mangala Rao
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Monocyte-derived macrophages (MDM) are highly permissive to HIV-1 infection potentially due to the downregulation of innate factors during the differentiation process. The environmental milieu and innate anti-viral factors which are modulate
Externí odkaz:
https://doaj.org/article/ef40e36554704102ab59c56962ea9f39
Autor:
Mohammad Arif Rahman, Manuel Becerra-Flores, Yury Patskovsky, Isabela Silva de Castro, Massimiliano Bissa, Shraddha Basu, Xiaoying Shen, LaTonya D. Williams, Sarkis Sarkis, Kombo F. N’guessan, Celia LaBranche, Georgia D. Tomaras, Pyone Pyone Aye, Ronald Veazey, Dominic Paquin-Proulx, Mangala Rao, Genoveffa Franchini, Timothy Cardozo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAn efficacious HIV vaccine will need to elicit a complex package of innate, humoral, and cellular immune responses. This complex package of responses to vaccine candidates has been studied and yielded important results, yet it has been a
Externí odkaz:
https://doaj.org/article/f271626acd674386b239c0823d800dfb
Autor:
Nimisha Rikhi, Clara J. Sei, Mangala Rao, Richard F. Schuman, Kellie A. Kroscher, Gary R. Matyas, Kevin Muema, Camille Lange, Aba Assiaw-Dufu, Elizabeth Hussin, Ousman Jobe, Carl R. Alving, Gerald W. Fischer
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1468 (2023)
An unconjugated composite peptide vaccine targeting multiple conserved influenza epitopes from hemagglutinin, neuraminidase, and matrix protein and formulated with a safe and highly potent adjuvant, Army Liposome formulation (ALFQ), generated broad a
Externí odkaz:
https://doaj.org/article/dac232adba314c65a967ca9b2e8b7a16
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2212 (2023)
Army Liposome Formulation with QS21 (ALFQ), a vaccine adjuvant preparation, comprises liposomes containing saturated phospholipids, with 55 mol% cholesterol relative to the phospholipids, and two adjuvants, monophosphoryl lipid A (MPLA) and QS21 sapo
Externí odkaz:
https://doaj.org/article/257731d26196415ea562039715e13264