Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Manfrid Eltze"'
Autor:
Manfrid Eltze, Christoph Stoll, Josef Zentner, Thomas J. Feuerstein, Rolf Jackisch, Günter Lambrecht
Publikováno v:
Journal of Neurochemistry. 110:837-847
Electrically evoked overflow of [(3)H]acetylcholine in slices of rat neocortex and of human neocortex (freshly obtained during neurosurgical treatment of epilepsy or deep-seated tumors) was used to functionally characterize the muscarinic receptor su
Autor:
Rudolf Lucas, Albrecht Wendel, Andreas Strub, Clemens Braun, Thomas Grebe, Manfrid Eltze, Jürg Hamacher, Katja Eichert
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 20:525-533
The cysteinyl leukotrienes (CysLTs) LTC(4), LTD(4) and LTE(4) are potent proinflammatory lipid mediators that play a central role in inflammation, contraction and remodelling of airways observed in asthmatics. Montelukast, a competitive inhibitor of
Autor:
Wolf-Rüdiger Ulrich, Rainer Boer, Andreas Strub, Degenhard Marx, Christian Hesslinger, Manfrid Eltze, Martin Lehner, Ralph T. Schermuly, Frank Schwoebel, Johannes Barsig
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 317:181-187
Excessive release of nitric oxide from inducible nitric-oxide synthase (iNOS) has been postulated to contribute to pathology in a number of inflammatory diseases. We recently identified imidazopyridine derivatives as a novel class of potent nitricoxi
Publikováno v:
European journal of pharmacology, 443(1-3), 151-168. Elsevier
The present study examines the functional and binding affinities of the aporphine alkaloid, (+)-boldine, at different alpha(1)- and alpha(2)-adrenoceptor subtypes, namely, alpha(1A) (rat vas deferens and kidney) and its L-like state (rabbit spleen),
Autor:
Rodolfo Testa, Karl Sanders, Rainer Boer, Norbert Kolassa, Wolf-Rüdiger Ulrich, Peter Hein, Manfrid Eltze, Martin C. Michel
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 363:649-662
We have investigated the pharmacological properties of B8805-033 [(+/-)- 1,3,5-trimethyl-6-[[3-[4-((2,3-dihydro-2-hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl]propyl] amino]-2,4(1H,3H)-pyrimidinedione], a new alpha1A-adrenoceptor (AR) selective
Autor:
Manfrid Eltze
Publikováno v:
European Journal of Pharmacology. 295:69-73
The potency of the antipsychotic drug, risperidone, to antagonize alpha 1A-adrenoceptor-mediated contraction in rat vas deferens and vasoconstriction in rat perfused kidney, and alpha 1B-adrenoceptor-mediated contractions in spleen from guinea-pig an
Autor:
Manfrid Eltze
Publikováno v:
European Journal of Pharmacology. 260:211-220
A series of alpha 1-adrenoceptor agonists evoked concentration-dependent contraction of isolated guinea-pig spleen strips ((-)-adrenaline(-)-noradrenalineL-phenylephrine(-)-(4aR, 10aR)-3, 4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-methylthio-2H-nap
Publikováno v:
European Journal of Pharmacology. 211:283-293
The affinity of pizotifen, ketotifen and other tricyclic antimuscarinic drugs for different muscarinic receptor subtypes was investigated in vitro in functional experiments with field-stimulated vas deferens of the rabbit (M1 and M2 receptors) and wi
Publikováno v:
Cardiovascular research. 75(2)
Celecoxib carries a smaller cardiovascular risk for myocardial infarction and hypertension than other cyclooxygenase-2 (COX-2)-selective non-steroidal anti-inflammatory drugs NSAIDs ("coxibs") and may ameliorate endothelial dysfunction. We aimed to d
Autor:
Wolf-Rüdiger Ulrich, Christian Hesslinger, Andreas Strub, Manfrid Eltze, Martin Lehner, Thomas Fuchss, Rainer Boer
Publikováno v:
GBM Annual Spring meeting Mosbach 2006. 2006