Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Manfred W. Mueller"'
Autor:
Manfred W. Mueller, Wolfgang M. Schmidt, Olaf Bodamer, Wolfgang Maurer, Arnold Pollak, Georg Mitterer
Publikováno v:
Genetics in Medicine. 8:518-524
Purpose: Human mannose-binding lectin, encoded by the MBL2 gene, is an important component of innate immunity and an important regulator of inflammatory processes. MBL2 gene polymorphisms are associated with an increased risk of neonatal infections a
Autor:
Wolfgang M. Schmidt, Wolfgang Maurer, Olaf Bodamer, Manfred W. Mueller, Christian Harwanegg, Georg Mitterer
Publikováno v:
Genetic Testing. 9:6-13
The assessment of allelic variants in the human mannose-binding lectin 2 (MBL2) gene is of great clinical importance in newborns or immune-suppressed patients at high risk for a variety of infections. Here, we present a study on the genotyping accura
Autor:
Reinhard Hiller, Manfred W. Mueller, Helmut Rumpold, Christian Harwanegg, Nadja Balic, Karin Deinhofer, Susanne Spitzauer, Harald Sevcik
Publikováno v:
Methods. 32:249-254
Diagnosis of type I allergy is based on anamnesis, provocation testing, and serological determination of total and specific IgE. Currently, in vivo and in vitro diagnostic tests employ allergen extracts prepared from various allergen sources (e.g., p
Autor:
Robert M. Mader, Maria Kalipciyan, Guenther G. Steger, Wolfgang M. Schmidt, Eva Dornstauder, Roland Sedivy, Manfred W. Mueller, Blanka Rizovski
Publikováno v:
International Journal of Cancer. 112:200-212
Resistance to anticancer drugs such as the widely used antimetabolite 5-fluorouracil (FU) is one of the most important obstacles to cancer chemotherapy. Using GeneChip arrays, we compared the expression profile of different stages of FU resistance in
Publikováno v:
European Journal of Biochemistry. 269:175-183
A number of antibiotics have been reported to disturb the decoding process in prokaryotic translation and to inhibit the function of various natural ribozymes. We investigated the effect of several antibiotics on in vitro splicing of a eukaryotic nuc
Autor:
Wolfgang M. Schmidt, Manfred W. Mueller, Reinhard Hiller, Martin Huber, Doris Losert, Christian Harwanegg
Publikováno v:
Analytical Biochemistry. 299:24-30
DNA microarray technology holds significant promise for human DNA diagnostics. A number of technical approaches directed at the parallel identification of mutations or single nucleotide polymorphisms make use of polymerase-based specificity, like min
Autor:
Maren Hertweck, Manfred W. Mueller
Publikováno v:
European Journal of Biochemistry. 268:4610-4620
The function of group II introns depends on positively charged divalent metal ions that stabilize the ribozyme structure and may be directly involved in catalysis. We investigated Mn2+- and Zn2+-induced site-specific RNA cleavage to identify metal io
Publikováno v:
Nucleic Acids Research. 27:i-iv
Here we present CapSelect as a novel experimental approach for the selective enrichment of full-length cDNAs in PCR-mediated analysis of mRNA sequences. The method combines the 5'-CAP-dependent addition of specifically three to four non-templated dCM
A collection of papers by international contributors describing new developments in the fields of univariate and multivariate approximation theory. This research has applications in areas such as computer-aided geometric design, as applied in enginee
Publikováno v:
Nucleic Acids Research. 25:1825-1829
The excised group II intron bI1 from Saccharomyces cerevisiae can act as a ribozyme catalysing various chemical reactions with different substrate RNAs in vitro . Recently, we have described an editing-like RNA polymerization reaction catalysed by th