Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Manfred Thiel"'
Autor:
Franz-Simon Centner, Holger Wenz, Mariella Eliana Oster, Franz-Joseph Dally, Johannes Sauter-Servaes, Tanja Pelzer, Jochen J. Schoettler, Bianka Hahn, Amr Abdulazim, Katharian A. M. Hackenberg, Christoph Groden, Joerg Krebs, Manfred Thiel, Nima Etminan, Máté E. Maros
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectiveAlthough sepsis and delayed cerebral ischemia (DCI) are severe complications in patients with aneurysmal subarachnoid hemorrhage (aSAH) and share pathophysiological features, their interrelation and additive effect on functional outcome is u
Externí odkaz:
https://doaj.org/article/1dbe090cd1fe4bcd8143e73872749a98
Autor:
Jochen J. Schoettler, Kathrin Brohm, Sonani Mindt, Evelyn Jäger, Bianka Hahn, Tanja Fuderer, Holger A. Lindner, Verena Schneider-Lindner, Joerg Krebs, Michael Neumaier, Manfred Thiel, Franz-Simon Centner
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6391 (2024)
Tissue hypoxia is associated with the development of organ dysfunction and death in critically ill patients commonly captured using blood lactate. The kinetic parameters of serial lactate evaluations are superior at predicting mortality compared with
Externí odkaz:
https://doaj.org/article/cf9dc77cc8104e1ca38d7020510938cf
Autor:
Noah Schaefer, Holger A. Lindner, Bianka Hahn, Roman Schefzik, Sonia Y. Velásquez, Jutta Schulte, Tanja Fuderer, Franz-Simon Centner, Jochen J. Schoettler, Bianca S. Himmelhan, Timo Sturm, Manfred Thiel, Verena Schneider-Lindner, Anna Coulibaly
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPneumonia develops frequently after major surgery and polytrauma and thus in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation. Altered chec
Externí odkaz:
https://doaj.org/article/1e589a80bc8d4d3babb7041ad3e9a715
Autor:
André Luckscheiter, Wolfgang Zink, Torsten Lohs, Johanna Eisenberger, Manfred Thiel, Tim Viergutz
Publikováno v:
Clinical and Experimental Emergency Medicine, Vol 9, Iss 4, Pp 304-313 (2022)
Objective The aim of this study was to determine the feasibility of using machine learning to establish the need for preclinical airway management for injured patients based on a standardized emergency dataset. Methods A registry-based, retrospective
Externí odkaz:
https://doaj.org/article/9e6df92a7d00467aa8576df36bbd179d
Autor:
Peter T. Graf, Christoph Boesing, Isabel Brumm, Jonas Biehler, Kei Wieland Müller, Manfred Thiel, Paolo Pelosi, Patricia R. M. Rocco, Thomas Luecke, Joerg Krebs
Publikováno v:
Journal of Intensive Care, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Background Even an ultraprotective ventilation strategy in severe acute respiratory distress syndrome (ARDS) patients treated with extracorporeal membrane oxygenation (ECMO) might induce ventilator-induced lung injury and apneic ventilation
Externí odkaz:
https://doaj.org/article/e0b1628b39354ee8b46a649bafcd2e72
Autor:
Christoph Boesing, Peter T. Graf, Fabian Schmitt, Manfred Thiel, Paolo Pelosi, Patricia R. M. Rocco, Thomas Luecke, Joerg Krebs
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)
Abstract Background Prone positioning in combination with the application of low tidal volume and adequate positive end-expiratory pressure (PEEP) improves survival in patients with moderate to severe acute respiratory distress syndrome (ARDS). Howev
Externí odkaz:
https://doaj.org/article/313ba5feb30e45bf98fae9a4a33b8f08
Autor:
Franz-Simon Centner, Jochen J. Schoettler, Kathrin Brohm, Sonani Mindt, Evelyn Jäger, Bianka Hahn, Tanja Fuderer, Holger A. Lindner, Verena Schneider-Lindner, Joerg Krebs, Michael Neumaier, Manfred Thiel
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12600 (2023)
A common final pathway of pathogenetic mechanisms in septic organ dysfunction and death is a lack or non-utilization of oxygen. Plasma concentrations of lactate serve as surrogates for the oxygen-deficiency-induced imbalance between energy supply and
Externí odkaz:
https://doaj.org/article/4b1fb4b7ac5848efbee902653baf5b17
Autor:
Matthias Otto, Yannik Kropp, Evelyn Jäger, Michael Neumaier, Manfred Thiel, Michael Quintel, Charalambos Tsagogiorgas
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2080 (2023)
Mechanically ventilated patients suffering from acute respiratory distress syndrome (ARDS) frequently receive aerosolized iloprost. Because of prostacyclin’s short half-life, prolonged inhalative administration might improve its clinical efficacy.
Externí odkaz:
https://doaj.org/article/0090a898fc064002b5375be9eabd8afc
Autor:
Holger A. Lindner, Shigehiko Schamoni, Thomas Kirschning, Corinna Worm, Bianka Hahn, Franz-Simon Centner, Jochen J. Schoettler, Michael Hagmann, Jörg Krebs, Dennis Mangold, Stephanie Nitsch, Stefan Riezler, Manfred Thiel, Verena Schneider-Lindner
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-29 (2022)
Abstract Background Sepsis is the leading cause of death in the intensive care unit (ICU). Expediting its diagnosis, largely determined by clinical assessment, improves survival. Predictive and explanatory modelling of sepsis in the critically ill co
Externí odkaz:
https://doaj.org/article/00a8f5f55123409eb3c092c30ed73552
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Assessment of microcirculatory functional capacity is considered to be of prime importance for therapy guidance and outcome prediction in critically ill intensive care patients. Here, we show determination of skin microcirculatory oxygen del
Externí odkaz:
https://doaj.org/article/bff7917c212d450ebe8d8b16d8743c0a