Zobrazeno 1 - 10
of 838
pro vyhledávání: '"Manfred P. Wirth"'
Autor:
Michael Froehner, Rainer Koch, Ulrike Heberling, Angelika Borkowetz, Matthias Hübler, Vladimir Novotny, Manfred P. Wirth, Christian Thomas
Publikováno v:
European Urology Open Science, Vol 29, Iss , Pp 15-18 (2021)
Life expectancy is increasing in many parts of the world. Using proportional hazard models for competing risks, we investigated whether this increase has changed outcomes after radical cystectomy in a sample of 1419 consecutive patients treated betwe
Externí odkaz:
https://doaj.org/article/15e94b6d9bd64a77bc820df482eb32af
Autor:
Michael Froehner, Rainer Koch, Matthias Hübler, Ulrike Heberling, Vladimir Novotny, Stefan Zastrow, Oliver W. Hakenberg, Manfred P. Wirth
Publikováno v:
BMC Urology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Radical cystectomy bears a considerable perioperative mortality risk particularly in elderly patients. In this study, we searched for predictors of perioperative and long-term competing (non-bladder cancer) mortality in elderly pa
Externí odkaz:
https://doaj.org/article/8cad121b81434310ae1f8a48f70e5108
Autor:
Markus Friedemann, Friederike Horn, Katharina Gutewort, Lars Tautz, Carsten Jandeck, Nicole Bechmann, Olga Sukocheva, Manfred P. Wirth, Susanne Fuessel, Mario Menschikowski
Publikováno v:
Cancers, Vol 13, Iss 17, p 4459 (2021)
Identification of aberrant DNA methylation is a promising tool in prostate cancer (PCa) diagnosis and treatment. In this study, we evaluated a two-step method named optimised bias-based preamplification followed by digital PCR (OBBPA-dPCR). The metho
Externí odkaz:
https://doaj.org/article/c2b59d4caef643cea4cf25d574e88cd7
Autor:
Doreen Huebner, Christiane Rieger, Ralf Bergmann, Martin Ullrich, Sebastian Meister, Marieta Toma, Ralf Wiedemuth, Achim Temme, Vladimir Novotny, Manfred P. Wirth, Michael Bachmann, Jens Pietzsch, Susanne Fuessel
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches in animal models best possibly reflecting human disease before entering
Externí odkaz:
https://doaj.org/article/e4d4a9d9273b4e6d8aaeae60eba0d2d6
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 8, Iss 1, Pp 1307-1317 (2017)
We have previously shown that carbon nanofibers (CNFs) and carbon nanotubes (CNTs) can sensitize prostate cancer (PCa) cells to platinum-based chemotherapeutics. In order to further verify this concept and to avoid a bias, the present study investiga
Externí odkaz:
https://doaj.org/article/eb63cc11343740d2bd7cda1ec3a2d4da
Autor:
Angelika Borkowetz, Andrea Lohse-Fischer, Jana Scholze, Ulrike Lotzkat, Christian Thomas, Manfred P. Wirth, Susanne Fuessel, Kati Erdmann
Publikováno v:
Diagnostics, Vol 10, Iss 8, p 578 (2020)
Currently used tumor markers for early diagnosis of prostate cancer (PCa) are often lacking sufficient specificity and sensitivity. Therefore, the diagnostic potential of selected microRNAs in comparison to serum PSA levels and PSA density (PSAD) was
Externí odkaz:
https://doaj.org/article/7696d3a76b2746809b9602d543c685ef
Autor:
Kati Erdmann, Karsten Salomo, Anna Klimova, Ulrike Heberling, Andrea Lohse-Fischer, Romy Fuehrer, Christian Thomas, Ingo Roeder, Michael Froehner, Manfred P. Wirth, Susanne Fuessel
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3814 (2020)
Currently, voided urine cytology (VUC) serves as the gold standard for the detection of bladder cancer (BCa) in urine. Despite its high specificity, VUC has shortcomings in terms of sensitivity. Therefore, alternative biomarkers are being searched, w
Externí odkaz:
https://doaj.org/article/344f31e90ec64853b817c60fc0e82983
Autor:
Michael Rose, Sarah Bringezu, Laura Godfrey, David Fiedler, Nadine T. Gaisa, Maximilian Koch, Christian Bach, Susanne Füssel, Alexander Herr, Doreen Hübner, Jörg Ellinger, David Pfister, Ruth Knüchel, Manfred P. Wirth, Manja Böhme, Edgar Dahl
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1117 (2020)
Bladder cancer is one of the more common malignancies in humans and the most expensive tumor for treating in the Unites States (US) and Europe due to the need for lifelong surveillance. Non-invasive tests approved by the FDA have not been widely adop
Externí odkaz:
https://doaj.org/article/7b5aadcc26c2450fb79859d95de3acfc
Autor:
Michael Froehner, Marieta Toma, Klaus Zöphel, Vladimir Novotny, Michael Laniado, Manfred P. Wirth
Publikováno v:
Case Reports in Urology, Vol 2017 (2017)
A 67-year-old man diagnosed with Gleason score 4+5=9 clinically localized prostate cancer with 68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease
Externí odkaz:
https://doaj.org/article/ff31d7f7586542fa82c155419bf18704
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12297-12312 (2013)
The overexpression of antiapoptotic genes, such as Bcl-xL and survivin, contributes to the increased survival of tumor cells and to the development of treatment resistances. In the bladder cancer cell lines EJ28 and J82, the siRNA-mediated knockdown
Externí odkaz:
https://doaj.org/article/992875c45b544a209663cc6ebc08910a