Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Manfred Lindau"'
Autor:
Joannalyn B. Delacruz, Satyan Sharma, Shailendra Singh Rathore, Meng Huang, Joan S. Lenz, Manfred Lindau
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109580- (2021)
Summary: Many neurotransmitters are organic ions that carry a net charge, and their release from secretory vesicles is therefore an electrodiffusion process. The selectivity of early exocytotic fusion pores is investigated by combining electrodiffusi
Externí odkaz:
https://doaj.org/article/c8095224b4684a79971f49a0a4a9d2fe
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173993 (2017)
Although several proteins have been implicated in secretory vesicle tethering, the identity and mechanical properties of the components forming the physical vesicle-plasma membrane link remain unknown. Here we present the first experimental measureme
Externí odkaz:
https://doaj.org/article/50f0df93178e48908f64e0ba3fe3670a
Autor:
Madhurima Dhara, Antonio Yarzagaray, Mazen Makke, Barbara Schindeldecker, Yvonne Schwarz, Ahmed Shaaban, Satyan Sharma, Rainer A Böckmann, Manfred Lindau, Ralf Mohrmann, Dieter Bruns
Publikováno v:
eLife, Vol 5 (2016)
Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAR
Externí odkaz:
https://doaj.org/article/1e959e37992f4c52b003f93e4f9c8213
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144814 (2015)
The resemblance of lipid membrane models to physiological membranes determines how well molecular dynamics (MD) simulations imitate the dynamic behavior of cell membranes and membrane proteins. Physiological lipid membranes are composed of multiple t
Externí odkaz:
https://doaj.org/article/37d14b371e8944df9921c5ec041023f3
Autor:
Eugene V. Mosharov, Manfred Lindau
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071626702
Methods in Molecular Biology ISBN: 9781071626702
Both, patch amperometry (PA) and intracellular patch electrochemistry (IPE) take advantage of a recording configuration where an electrochemical detector – carbon fiber electrode (CFE) – is housed inside a patch pipette. PA, which is employed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40a8d5df2cc756028f25d502e32840b
https://europepmc.org/articles/PMC9910029/
https://europepmc.org/articles/PMC9910029/
Publikováno v:
Biophysical Journal. 122:461a-462a
Autor:
Shailendra Rathore, Manfred Lindau
Publikováno v:
Biophysical Journal. 122:517a
Publikováno v:
Journal of Neurochemistry
Neurodegenerative diseases, such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease, are considered incurable and significantly reduce the quality of life of the patients. A variety of drugs that modulate neurotransmitter lev
Autor:
Jonhoi Smith, Bradley A. Minch, Kevin A. White, Kiminobu Sugaya, Manfred Lindau, Geoffrey Mulberry, Brian N. Kim
Publikováno v:
IEEE Transactions on Biomedical Circuits and Systems. 12:1345-1355
Human neuroblastoma cells, SH-SY5Y, are often used as a neuronal model to study Parkinson's disease and dopamine release in the substantia nigra, a midbrain region that plays an important role in motor control. Using amperometric single-cell recordin
Publikováno v:
Analytical chemistry. 93(22)
Complementary metal-oxide-semiconductor (CMOS) microelectrode arrays integrate amplifier arrays with on-chip electrodes, offering high-throughput platforms for electrochemical sensing with high spatial and temporal resolution. Such devices have been