Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Manfred Kunz"'
Autor:
Maria Schmidt, Lena Sünke Mortensen, Henry Loeffler-Wirth, Corinna Kosnopfel, Knut Krohn, Hans Binder, Manfred Kunz
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 1, Pp 56-73 (2022)
Objective: Cellular heterogeneity is regarded as a major factor affecting treatment response and resistance in malignant melanoma. Recent developments in single-cell sequencing technology have provided deeper insights into these mechanisms. Methods:
Externí odkaz:
https://doaj.org/article/d97de2088572460aac8fa2d8e0788a40
Autor:
Anja Saalbach, Manfred Kunz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1291916861ca42d6a26d39ee62c448a1
Autor:
Benjamin Klein, Manfred Kunz
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Cutaneous lupus erythematosus (CLE) represents a complex autoimmune disease with a broad phenotypic spectrum ranging from acute to chronic destructive cutaneous lesions. Patients with CLE exhibit high photosensitivity and ultraviolet (UV) irradiation
Externí odkaz:
https://doaj.org/article/9976c3f649ff4b4981470a7d480e45dd
Autor:
Anja Saalbach, Manfred Kunz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Psoriasis is a chronic inflammatory disease of the skin and joints associated with several comorbidities such as arthritis, diabetes mellitus and metabolic syndrome, including obesity, hypertension and dyslipidaemia, Crohn’s disease, uveitis and ps
Externí odkaz:
https://doaj.org/article/615843889b07460e864dccc07d1f50af
Autor:
Christian Schwarm, Damian Gola, Maike M. Holtsche, Anabelle Dieterich, Anita Bhandari, Miriam Freitag, Peter Nürnberg, Mohammad Toliat, Wolfgang Lieb, Michael Wittig, André Franke, Margitta Worm, Michael Sticherling, Jan Ehrchen, Claudia Günther, Regine Gläser, Wiebke K. Peitsch, Miklós Sárdy, Rüdiger Eming, Michael Hertl, Sandrine Benoit, Matthias Goebeler, Claudia Pföhler, Manfred Kunz, Alexander Kreuter, Nina van Beek, Jeanette Erdmann, Hauke Busch, Detlef Zillikens, Christian D. Sadik, Misa Hirose, Inke R. König, Enno Schmidt, Saleh M. Ibrahim, German AIBD Study Group
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-5 (2021)
Abstract Bullous pemphigoid (BP) is the most common autoimmune skin blistering disease characterized by autoimmunity against the hemidesmosomal proteins BP180, type XVII collagen, and BP230. To elucidate the genetic basis of susceptibility to BP, we
Externí odkaz:
https://doaj.org/article/84efb268b4494d4bb022c88ca7f0f054
Autor:
Franziska Schauer, Alexander Nyström, Manfred Kunz, Stefanie Hübner, Sarah Scholl, Ioannis Athanasiou, Svenja Alter, Judith Fischer, Cristina Has, Dimitra Kiritsi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Collagen VII is the main constituent of the anchoring fibrils, important adhesive structures that attach the epidermis to the dermal extracellular matrix. Two disorders are caused by dysfunction of collagen VII, both characterized by skin and mucosa
Externí odkaz:
https://doaj.org/article/d7deab9ce12a4df7b69e4cb8ab9e9aca
Autor:
Julia Mentzel, Tabea Kynast, Johannes Kohlmann, Holger Kirsten, Matthias Blüher, Jan C. Simon, Manfred Kunz, Anja Saalbach
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Psoriasis is a chronic inflammatory disease of the skin and joints. More recent data emphasize an association with dysregulated glucose and fatty acid metabolism, obesity, elevated blood pressure and cardiac disease, summarized as metabolic syndrome.
Externí odkaz:
https://doaj.org/article/3f7aca90960748009dd1f95d8a6e63db
Autor:
Manfred Kunz
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/a87d54da41dd41e2bece5854d6be3a36
Publikováno v:
Clinical Case Reports, Vol 7, Iss 7, Pp 1347-1349 (2019)
Abstract Juvenile dermatomyositis shows characteristic skin lesions. However, this does not rule out co‐occurring other autoimmune diseases, which may be more prominent regarding skin manifestations. Co‐occurring other skin autoimmune diseases sh
Externí odkaz:
https://doaj.org/article/c399322da1954873b5a5009687d5c4f4
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7165 (2021)
Genetic splice variants have become of central interest in recent years, as they play an important role in different cancers. Little is known about splice variants in melanoma. Here, we analyzed a genome-wide transcriptomic dataset of benign melanocy
Externí odkaz:
https://doaj.org/article/33422fa946974cca8b69f9d8dd14a56e