Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Manfred Grabherr"'
Autor:
Jonas Kjellin, Maria Pränting, Frauke Bach, Roshan Vaid, Bart Edelbroek, Zhiru Li, Marc P. Hoeppner, Manfred Grabherr, Ralph R. Isberg, Monica Hagedorn, Fredrik Söderbom
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background During infection by intracellular pathogens, a highly complex interplay occurs between the infected cell trying to degrade the invader and the pathogen which actively manipulates the host cell to enable survival and proliferation.
Externí odkaz:
https://doaj.org/article/f8916d4c0cc247a18e96cca2e49dbd87
Publikováno v:
Sensors, Vol 22, Iss 13, p 4957 (2022)
The current gold standard of gait diagnostics is dependent on large, expensive motion-capture laboratories and highly trained clinical and technical staff. Wearable sensor systems combined with machine learning may help to improve the accessibility o
Externí odkaz:
https://doaj.org/article/8e96d103067740ad998cf903c1353f94
Autor:
Andreas N. Schneider, John Sundh, Görel Sundström, Kerstin Richau, Nicolas Delhomme, Manfred Grabherr, Vaughan Hurry, Nathaniel R. Street
Publikováno v:
mSystems, Vol 6, Iss 1 (2021)
ABSTRACT The health, growth, and fitness of boreal forest trees are impacted and improved by their associated microbiomes. Microbial gene expression and functional activity can be assayed with RNA sequencing (RNA-Seq) data from host samples. In contr
Externí odkaz:
https://doaj.org/article/1f0ed9d9056a4e8cb8f39137b1257016
Autor:
Susanne Bornelöv, Eyal Seroussi, Sara Yosefi, Sharon Benjamini, Shoval Miyara, Mark Ruzal, Manfred Grabherr, Nima Rafati, Anna-Maja Molin, Ken Pendavis, Shane C. Burgess, Leif Andersson, Miriam Friedman-Einat
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background The mammalian adipose tissue plays a central role in energy-balance control, whereas the avian visceral fat hardly expresses leptin, the key adipokine in mammals. Therefore, to assess the endocrine role of adipose tissue in birds,
Externí odkaz:
https://doaj.org/article/14a8a0176c224404a676c78358f41448
Autor:
Ahmed Elewa, Heng Wang, Carlos Talavera-López, Alberto Joven, Gonçalo Brito, Anoop Kumar, L. Shahul Hameed, May Penrad-Mobayed, Zeyu Yao, Neda Zamani, Yamen Abbas, Ilgar Abdullayev, Rickard Sandberg, Manfred Grabherr, Björn Andersson, András Simon
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The Iberian ribbed newt Pleurodeles waltl has a wide spectrum of regeneration abilities. Here, Elewa et al. sequence its ~20 Gb genome and transcriptome to investigate the molecular features underlying its regenerative capacities.
Externí odkaz:
https://doaj.org/article/8603ee4fc70f43cb954d6dbc700923f8
Autor:
Emma Åberg, Fulvio Saccoccia, Manfred Grabherr, Wai Ying Josefin Ore, Per Jemth, Greta Hultqvist
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background The p53 signalling pathway, which controls cell fate, has been extensively studied due to its prominent role in tumor development. The pathway includes the tumor supressor protein p53, its vertebrate paralogs p63 and p73, and thei
Externí odkaz:
https://doaj.org/article/1448df03effb495cbdead3e2e73f6bcc
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background DNA methylation is a major mechanism involved in the epigenetic state of a cell. It has been observed that the methylation status of certain CpG sites close to or within a gene can directly affect its expression, either by silenci
Externí odkaz:
https://doaj.org/article/e06afbe995394fb7af3e86989467eec0
Autor:
Susanne Bornelöv, Eyal Seroussi, Sara Yosefi, Ken Pendavis, Shane C. Burgess, Manfred Grabherr, Miriam Friedman-Einat, Leif Andersson
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-4 (2017)
Abstract Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequen
Externí odkaz:
https://doaj.org/article/f227b6b4b142481da13666ff1c2e1220
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Background A common challenge in bioinformatics is to identify short sub-sequences that are unique in a set of genomes or reference sequences, which can efficiently be achieved by k-mer (k consecutive nucleotides) counting. However, there ar
Externí odkaz:
https://doaj.org/article/5190c210442540a2b04886cec6d393ff
Autor:
Showgy Y Ma'ayeh, Jingyi Liu, Dimitra Peirasmaki, Katarina Hörnaeus, Sara Bergström Lind, Manfred Grabherr, Jonas Bergquist, Staffan G Svärd
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006120 (2017)
BACKGROUND:Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis in humans, the most common form of parasite-induced diarrhea. Disease mechanisms are not completely defined and very few virulence factors are known. METHODOL
Externí odkaz:
https://doaj.org/article/23d3933b256048798e1ca45a77863f6d