Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Manfred Gerlach"'
Autor:
Regina Taurines, Gesa Kunkel, Stefanie Fekete, Jörg M. Fegert, Christoph Wewetzer, Christoph U. Correll, Kristian Holtkamp, Isabel Böge, Tobias Johann Renner, Hartmut Imgart, Maike Scherf-Clavel, Peter Heuschmann, Manfred Gerlach, Marcel Romanos, Karin Egberts
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 772 (2024)
Introduction: Fluvoxamine is used in children and adolescents (‘youths’) for treating obsessive compulsive disorder (OCD) but also off-label for depressive and anxiety disorders. This study aimed to investigate the relationship between fluvoxamin
Externí odkaz:
https://doaj.org/article/9b217ca473d440a1a99333332d322ba6
Autor:
Diana Dubrall, Stefanie Fekete, Sarah Leitzen, Lena Marie Paschke, Marcel Romanos, Matthias Schmid, Manfred Gerlach, Bernhardt Sachs
Publikováno v:
BMC Pharmacology and Toxicology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Since the warnings by the United States (US) and European regulatory authorities in 2004 and 2005 it had been discussed whether there is some link between selective serotonin reuptake inhibitors (SSRIs) and suicidality in the pedi
Externí odkaz:
https://doaj.org/article/913618f4a01c4000aa869f8202533858
Autor:
Michael Frey, Lukasz Smigielski, Elvira Tini, Stefanie Fekete, Christian Fleischhaker, Christoph Wewetzer, Andreas Karwautz, Christoph U. Correll, Manfred Gerlach, Regina Taurines, Paul L. Plener, Uwe Malzahn, Selina Kornbichler, Laura Weninger, Matthias Brockhaus, Su-Yin Reuter-Dang, Karl Reitzle, Hans Rock, Hartmut Imgart, Peter Heuschmann, Stefan Unterecker, Wolfgang Briegel, Tobias Banaschewski, Jörg M. Fegert, Tobias Hellenschmidt, Michael Kaess, Michael Kölch, Tobias Renner, Christian Rexroth, Susanne Walitza, Gerd Schulte-Körne, Marcel Romanos, Karin Maria Egberts
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2202 (2023)
Fluoxetine is the recommended first-line antidepressant in many therapeutic guidelines for children and adolescents. However, little is known about the relationships between drug dose and serum level as well as the therapeutic serum reference range i
Externí odkaz:
https://doaj.org/article/204809af7ca7493e9484cd39644b9394
Autor:
Luzie Eichentopf, Christoph Hiemke, Andreas Conca, Jan Engelmann, Manfred Gerlach, Ursula Havemann-Reinecke, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Klaus Lieb, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Gerald Zernig, Gerhard Gründer, Xenia M. Hart
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram. Furthermore
Externí odkaz:
https://doaj.org/article/d11abfae948b48b08146a8a3d4e2d368
Autor:
Elvira Tini, Lukasz Smigielski, Marcel Romanos, Christoph Wewetzer, Andreas Karwautz, Karl Reitzle, Christoph U. Correll, Paul L. Plener, Uwe Malzahn, Peter Heuschmann, Stefan Unterecker, Maike Scherf-Clavel, Hans Rock, Gisela Antony, Wolfgang Briegel, Christian Fleischhaker, Tobias Banaschewski, Tobias Hellenschmidt, Hartmut Imgart, Michael Kaess, Michael Kölch, Tobias Renner, Su-Yin Reuter-Dang, Christian Rexroth, Gerd Schulte-Körne, Frank Theisen, Stefanie Fekete, Regina Taurines, Manfred Gerlach, Karin Maria Egberts, Susanne Walitza
Publikováno v:
Comprehensive Psychiatry, Vol 115, Iss , Pp 152301- (2022)
Background: Sertraline is a selective serotonin reuptake inhibitor with specific indications in child and adolescent psychiatry. Notwithstanding its frequent use and clinical benefits, the relationship between pharmacokinetics, pharmacodynamics, effi
Externí odkaz:
https://doaj.org/article/3f307d4ad67e41c2953892d0473505e5
Autor:
Hans-Christoph Aster, Marcel Romanos, Susanne Walitza, Manfred Gerlach, Andreas Mühlberger, Albert Rizzo, Marta Andreatta, Natalie Hasenauer, Philipp E. Hartrampf, Kai Nerlich, Christoph Reiners, Reinhard Lorenz, Andreas K. Buck, Lorenz Deserno
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Background:Methylphenidate (MPH) is the first-line pharmacological treatment of attention-deficit/hyperactivity disorder (ADHD). MPH binds to the dopamine (DA) transporter (DAT), which has high density in the striatum. Assessments of the striatal dop
Externí odkaz:
https://doaj.org/article/bc0aa0c0aeb944de92d9571e40a108a6
Autor:
Maximilian Wulf, Katalin Barkovits, Karin Schork, Martin Eisenacher, Peter Riederer, Manfred Gerlach, Britta Eggers, Katrin Marcus
Publikováno v:
Cells, Vol 11, Iss 22, p 3538 (2022)
Neuromelanin granules (NMGs) are organelle-like structures present in the human substantia nigra pars compacta. In addition to neuromelanin, NMGs contain proteins, lipids and metals. As NMG-containing dopaminergic neurons are preferentially lost in P
Externí odkaz:
https://doaj.org/article/e2a75738a27249ceba7ed7da1697d1bc
Autor:
Mareike Fauser, Grit Weselek, Christine Hauptmann, Franz Markert, Manfred Gerlach, Andreas Hermann, Alexander Storch
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
The major catecholamines—dopamine (DA) and norepinephrine (NE)—are not only involved in synaptic communication but also act as important trophic factors and might ultimately be involved in mammalian brain development. The catecholaminergic innerv
Externí odkaz:
https://doaj.org/article/b9c4155acbdd4d9a8e39a1009909c801
Publikováno v:
Data in Brief, Vol 23, Iss , Pp - (2019)
This article describes a mass spectrometric data set generated from human substantia nigra tissue that was spiked with iRT peptides. The data set can be used as a spectral library for analysis of the human brain; especially for analysis of human subs
Externí odkaz:
https://doaj.org/article/f6ffc35c792341c6ae7c0b0a880ba27f
Autor:
Sarah Plum, Britta Eggers, Stefan Helling, Markus Stepath, Carsten Theiss, Renata E. P. Leite, Mariana Molina, Lea T. Grinberg, Peter Riederer, Manfred Gerlach, Caroline May, Katrin Marcus
Publikováno v:
Cells, Vol 9, Iss 12, p 2580 (2020)
The pathological hallmark of Parkinson’s disease (PD) is the loss of neuromelanin-containing dopaminergic neurons within the substantia nigra pars compacta (SNpc). Additionally, numerous studies indicate an altered synaptic function during disease
Externí odkaz:
https://doaj.org/article/a6d14feb8d634539a742d87c98fb4de9