Výsledky vyhledávání - "Manfred Braun"

Akademický článek

Synthesis of the aglycon of scorzodihydrostilbenes B and D

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 610-616 (2019)

Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scor

Externí odkaz: https://doaj.org/article/9b196c8402f14f48af106ee79bdf51da

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Akademický článek

Synthesis of 5-oxyquinoline derivatives for reversal of multidrug resistance

Autor: Torsten Dittrich, Nils Hanekop, Nacera Infed, Lutz Schmitt, Manfred Braun

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1700-1704 (2012)

The inhibition of ABC (ATP binding cassette) transporters is considered a powerful tool to reverse multidrug resistance. Zosuquidar featuring a difluorocyclopropyl-annulated dibenzosuberyl moiety has been found to be an inhibitor of the P-glycoprotei

Externí odkaz: https://doaj.org/article/187fad9cbe8647008d19360a5927fe30

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Akademický článek

Stereogenic boron in 2-amino-1,1-diphenylethanol-based boronate–imine and amine complexes

Autor: Sebastian Schlecht, Walter Frank, Manfred Braun

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 615-621 (2011)

Racemic boronate–imine and boronate–amine complexes 8 and 10, both featuring a stereogenic boron atom were synthesized from 2-amino-1,1-diphenylethanol (5) and characterized by crystal structure analyses. Proof of enantiomerism at the boron cente

Externí odkaz: https://doaj.org/article/cffca597c50a48a3bb8146ccce1cd8ca

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Akademický článek

Novel Spiroannulated 3-Benzofuranones. Synthesis and Inhibition of the Human Peptidyl Prolyl cis/trans Isomerase Pin1

Autor: Gunter Fischer, Birte Hernandez Alvarez, Boris FÃƒÂ©aux de Lacroix, Anahita Hessamian-Alinejad, Manfred Braun

Publikováno v: Molecules, Vol 13, Iss 4, Pp 995-1003 (2008)

The novel 3H-spiro[1-benzofuran-2-cyclopentan]-3-one skeleton has been madeaccessible by different routes. One- and two-step protocols lead to tricyclic and tetracyclicbenzofuranones 2 and 3, respectively. A four-step synthesis to spirocompound 4 isd

Externí odkaz: https://doaj.org/article/7f7715edb47a4e8fbfba25cd1cc8d0fe

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Akademický článek

Synthesis of the fluorescent amino acid rac-(7-hydroxycoumarin-4-yl)ethylglycine

Autor: Manfred Braun, Torsten Dittrich

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, p 69 (2010)

The hydrochloride of the racemic amino acid (7-hydroxycoumarin-4-yl)ethylglycine, a versatile fluorescent probe in proteins, has been synthesized in five steps from commercially available (7-hydroxycoumarin-4-yl)acetic acid. The key step involves the

Externí odkaz: https://doaj.org/article/8fe708ef11d94f97b275f94ca5e42bc8

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