Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Manfred Alsheimer"'
Autor:
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The cellular membrane in male meiotic germ cells contains a unique class of phospholipids and sphingolipids that is required for male reproduction. Here, we show that a conserved membrane fluidity sensor, AdipoR2, regulates the meiosis-speci
Externí odkaz:
https://doaj.org/article/4db1054da05548adae43cd8b6f7c67cf
Autor:
Indrajit Nanda, Susanne Schories, Ivan Simeonov, Mateus Contar Adolfi, Kang Du, Claus Steinlein, Manfred Alsheimer, Thomas Haaf, Manfred Schartl
Publikováno v:
Cells, Vol 11, Iss 7, p 1118 (2022)
The conspicuous colour sexual dimorphism of guppies has made them paradigmatic study objects for sex-linked traits and sex chromosome evolution. Both the X- and Y-chromosomes of the common guppy (Poecilia reticulata) are genetically active and homomo
Externí odkaz:
https://doaj.org/article/0dd44434d69b410681508829dd80ba4a
Autor:
Marketa Koncicka, Jakub Cervenka, Daniel Jahn, Rita Sucha, Petr Vodicka, Ahmed Gad, Manfred Alsheimer, Andrej Susor
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0229781 (2020)
Lamin C2 (LMN C2) is a short product of the lamin a gene. It is a germ cell-specific lamin and has been extensively studied in male germ cells. In this study, we focussed on the expression and localization of LMN C2 in fully-grown germinal vesicle (G
Externí odkaz:
https://doaj.org/article/80674959640444489fa546b9a0fda065
Publikováno v:
Biology Open, Vol 4, Iss 12, Pp 1792-1802 (2015)
LINC complexes are evolutionarily conserved nuclear envelope bridges, physically connecting the nucleus to the peripheral cytoskeleton. They are pivotal for dynamic cellular and developmental processes, like nuclear migration, anchoring and positioni
Externí odkaz:
https://doaj.org/article/39b873fe1a2d44958dd9d360932b23d4
Autor:
Jana Link, Monika Leubner, Johannes Schmitt, Eva Göb, Ricardo Benavente, Kuan-Teh Jeang, Rener Xu, Manfred Alsheimer
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004099 (2014)
LINC complexes are evolutionarily conserved nuclear envelope bridges, composed of SUN (Sad-1/UNC-84) and KASH (Klarsicht/ANC-1/Syne/homology) domain proteins. They are crucial for nuclear positioning and nuclear shape determination, and also mediate
Externí odkaz:
https://doaj.org/article/03be2a28102e44d3a9ab7b1620ecc036
Autor:
Jana Link, Daniel Jahn, Johannes Schmitt, Eva Göb, Johannes Baar, Sagrario Ortega, Ricardo Benavente, Manfred Alsheimer
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003261 (2013)
The nuclear lamina is the structural scaffold of the nuclear envelope and is well known for its central role in nuclear organization and maintaining nuclear stability and shape. In the past, a number of severe human disorders have been identified to
Externí odkaz:
https://doaj.org/article/d13752f951f142cdb898c1201f37af75
Autor:
Sabine Schramm, Johanna Fraune, Ronald Naumann, Abrahan Hernandez-Hernandez, Christer Höög, Howard J Cooke, Manfred Alsheimer, Ricardo Benavente
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002088 (2011)
The synaptonemal complex (SC) is a proteinaceous, meiosis-specific structure that is highly conserved in evolution. During meiosis, the SC mediates synapsis of homologous chromosomes. It is essential for proper recombination and segregation of homolo
Externí odkaz:
https://doaj.org/article/6f8e81dbee0a476b97b30e31fead3c2d
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12072 (2010)
BACKGROUND: LINC complexes are nuclear envelope bridging protein structures formed by interaction of SUN and KASH proteins. They physically connect the nucleus with the peripheral cytoskeleton and are critically involved in a variety of dynamic proce
Externí odkaz:
https://doaj.org/article/83806974dcf74cd286c305861683e206
Publikováno v:
Journal of Cell Science. 136
SUN domain proteins are conserved proteins of the nuclear envelope and key components of the LINC complexes (for ‘linkers of the nucleoskeleton and the cytoskeleton’). Previous studies have demonstrated that the testis-specific SUN domain protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba7cff845ba1513f637bc8fb577ffa6
https://doi.org/10.1242/jcs.260155
https://doi.org/10.1242/jcs.260155
Autor:
Dmitrij Dedukh, Irene da Cruz, Susanne Kneitz, Anatolie Marta, Jenny Ormanns, Tomáš Tichopád, Yuan Lu, Manfred Alsheimer, Karel Janko, Manfred Schartl
Publikováno v:
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 30(4)
Unisexual reproduction, which generates clonal offspring, is an alternative strategy to sexual breeding and occurs even in vertebrates. A wide range of non-sexual reproductive modes have been described, and one of the least understood questions is ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5232c17db77e0b9b01eff58d074329
https://pubmed.ncbi.nlm.nih.gov/36459298
https://pubmed.ncbi.nlm.nih.gov/36459298