Výsledky vyhledávání - "Manfred, Schmolz"

Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study

Publikováno v: Clinical Immunology
Clinical Immunology, Elsevier, 2017, ⟨10.1016/j.clim.2017.09.019⟩
Clinical Immunology, 2017, ⟨10.1016/j.clim.2017.09.019⟩
Clinical Immunology, Elsevier, 2017, 〈10.1016/j.clim.2017.09.019〉
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Functional immune responses are increasingly important for clinical studies, providing in depth biomarker information to assess immunotherapy or vaccination. Incorporating functional immune assays into routine clinical practice has remained limited d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aebb57017b24ab9f5acc43e61dabc17
https://pubmed.ncbi.nlm.nih.gov/28943400

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Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood

Autor: Gerburg M. Stein, Michael Blum, Nadja Baur, Michael Schmohl, Thomas O. Joos, Kathrin Hefner, Manfred Schmolz, Nicole Schneiderhan-Marra

Publikováno v: International Immunopharmacology. 14:722-728

The human immune system represents a highly complex multicellular network that protects the organism against the environment and pathogens. Within this system, different immune cells communicate with each other, as well as with adjacent organs and ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311fcd1abde3c244248c844e35c65f36
https://doi.org/10.1016/j.intimp.2012.10.010

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Placebo-controlled Randomized Clinical Trial on the Immunomodulating Activities of Low- and High-Dose Bromelain after Oral Administration - New Evidence on the Antiinflammatory Mode of Action of Bromelain

Autor: Peter Meiser, Silke Müller, Klaus Eschmann, Manfred Schmolz, Reinhard März, Bernd Drewelow

Publikováno v: Phytotherapy Research. 27:199-204

Bromelain has been used for treatment of inflammatory diseases for decades. However, the exact mechanism of action remains poorly understood. While in vitro investigations have shown conflicting effects on the release of various cytokines, no in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b489155e983c954da00efcf093503b28
https://doi.org/10.1002/ptr.4678

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An Innovative, Centrifugation-free Method to Prepare Human Platelet Mediator Concentrates Showing Activities Comparable to Platelet-rich Plasma

Autor: Manfred, Schmolz, Gerburg M, Stein, Wolf-Dietrich, Hubner

Publikováno v: Wounds : a compendium of clinical research and practice. 23(6)

Slow-healing wounds benefit considerably from treatment with platelet-rich plasma (PrP). The drawback of using PrP is its laborious preparation, which requires expensive technical equipment (centrifuges) and well-trained personnel.The authors' new me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf871eb527035438b38d5a6df11390c5
https://pubmed.ncbi.nlm.nih.gov/25881364

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Immunomodulatory Activities of a Concentrated Fruit and Vegetable Juice Tested in a Randomized, Placebo-Controlled, Double-Blind Clinical Trial in Healthy Volunteers

Autor: Reinhard März, Manfred Schmolz, Carola Lauster, Marco Schaudt, Cornelia Schaudt

healthy volunteers were included in a randomized, placebo-controlled pilot study in order to investigate im- munomodulatory effects of a concentrated juice, containing the ingredients of a total of 80 different fruits, vege- tables, herbs, mushrooms,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9273026f80bf7643dc75962c8749b222
https://opus4.kobv.de/opus4-ohm/frontdoor/index/index/docId/8

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Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli

Publikováno v: Immunity
Immunity, 2014, 40 (3), pp.436-50. ⟨10.1016/j.immuni.2014.03.002⟩
Immunity, Elsevier, 2014, 40 (3), pp.436-50. ⟨10.1016/j.immuni.2014.03.002⟩
Immunity, Elsevier, 2014, 40 (3), pp.436-50. 〈10.1016/j.immuni.2014.03.002〉

International audience; Standardization of immunophenotyping procedures has become a high priority. We have developed a suite of whole-blood, syringe-based assay systems that can be used to reproducibly assess induced innate or adaptive immune respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9c32a1b940cf9c0d80beab85bfaab8
https://hal-pasteur.archives-ouvertes.fr/pasteur-01384537

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Functional drug candidate profiling using complex human organotypic cell culture models: a promising way to reduce clinical drug failure

Autor: Manfred Schmolz

Publikováno v: Expert opinion on drug discovery. 2(7)

The human immune system is one of the most important causative factors in the pathogenesis of various chronic inflammatory diseases. The network of immunoregulatory signals ruling the course of such disorders is highly complex and does not only invol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9242010849589158f068f8739c7c5b
https://pubmed.ncbi.nlm.nih.gov/23484814

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