Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Manel Zeghal"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Representing the most attractive and successful druggable receptors of the proteome, GPCRs regulate a myriad of physiological and pathophysiological functions. Although over half of present pharmaceuticals target GPCRs, the advancement of dr
Externí odkaz:
https://doaj.org/article/fec0d6604944450cb05f7a19f09c593c
Representing the most attractive and successful druggable receptors of the proteome, GPCRs regulate a myriad of physiological and pathophysiological functions. Although over half of present pharmaceuticals target GPCRs, the advancement of drug discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e139ca871c1f16cd794735ea574750
https://doi.org/10.21203/rs.3.rs-2772908/v1
https://doi.org/10.21203/rs.3.rs-2772908/v1
Autor:
Abdulhamid O. Mohamud, Manel Zeghal, Shivani Patel, Geneviève Laroche, Nuria Blgacim, Patrick M. Giguère
Publikováno v:
ACS Omega. 7:16939-16951
Existing pharmacotherapies acting on the opioid receptor system have been extensively used to treat chronic pain and addictive disorders. Nevertheless, the adverse side effects associated with opioid therapy underscore the need for concerted measures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98e3393ed08681defec929a4652a05d
https://doi.org/10.1021/acsomega.1c07226
https://doi.org/10.1021/acsomega.1c07226
Autor:
Manel Zeghal, Kevin Matte, Angelica Venes, Shivani Patel, Geneviève Laroche, Sabina Sarvan, Monika Joshi, Jean-François Couture, Patrick M. Giguère
/SUMMARYProtein-protein interactions (PPIs) form the underpinnings of any cellular signaling network. PPIs are highly dynamic processes and often, cell-based assays can be essential for their study as they closely mimic the biological intricacies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a5fa096e221a77de7142a759220e5ce
https://doi.org/10.1101/2023.02.05.527200
https://doi.org/10.1101/2023.02.05.527200
Publikováno v:
Journal of visualized experiments : JoVE. (157)
As the largest and most versatile gene superfamily and mediators of a gamut of cellular signaling pathways, G-protein-coupled receptors (GPCRs) represent one of the most promising targets for the pharmaceutical industry. Ergo, the design, implementat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::105e0b1c5f2370cb4a9216ed0c4f92f1
https://pubmed.ncbi.nlm.nih.gov/32225148
https://pubmed.ncbi.nlm.nih.gov/32225148
Publikováno v:
Journal of Visualized Experiments.
As the largest and most versatile gene superfamily and mediators of a gamut of cellular signaling pathways, G-protein-coupled receptors (GPCRs) represent one of the most promising targets for the pharmaceutical industry. Ergo, the design, implementat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523c99e6d40b29a87ec199c567f23c59
https://doi.org/10.3791/60823
https://doi.org/10.3791/60823
Publikováno v:
Vitamins and hormones. 111
The delta opioid receptor (DOP) belongs to the Class A, rhodopsin-like family of G protein-coupled receptors. Although this receptor has a high level of similarity with the other opioid receptors, it displays unique aspects and functions. Indeed, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11013c1df16cceb7f639e0c59ddbb934
https://pubmed.ncbi.nlm.nih.gov/31421707
https://pubmed.ncbi.nlm.nih.gov/31421707
The delta opioid receptor (DOP) belongs to the Class A, rhodopsin-like family of G protein-coupled receptors. Although this receptor has a high level of similarity with the other opioid receptors, it displays unique aspects and functions. Indeed, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9f6cacb3e5dc26b63857b9070460ba
https://doi.org/10.1016/bs.vh.2019.06.001
https://doi.org/10.1016/bs.vh.2019.06.001