Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Manel Dahmene"'
Autor:
Sébastien Thériault, Zhonglin Li, Erik Abner, Jian’an Luan, Hasanga D. Manikpurage, Ursula Houessou, Pardis Zamani, Mewen Briend, Estonian Biobank Research Team, Dominique K. Boudreau, Nathalie Gaudreault, Lily Frenette, Déborah Argaud, Manel Dahmene, François Dagenais, Marie-Annick Clavel, Philippe Pibarot, Benoit J. Arsenault, S. Matthijs Boekholdt, Nicholas J. Wareham, Tõnu Esko, Patrick Mathieu, Yohan Bossé
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract There is currently no medical therapy to prevent calcific aortic valve stenosis (CAVS). Multi-omics approaches could lead to the identification of novel molecular targets. Here, we perform a genome-wide association study (GWAS) meta-analysis
Externí odkaz:
https://doaj.org/article/5660b9921e9f456da6aee9115481bb7c
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS Biology, Vol 20, Iss 3, p e3001578 (2022)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Externí odkaz:
https://doaj.org/article/2345db5e865f4420afb480af79493bdb
Publikováno v:
Cancers, Vol 13, Iss 17, p 4362 (2021)
Skin cancers are the most common cancers worldwide. Among them, melanoma, basal cell carcinoma of the skin and cutaneous squamous cell carcinoma are the three major subtypes. These cancers are characterized by different genetic perturbations even tho
Externí odkaz:
https://doaj.org/article/7a814da3d4b642f88935b1fc73195ec7
Publikováno v:
Cells, Vol 9, Iss 6, p 1430 (2020)
Since their discovery, Rho GTPases have emerged as key regulators of cytoskeletal dynamics. In humans, there are 20 Rho GTPases and more than 150 regulators that belong to the RhoGEF, RhoGAP, and RhoGDI families. Throughout development, Rho GTPases c
Externí odkaz:
https://doaj.org/article/0e6fc7ce19b440078f45ea5f19cf5863
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M. Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A. Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS biology. 20(3)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4362, p 4362 (2021)
Cancers, Vol 13, Iss 4362, p 4362 (2021)
Simple Summary Skin cancer is the most common cancer in human. Melanoma, basal cell carcinoma and squamous cell carcinoma are the most prevalent skin cancer subtypes. A better understanding of the molecular mechanisms that contribute to the progressi
Autor:
Martin Lévesque, Edward A. Fon, Francesca Cicchetti, Thomas M. Durcan, Charleen Salesse, Sarah Malvaut, Omid Tavassoly, Marilyn Dubois, Walid Idi, Jérôme Lamontagne-Proulx, Raquel Rodriguez-Aller, Wen Luo, Abid Oueslati, Marie-Ève Tremblay, Maxime Teixeira, Morgan Bérard, Raza Qazi, Marie-Kim St-Pierre, Jae-Woong Jeong, Esther Del Cid-Pellitero, Razan Sheta, Denis Soulet, Roxanne Turmel, Manel Dahmene, Melanie Alpaugh, Luc Vallières, Armen Saghatelyan
Publikováno v:
SSRN Electronic Journal.
α-Synuclein (α-syn) aggregation into insoluble deposits, referred to as Lewy bodies (LBs), is the paramount pathological hallmark of Parkinson’s disease (PD) and related α-synucleinopathies. However, the mechanism by which these aggregates contr
Publikováno v:
Cells, Vol 9, Iss 1430, p 1430 (2020)
Cells
Cells
Since their discovery, Rho GTPases have emerged as key regulators of cytoskeletal dynamics. In humans, there are 20 Rho GTPases and more than 150 regulators that belong to the RhoGEF, RhoGAP, and RhoGDI families. Throughout development, Rho GTPases c
Autor:
Morgan Bérard, Charleen Salesse, Jérôme Lamontagne-Proulx, Jae-Woong Jeong, Manel Dahmene, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Omid Tavassoly, Marcos Schaan Profes, Sarah Malvaut, Abid Oueslati, Raza Qazi, Armen Saghatelyan, Edward A. Fon, Francesca Cicchetti, Martin Lévesque, Razan Sheta, Denis Soulet
Publikováno v:
SSRN Electronic Journal.
α-synuclein (α-syn) aggregation into insoluble deposits, referred to as Lewy bodies (LBs) is the paramount pathological hallmark of Parkinson’s disease and related α-synucleinopathies. However, how these aggregates affect neuronal homeostasis le