Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maneesh K. Yadav"'
Autor:
Maxim G Masiutin, Maneesh K Yadav
Publikováno v:
WikiJournal of Medicine. 10:X
Steroidogenic routes to androgens have been discovered and characterized over the last two decades that fall outside the Δ4 and Δ5 "classical androgen pathways" to testosterone and 5α-dihydrotestosterone. There has been considerable investigation
Autor:
Maxim G. Masiutin, Maneesh K. Yadav
Publikováno v:
Urology. 169:273
Autor:
Maneesh K. Yadav
Publikováno v:
New Journal of Chemistry. 41:1411-1416
This perspective outlines current capabilities and limitations of state-of-the-art artificial intelligence methods as applied to automating the planning of synthetic routes in organic chemistry. Synthetic organic chemistry is viewed from the perspect
Autor:
James H. McKerrow, Steven Chen, Danielle Kellar, Jair L. Siqueira-Neto, Michelle R. Arkin, Laura-Isobel McCall, Maneesh K. Yadav, E. Adam Kallel, Carolyn L. Talcott, Barry A. Bunin, Elizabeth L. Ponder, Sean Ekins, Malabika Sarker
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003878 (2015)
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003878 (2015)
Background Chagas disease is a neglected tropical disease (NTD) caused by the eukaryotic parasite Trypanosoma cruzi. The current clinical and preclinical pipeline for T. cruzi is extremely sparse and lacks drug target diversity. Methodology/Principal
Publikováno v:
Software, Services, and Systems ISBN: 9783319155449
Software, Services, and Systems
Software, Services, and Systems
We are interested in principles for designing and building open distributed systems consisting of multiple cyber-physical agents, specifically, where a coherent global view is unattainable and timely consensus is impossible. Such agents attempt to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa19b9fd4527cccb200d3cc1e96feb1
https://ir.cwi.nl/pub/23982
https://ir.cwi.nl/pub/23982
Autor:
Thomas P. Stratton, Xin Wang, Peter B. Madrid, Mike Travers, Joel S. Freundlich, Maneesh K. Yadav, Pauline Bourbon, Nisha Mittal, Matthew D. Zimmerman, Pradeep Kumar, Shao-Gang Li, Sean Ekins, Malabika Sarker, Carolyn L. Talcott
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141076 (2015)
PLoS ONE
PLoS ONE
Integrated computational approaches for Mycobacterium tuberculosis (Mtb) are useful to identify new molecules that could lead to future tuberculosis (TB) drugs. Our approach uses information derived from the TBCyc pathway and genome database, the Col
Autor:
Raymond C. Stevens, Maneesh K. Yadav, Valentina Tereshko, Peter Kuhn, Rustem F. Ismagilov, Irina Dementieva, Anthony A. Kossiakoff, Cory J. Gerdts, Frank R. Collart, Andrzej Joachimiak
Publikováno v:
Angewandte Chemie International Edition
This paper describes a method of time-controlled seeding to separate the stages of nucleation and growth in protein crystallization using a microfluidic device.
Autor:
Peter Kuhn, Raymond C. Stevens, Alexei Brooun, Vanitha Subramanian, Jeremiah S. Joseph, Jeffrey Velasquez, Mark T. Griffith, Kumar Singh Saikatendu, Kin Moy, Michael J. Buchmeier, Maneesh K. Yadav, Benjamin W. Neuman
Publikováno v:
Journal of Virology
The severe acute respiratory syndrome coronavirus (SARS-CoV) possesses a large 29.7-kb positive-stranded RNA genome. The first open reading frame encodes replicase polyproteins 1a and 1ab, which are cleaved to generate 16 “nonstructural” proteins
Autor:
Maneesh K. Yadav, C. David Stout, Charles L. Brooks, Luke J. Leman, Daniel J. Price, M. Reza Ghadiri
Publikováno v:
Biochemistry. 45:4463-4473
A detailed understanding of the mechanisms by which particular amino acid sequences can give rise to more than one folded structure, such as for proteins that undergo large conformational changes or misfolding, is a long-standing objective of protein
Publikováno v:
Proceedings of the National Academy of Sciences. 101:10872-10877
An ability to rationally design complex networks from the bottom up can offer valuable quantitative model systems for use in gaining a deeper appreciation for the principles governing the self-organization and functional characteristics of complex sy