Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Maneesh Gupta"'
Autor:
Julien Riposo, Maneesh Gupta
Publikováno v:
FinTech, Vol 3, Iss 1, Pp 116-134 (2024)
We introduce a model that derives a metric to answer the question: what is the expected gain of a staker? We calculate the rewards as the staking return in a Proof-of-Stake (PoS) consensus context. For each period of block validation and by a forward
Externí odkaz:
https://doaj.org/article/4b0eab3731394d7faa7296fc37cde0dd
Autor:
Claretta J. Sullivan, Kennedy Brown, Chia-Suei Hung, Joseph Kuo-Hsiang Tang, Mark DeSimone, Vincent Chen, Pamela F. Lloyd, Maneesh Gupta, Abby Juhl, Wendy Crookes-Goodson, Milana Vasudev, Patrick B. Dennis, Nancy Kelley-Loughnane
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nature offers many examples of materials which exhibit exceptional properties due to hierarchical assembly of their constituents. In well-studied multi-cellular systems, such as the morpho butterfly, a visible indication of having ordered su
Externí odkaz:
https://doaj.org/article/8e5a5d221c8846c291a5d21e6e83c903
Autor:
Erika B. Lindholm, Yi Z. Wang, Eugene A. Woltering, Leigh Ann Burns, Boudreaux Jp, Maneesh Gupta
Publikováno v:
The American Surgeon. 81:278-281
Recent increases in the use of over-the-counter (OTC) medicines and the underreporting of the use of these medications to physicians have sparked interest in the number and types of “supportive” therapies used by patients with neuroendocrine tumo
Publikováno v:
Alternative therapies in health and medicine. 22(4)
Context • Osteoarthritis (OA) is one of the most prevalent chronic diseases of the musculoskeleton, causing functional disability among older adults. Management of OA includes conventional pharmacological treatments consisting primarily of nonstero
Autor:
Andrey Finegersh, Maria T. Acosta, Maneesh Gupta, William H. Theodore, Jeeva Munasinghe, Phillip L. Pearl, K. Michael Gibson
Publikováno v:
Journal of Child Neurology. 25:1457-1461
Human succinic semialdehyde dehydrogenase deficiency, an autosomal recessive disorder of γ-aminobutyric acid (GABA) catabolism, was modeled by a murine model sharing the phenotype of ataxia and seizures. Magnetic resonance imaging (MRI) with volumet
Autor:
Glenn M. Eisen, Maneesh Gupta
Publikováno v:
Current Gastroenterology Reports. 11:345-353
NSAIDs incur significant gastrointestinal (GI) side effects. The complication risk increases with history of peptic ulcer or older age. Helicobacter pylori infection and cardioprotective aspirin have independent and additive risks in the presence of
Autor:
Ashok K. Mehta, Maneesh Gupta, Lawrence P. Carter, K. Michael Gibson, Maharaj K. Ticku, Georgianna G. Gould
Publikováno v:
Molecular Genetics and Metabolism. 88:86-89
We investigated whether succinate semialdehyde dehydrogenase deficiency alters γ-hydroxybutyric acid (GHB) receptor characteristics due to elevation of GHB levels in the mouse brain. The membrane homogenate binding and quantitative autoradiography u
Autor:
Markus Grompe, Henry Senephansiri, Cornelis Jakobs, Maneesh Gupta, Erwin E.W. Jansen, O. Carter Snead, K. Michael Gibson
Publikováno v:
Molecular Therapy. 9(4):527-539
Murine succinate semialdehyde dehydrogenase (SSADH) deficiency (OMIM 271980; EC 1.2.1.24), a model of the corresponding human disorder, displays 100% mortality at weeks 3-4 of life, associated with lethal tonic-clonic seizures. The biochemical hallma
Autor:
Phillip L. Pearl, Maneesh Gupta, Mendel Tuchman, O. Carter Snead, L. Gilbert Vezina, K. Michael Gibson, Cornelis Jakobs, L. M. E. Smit
Publikováno v:
Biological Psychiatry. 54:763-768
Background We report two adult patients with succinic semialdehyde dehydrogenase deficiency, manifesting as γ-hydroxybutyric aciduria. For both, the clinical presentation included significant behavioral disturbances and psychosis (hallucinations, di