Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy

Autor: Anna Lena Weber, Anne Kathrin Mayer, Bernhard Brenner, Carolyn Y. Ho, Theresia Kraft, Andreas Perrot, Judith Montag, Antonio Francino, Francesco Navarro-Lopez, Pia Ernstberger, Julia Rose, Britta Keyser, Jolanda van der Velden, Cristobal G. dos Remedios, Edgar Becker, Mandy Syring

Publikováno v: Journal of Muscle Research and Cell Motility
Journal of Muscle Research and Cell Motility, 1-12. Springer Netherlands
STARTPAGE=1;ENDPAGE=12;ISSN=0142-4319;TITLE=Journal of Muscle Research and Cell Motility
Montag, J, Syring, M, Rose, J, Weber, A L, Ernstberger, P, Mayer, A K, Becker, E, Keyser, B, Dos Remedios, C, Perrot, A, van der Velden, J, Francino, A, Navarro-Lopez, F, Ho, C Y, Brenner, B & Kraft, T 2017, ' Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy ', Journal of Muscle Research and Cell Motility, pp. 1-12 . https://doi.org/10.1007/s10974-017-9486-4

HCM, the most common inherited cardiac disease, is mainly caused by mutations in sarcomeric genes. More than a third of the patients are heterozygous for mutations in the MYH7 gene encoding for the β-myosin heavy chain. In HCM-patients, expression o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c92fd6165dbe39bab29a0be96f4ddd
https://doi.org/10.1007/s10974-017-9486-4