Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mandy Stubbendorff"'
Autor:
Tatjana P Harting, Mandy Stubbendorff, Susanne C Hammer, Patrik Schadzek, Anaclet Ngezahayo, Hugo Murua Escobar, Ingo Nolte
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178744 (2017)
Targeting mitochondrial energy metabolism is a novel approach in cancer research and can be traced back to the description of the Warburg effect. Dichloroacetate, a controversially discussed subject of many studies in cancer research, is a pyruvate d
Externí odkaz:
https://doaj.org/article/d2758f3f002e47aeb53103d9643afc90
Autor:
Tobias Deuse, Mandy Stubbendorff, Karis Tang-Quan, Neil Phillips, Mark A. Kay, Thomas Eiermann, Thang T. Phan, Hans-Dieter Volk, Hermann Reichenspurner, Robert C. Robbins, Sonja Schrepfer M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 20 (2011)
We here present an immunologic head-to-head comparison between human umbilical cord lining mesenchymal stem cells (clMSCs) and adult bone marrow MSCs (bmMSCs) from patients >65 years of age. clMSCs had significantly lower HLA class I expression, high
Externí odkaz:
https://doaj.org/article/287f0b6740294c8292602f8dac6c2e9e
Autor:
Siegfried Wagner, Patrik Schadzek, Saskia Willenbrock, Hugo Murua Escobar, Tatjana P. Harting, Anaclet Ngezahayo, Ingo Nolte, Mandy Stubbendorff
Publikováno v:
International Journal of Oncology. 49:2341-2350
The Warburg effect describes the ability of cancer cells to produce energy via aerobic glycolysis instead of oxidative phosphorylation of pyruvate. This deviation in mitochondrial metabolism inhibits apoptosis, allowing increased proliferation under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c68103b06970a24665fb20ee416cc3a
https://doi.org/10.3892/ijo.2016.3720
https://doi.org/10.3892/ijo.2016.3720
Autor:
Yan Chen, Joshua M. Spin, Thomas Renné, James B Fink, Tobias Deuse, Evgenios Neofytou, Sonja Schrepfer, Gary Park, Vanessa Taylor, Robert C. Robbins, Hermann Reichenspurner, Rainer Kiefmann, Mandy Stubbendorff, Xiaoqin Hua, Martina Kiefmann
Publikováno v:
Transplantation. 100:1022-1031
Background The efficacy of selective Janus kinase 1/3 inhibitor R507 to prevent obliterative airway disease was analyzed in preclinical airway transplantation models. Methods Orthotopic trachea transplantations were performed between Lewis donors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632195d4328ba11ee79192f622ea66a
https://doi.org/10.1097/tp.0000000000001110
https://doi.org/10.1097/tp.0000000000001110
Autor:
Antje Grabosch, Ryo Itagaki, Irving L. Weissman, Malik Alawi, Joachim Velden, Dong Wang, Robert C. Robbins, Xiaoqin Hua, Mandy Stubbendorff, Rudolf Jaenisch, Tobias Deuse, Sonja Schrepfer, Hermann Reichenspurner, X. Hu, Anne Grünewald, Laura C. Greaves
Publikováno v:
Cell Stem Cell. 16(1):33-38
Summary The generation of pluripotent stem cells by somatic cell nuclear transfer (SCNT) has recently been achieved in human cells and sparked new interest in this technology. The authors reporting this methodical breakthrough speculated that SCNT wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95146e0b7775b7fe1e447a3d532b9bd
Autor:
Karen Bieback, Mandy Stubbendorff, Hans-Dieter Volk, Xiaoqin Hua, Tobias Deuse, Sonja Schrepfer, Thomas Eiermann, Kerry Atkinson, Hermann Reichenspurner, Joachim Velden, Thang T. Phan, Robert C. Robbins, Christine Schröder
Publikováno v:
Stem Cells and Development. 22:2619-2629
Mesenchymal stromal cells (MSCs) have been isolated from many tissues, including gestational tissue. To date, a study comparing the properties and suitability of these cells in cell-based therapies is lacking. In this study, we compared the phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd9c84b5f4ba7b7d8a1779c542ba866
https://doi.org/10.1089/scd.2013.0043
https://doi.org/10.1089/scd.2013.0043
Autor:
Jaime Arroyo, Sumy Büchner, Mandy Stubbendorff, Martin Andreas, Antje Grabosch, Fredrik H. Halvorsen, Sabrina Siregard, Jan M. De Raet
Publikováno v:
Interactive CardioVascular and Thoracic Surgery. 16:772-776
OBJECTIVES: Gaining cardiac surgical competence is a complex, multifactorial process that may take years of experience and onthe-job training. It is critical to provide suitable educational opportunities to gain the necessary knowledge, judgment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e174c5f0ce5135fc963a2f36a6b2bd
https://doi.org/10.1093/icvts/ivt075
https://doi.org/10.1093/icvts/ivt075
Autor:
Sebastian Ullrich, Ryo Itagaki, Robert C. Robbins, Julien Guihaire, Hermann Reichenspurner, Mandy Stubbendorff, Peter Dorfmüller, Xiaoqin Hua, Udo Schumacher, Elie Fadel, Tobias Deuse, Sonja Schrepfer
Publikováno v:
Transplant international : official journal of the European Society for Organ Transplantation. 29(12)
Bronchiolitis obliterans syndrome (BOS) is a main cause of allograft dysfunction and mortality after lung transplantation (LTx). A better understanding of BOS pathogenesis is needed to overcome this treatment-refractory complication. Orthotopic trach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3122f64cd22ea14c34ae85a9eb7d4645
https://pubmed.ncbi.nlm.nih.gov/27614085
https://pubmed.ncbi.nlm.nih.gov/27614085
Autor:
Joachim Velden, Muhammad Baluom, Robert C. Robbins, Yan Chen, Mandy Stubbendorff, Vanessa Taylor, Thomas Streichert, Xiaoqin Hua, Hermann Reichenspurner, Tobias Deuse, Sonja Schrepfer, Gary Park
Publikováno v:
Transplantation. 94:695-702
Selective inhibition of lymphocyte activation through abrogation of signal 3-cytokine transduction emerges as a new strategy for immunosuppression. This is the first report on the novel Janus kinase (JAK)1/3 inhibitors R507 and R545 for prevention of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d52077a24e6a9fb931530a664c86c3
https://doi.org/10.1097/tp.0b013e3182660496
https://doi.org/10.1097/tp.0b013e3182660496
Autor:
Thomas Eschenhagen, Sonja Schrepfer, Mandy Stubbendorff, Lucie Carrier, Xiaoqin Hua, Jana Christina Müller, Dennis Mehrkens, Felix W. Friedrich, Florian Weinberger, Sylvia M. Evans
Publikováno v:
Circulation Research. 110:1303-1310
Rationale: The transcription factor Islet-1 is a marker of cardiovascular progenitors during embryogenesis. The isolation of Islet-1–positive (Islet-1 + ) cells from early postnatal hearts suggested that Islet-1 also marks cardiac progenitors in ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13fb1fb5a11c2e59df548eb9631852f
https://doi.org/10.1161/circresaha.111.259630
https://doi.org/10.1161/circresaha.111.259630