Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mandy Pierau"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Blockade of surface co-inhibitory receptor programmed cell death-1 (PD-1; CD279) has been established as an important immunotherapeutic approach to treat malignancies. On a cellular level, PD-1 is demonstrated to be of particular importance in inhibi
Externí odkaz:
https://doaj.org/article/0bd19b48b6bc45e1961ea1f2adf2f1c1
Assessment of Immune Status Using Inexpensive Cytokines: A Literature Review and Learning Approaches
Autor:
Noor Jamaludeen, Juliane Lehmann, Christian Beyer, Katrin Vogel, Mandy Pierau, Monika Brunner-Weinzierl, Myra Spiliopoulou
Publikováno v:
Sensors, Vol 22, Iss 24, p 9785 (2022)
The emergence of point-of-care (POC) testing has lately been promoted to deliver rapid, reliable medical tests in critical life-threatening situations, especially in resource-limited settings. Recently, POC tests have witnessed further advances due t
Externí odkaz:
https://doaj.org/article/36f5791b9220486db0773a647a4661bf
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Atopic diseases in childhood are a major burden worldwide and there is still a lack of knowledge about treatable causes. In industrialized countries such as Germany, almost every second child is sensitized to at least one common allergen. Recent stud
Externí odkaz:
https://doaj.org/article/f96f732c89914cb9ba63aba6b390d640
Autor:
Aditya Arra, Maximilian Pech, Hang Fu, Holger Lingel, Franziska Braun, Christian Beyer, Myra Spiliopoulou, Barbara M. Bröker, Karen Lampe, Christoph Arens, Katrin Vogel, Mandy Pierau, Monika C. Brunner-Weinzierl
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The monoclonal antibody against CTLA-4, Ipilimumab, is a first-in-class immune-checkpoint inhibitor approved for treatment of advanced melanoma in adults but not extensively studied in children. In light of the fact that the immune response early in
Externí odkaz:
https://doaj.org/article/184fafbd6a134358b3cb40addcf9ccf2
Autor:
Julienne Knolle, Mandy Pierau, Katrin Hebel, Karen Lampe, Gerhard Jorch, Siegfried Kropf, Christoph Arens, Monika C. Brunner-Weinzierl
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Every sixth child suffers from hypertrophy of the adenoid, a secondary lymphoid organ, at least once in childhood. Little is known about the impact of pathogen-provocation vs. developmental impact on T-cell responses after 1 year of age. Therefore, d
Externí odkaz:
https://doaj.org/article/2a43302ad11945258995057febac2af4
Autor:
Satish Ranjan, Alexander Goihl, Shrey Kohli, Ihsan Gadi, Mandy Pierau, Khurrum Shahzad, Dheerendra Gupta, Fabian Bock, Hongjie Wang, Haroon Shaikh, Thilo Kähne, Dirk Reinhold, Ute Bank, Ana C. Zenclussen, Jana Niemz, Tina M. Schnöder, Monika Brunner-Weinzierl, Thomas Fischer, Thomas Kalinski, Burkhart Schraven, Thomas Luft, Jochen Huehn, Michael Naumann, Florian H. Heidel, Berend Isermann
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Graft-vs.-host disease is a complication of allogenic hematopoietic stem cell transplantation, and is associated with endothelial dysfunction. Here the authors show that activated protein C signals via PAR2/PAR3 to expand Treg cells, mitigating the d
Externí odkaz:
https://doaj.org/article/17c58ccb118041e9a3a369a75450a669
Autor:
Aditya Arra, Holger Lingel, Benno Kuropka, Jonas Pick, Tina Schnoeder, Thomas Fischer, Christian Freund, Mandy Pierau, Monika C. Brunner-Weinzierl
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
As the blockade of inhibitory surface-molecules such as CTLA-4 on T cells has led to recent advances in antitumor immune therapy, there is great interest in identifying novel mechanisms of action of CD8+ T cells to evoke effective cytotoxic antitumor
Externí odkaz:
https://doaj.org/article/d44711ac464147418f16f40eff37397b
Publikováno v:
Allergy. 75:684-687
Autor:
Franziska Braun, Myra Spiliopoulou, Katrin Vogel, Karen Lampe, Christian Beyer, Hang Fu, Monika C. Brunner-Weinzierl, Barbara M. Bröker, Maximilian Pech, Holger Lingel, Mandy Pierau, Aditya Arra, Christoph Arens
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
The monoclonal antibody against CTLA-4, Ipilimumab, is a first-in-class immune-checkpoint inhibitor approved for treatment of advanced melanoma in adults but not extensively studied in children. In light of the fact that the immune response early in
Autor:
Dheerendra Gupta, Tina M. Schnöder, Thilo Kähne, Satish Ranjan, Thomas Luft, Jana Niemz, Dirk Reinhold, Shrey Kohli, Haroon Shaikh, Jochen Huehn, Berend Isermann, Hongjie Wang, Alexander Goihl, Florian H. Heidel, Burkhart Schraven, Ihsan Gadi, Thomas Kalinski, Ute Bank, Fabian Bock, Mandy Pierau, Khurrum Shahzad, Michael Naumann, Ana Claudia Zenclussen, Thomas Fischer, Monika C. Brunner-Weinzierl
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Nature Communications, 8:311
Nature Communications
Nature Communications, 8:311
Graft-vs.-host disease (GvHD) is a major complication of allogenic hematopoietic stem-cell(HSC) transplantation. GvHD is associated with loss of endothelial thrombomodulin, but the relevance of this for the adaptive immune response to transplanted HS