Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mandy Pack"'
Autor:
Selina Wrublewsky, Julia Glas, Christopher Carlein, Lisa Nalbach, Markus Daniel Alexander Hoffmann, Mandy Pack, Eloisa Aparecida Vilas-Boas, Nathan Ribot, Reinhard Kappl, Michael D. Menger, Matthias W. Laschke, Emmanuel Ampofo, Leticia Prates Roma
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102419- (2022)
Islet transplantation is a promising treatment strategy for type 1 diabetes mellitus (T1DM) patients. However, oxidative stress-induced graft failure due to an insufficient revascularization is a major problem of this therapeutic approach. NADPH oxid
Externí odkaz:
https://doaj.org/article/8c80ec14e87445ed9fb8f66cbec72608
Autor:
Lisa Nalbach, Leticia P Roma, Beate M Schmitt, Vivien Becker, Christina Körbel, Selina Wrublewsky, Mandy Pack, Thomas Später, Wolfgang Metzger, Maximilian M Menger, Florian S Frueh, Claudia Götz, Haopeng Lin, Jocelyn E Manning Fox, Patrick E MacDonald, Michael D Menger, Matthias W Laschke, Emmanuel Ampofo
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 1, Pp 1-21 (2020)
Abstract Pancreatic islet transplantation still represents a promising therapeutic strategy for curative treatment of type 1 diabetes mellitus. However, a limited number of organ donors and insufficient vascularization with islet engraftment failure
Externí odkaz:
https://doaj.org/article/74593c79fb6945478765ddc3d877bb8b
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 19 (2021)
The pyrazolopyrimidine based compound SGC-CK2-1 is a potent and highly specific CK2 inhibitor and a new tool to study the biological functions of protein kinase CK2 irrespective from off-target effects. We used this compound in comparison with the we
Externí odkaz:
https://doaj.org/article/f3189ab6bb8a442dafc113754671355e
Publikováno v:
Pharmaceutics, Vol 14, Iss 19, p 19 (2022)
Pharmaceutics; Volume 14; Issue 1; Pages: 19
Pharmaceutics
Pharmaceutics; Volume 14; Issue 1; Pages: 19
Pharmaceutics
The pyrazolopyrimidine based compound SGC-CK2-1 is a potent and highly specific CK2 inhibitor and a new tool to study the biological functions of protein kinase CK2 irrespective from off-target effects. We used this compound in comparison with the we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac3207e3bf8e7d9327ae6a1e34993ae
https://www.mdpi.com/1999-4923/14/1/19
https://www.mdpi.com/1999-4923/14/1/19
Autor:
Mandy Pack, Tim Nikolai Gulde, Michelle Victoria Völcker, Anne S. Boewe, Selina Wrublewsky, Emmanuel Ampofo, Mathias Montenarh, Claudia Götz
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 428
Glucose homeostasis is of critical importance for the survival of organisms. It is under hormonal control and often coordinated by the action of kinases and phosphatases. We have previously shown that CK2 regulates insulin production and secretion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0049d828a53395db9d1ab04811b8c7
https://pubmed.ncbi.nlm.nih.gov/36613872
https://pubmed.ncbi.nlm.nih.gov/36613872
Autor:
Selina Wrublewsky, Thimoteus Speer, Lisa Nalbach, Anne S. Boewe, Mandy Pack, Dalia Alansary, Leticia P. Roma, Markus D.A. Hoffmann, Beate M. Schmitt, Andrea Weinzierl, Michael D. Menger, Matthias W. Laschke, Emmanuel Ampofo
Publikováno v:
Diabetes. 71(8)
Hypoxia-induced islet cell death, caused by an insufficient revascularization of the grafts, is a major obstacle for successful pancreatic islet transplantation. Recently, it has been reported that the nucleotide-binding oligomerization domain (NOD)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b596fc6b54a409b4ebc18ea6d8ea27
https://pubmed.ncbi.nlm.nih.gov/35622000
https://pubmed.ncbi.nlm.nih.gov/35622000
Autor:
Thomas Später, Selina Wrublewsky, Emmanuel Ampofo, Vivien Becker, Leticia Prates Roma, Wolfgang Metzger, Haopeng Lin, Lisa Nalbach, Claudia Götz, Patrick E. MacDonald, Beate M Schmitt, Christina Körbel, Maximilian M Menger, Joseline E Manning Fox, Mandy Pack, Michael D. Menger, Matthias W. Laschke, Florian S. Frueh
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)
Pancreatic islet transplantation still represents a promising therapeutic strategy for curative treatment of type 1 diabetes mellitus. However, a limited number of organ donors and insufficient vascularization with islet engraftment failure restrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7096f9b064612283bc02b310ee193786
http://europepmc.org/articles/PMC7799357
http://europepmc.org/articles/PMC7799357