Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mandy Muller"'
Publikováno v:
Viruses, Vol 16, Iss 3, p 474 (2024)
A defining feature of a productive viral infection is the co-opting of host cell resources for viral replication. Despite the host repertoire of molecular functions and biological counter measures, viruses still subvert host defenses to take control
Externí odkaz:
https://doaj.org/article/06de95ad74764fe7996c7e39b4542196
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105887- (2023)
Summary: Extensive remodeling of host gene expression by nonstructural protein 1 (nsp1) of coronaviruses is a well-documented and conserved aspect of coronavirus-host takeover. Using comparative transcriptomics we investigated the diversity of transc
Externí odkaz:
https://doaj.org/article/763de4f4c4894f4ca177f9f81b2dd67f
Autor:
William Rodriguez, Mandy Muller
Publikováno v:
Viruses, Vol 14, Iss 6, p 1338 (2022)
Since its initial characterization in 2016, the interferon stimulated gene Shiftless (SHFL) has proven to be a critical piece of the innate immune response to viral infection. SHFL expression stringently restricts the replication of multiple DNA, RNA
Externí odkaz:
https://doaj.org/article/04cc7fb13cfb43018e6fef420c781389
Publikováno v:
Viruses, Vol 12, Iss 9, p 1024 (2020)
Kaposi’s sarcoma-associated herpesvirus (KSHV) induces life-long infections and has evolved many ways to exert extensive control over its host’s transcriptional and post-transcriptional machinery to gain better access to resources and dampened im
Externí odkaz:
https://doaj.org/article/78fd650a4d9a4d95a2ed81d2e780698f
Autor:
Mandy Muller, Britt A Glaunsinger
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006593 (2017)
During lytic Kaposi's sarcoma-associated herpesvirus (KSHV) infection, the viral endonu- clease SOX promotes widespread degradation of cytoplasmic messenger RNA (mRNA). However, select mRNAs, including the transcript encoding interleukin-6 (IL-6), es
Externí odkaz:
https://doaj.org/article/72b9eefc7ea848d2b842945000d019df
Autor:
Mandy Muller, Stephanie Hutin, Oliver Marigold, Kathy H Li, Al Burlingame, Britt A Glaunsinger
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004899 (2015)
During lytic Kaposi's sarcoma-associated herpesvirus (KSHV) infection, the viral endonuclease SOX promotes widespread degradation of cytoplasmic messenger RNA (mRNA). However, select mRNAs escape SOX-induced cleavage and remain robustly expressed. Pr
Externí odkaz:
https://doaj.org/article/b09a4bf619c2405e8f50833eafed67cf
Autor:
Mandy Muller, Caroline Demeret
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92581 (2014)
The Human Papillomavirus E2 proteins are key regulators of the viral life cycle, whose functions are commonly mediated through protein-protein interactions with the host cell proteome. We identified an interaction between E2 and a cellular protein ca
Externí odkaz:
https://doaj.org/article/3cfc4eafd3f04c15a133e87244e256d3
Autor:
Mandy Muller, Yves Jacob, Louis Jones, Amélie Weiss, Laurent Brino, Thibault Chantier, Vincent Lotteau, Michel Favre, Caroline Demeret
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002761 (2012)
Human Papillomaviruses (HPV) cause widespread infections in humans, resulting in latent infections or diseases ranging from benign hyperplasia to cancers. HPV-induced pathologies result from complex interplays between viral proteins and the host prot
Externí odkaz:
https://doaj.org/article/2be03d4cf36047a48fa4334873d83c72
Autor:
Mandy Muller
Publikováno v:
Seminars in Cell & Developmental Biology. 146:1
Publikováno v:
J Virol
Herpesviral infection reflects thousands of years of coevolution and the constant struggle between virus and host for control of cellular gene expression. During Kaposi’s sarcoma-associated herpesvirus (KSHV) lytic replication, the virus rapidly se