Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mandy Loo"'
Autor:
Fernando Rodríguez Pérez, Dean Natwick, Lauren Schiff, David McSwiggen, Alec Heckert, Melina Huey, Huntly Morrison, Mandy Loo, Rafael G. Miranda, John Filbin, Jose Ortega, Kayla Van Buren, Danny Murnock, Arnold Tao, Renee Butler, Kylie Cheng, William Tarvestad, Zhengjian Zhang, Eric Gonzalez, Rand M. Miller, Marcus Kelly, Yangzhong Tang, Jaclyn Ho, Daniel Anderson, Charlene Bashore, Stephen Basham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Synthetic lethality provides an attractive strategy for developing targeted cancer therapies. For example, cancer cells with high levels of microsatellite instability (MSI-H) are dependent on the Werner (WRN) helicase for survival. However,
Externí odkaz:
https://doaj.org/article/ce2bc19584424ac1a3b0cff592d3ad30
Publikováno v:
Tetrahedron Letters. 56:3497-3499
Herein is described an application of the acyl nitroso type 2 intramolecular Diels–Alder reaction as a key step in the progress toward the total synthesis of the Stemona alkaloid (−)-stenine. The chiral cycloaddition precursor is rapidly assemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535315ea77e241da1a651560afb49f67
https://doi.org/10.1016/j.tetlet.2015.03.043
https://doi.org/10.1016/j.tetlet.2015.03.043
Publikováno v:
The Journal of Organic Chemistry. 72:9402-9405
The type 2 intramolecular Diels-Alder (IMDA) reaction is a valuable method for synthesis of both carbocyclic and heterocyclic bridged bicyclo[5.3.1]undecane and bicyclo[4.3.1]decane ring systems. These structures are common to a number of biologicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0060fef1b6d3eb6ead33df14e6a11928
https://doi.org/10.1021/jo701964b
https://doi.org/10.1021/jo701964b
Publikováno v:
ChemInform. 39
The marine natural product dysibetaine was synthesized in racemic form from a levulinic acid derivative using a convertible isocyanide and an ammonium acetate in the Ugi 4-center-3-component condensation reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a588883f25e84acc4d832331d13851b5
https://doi.org/10.1002/chin.200835177
https://doi.org/10.1002/chin.200835177
Publikováno v:
ChemInform. 39
The type 2 intramolecular Diels-Alder (IMDA) reaction is a valuable method for synthesis of both carbocyclic and heterocyclic bridged bicyclo[5.3.1]undecane and bicyclo[4.3.1]decane ring systems. These structures are common to a number of biologicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::224e6b0b9c5bd1a2f5a3bee5132eceb1
https://doi.org/10.1002/chin.200813061
https://doi.org/10.1002/chin.200813061
Publikováno v:
Organic letters. 10(7)
The marine natural product dysibetaine was synthesized in racemic form from a levulinic acid derivative using a convertible isocyanide and an ammonium acetate in the Ugi 4-center-3-component condensation reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf0943528d516bb273aa5104e5f1b8e
https://pubmed.ncbi.nlm.nih.gov/18318540
https://pubmed.ncbi.nlm.nih.gov/18318540
Publikováno v:
Organic letters. 9(12)
A type 2 N-acylnitroso intramolecular Diels−Alder reaction followed by reductive N−O bond cleavage formed the B and C rings of the Stemona alkaloid stenine. Further elaboration provided the functionalized tricyclic core.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d08499cea1c5f2f2ced6153277af7b
https://pubmed.ncbi.nlm.nih.gov/17489596
https://pubmed.ncbi.nlm.nih.gov/17489596
Publikováno v:
Organic Letters; Apr2008, Vol. 10 Issue 7, p1461-1463, 3p
Publikováno v:
Organic Letters; Jun2007, Vol. 9 Issue 12, p2269-2271, 3p