Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mandy L. Y. Sin"'
Autor:
Helio A. Costa, William Shi, Chih Long Liu, Mohammad Shahrokh Esfahani, Dharati Trivedi, Henning Stehr, Harumi Lim, Maximilian Diehn, Aadel A. Chaudhuri, Simon B. Chen, Barzin Y. Nabet, Jonathan C. Dudley, Joseph G Schroers-Martin, Jacob J. Chabon, Ash A. Alizadeh, Daniel Lazzareschi, Mandy L. Y. Sin, Joseph C. Liao
Publikováno v:
Cancer Discovery. 9:500-509
Current regimens for the detection and surveillance of bladder cancer are invasive and have suboptimal sensitivity. Here, we present a novel high-throughput sequencing (HTS) method for detection of urine tumor DNA (utDNA) called utDNA CAPP-Seq (uCAPP
Autor:
Karen C. Carroll, Rajiv L. Gaur, VC Chu, Robert Kwiatkowski, Carlo Frederico Perno, Susan M. Butler-Wu, Mandy L. Y. Sin, Simranjit Singh, Ashley McEwan, Alice Nava, Jennifer L. Rakeman, Duy Nguyen, Randal C. Fowler, David H. Persing, Shobha Swaminathan, Na Zhang, David Alland, Jean-Michel Pawlotsky, Jo Ann Kop, Sukalyani Banik, Emma Davies, Michael J. Loeffelholz, Slim Fourati, Utsav Pandey, Heba H. Mostafa, Soumitesh Chakravorty, Padmapriya P. Banada
Publikováno v:
Journal of Clinical Microbiology
Nucleic acid amplification tests (NAATs) are the primary means of identifying acute infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Accurate and fast test results may permit more efficient use of protective and isol
Autor:
Mandy L. Y. Sin, Qian Zhao, Joseph C. Liao, Dharati Trivedi, Kathleen E. Mach, Nicolas Teslovich, Eugene Shkolyar, Ying Lu
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Risk stratification is critical in patients with non-muscle invasive bladder cancer. Urinary biomarkers have shown promise for bladder cancer detection however their clin...
Autor:
Fan Wu, Kathleen E. Mach, Dharati Trivedi, Emanuela Altobelli, Rahul Sinha, Debashis Sahoo, Kristin C. Jensen, Ying Lu, Joseph C. Liao, Mandy L. Y. Sin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 23, iss 14
Purpose: The majority of bladder cancer patients present with localized disease and are managed by transurethral resection. However, the high rate of recurrence necessitates lifetime cystoscopic surveillance. Developing a sensitive and specific urine
Publikováno v:
The Analyst. 141:652-660
Early detection of initial onset, as well as recurrence, of cancer is paramount for improved patient prognosis and human health. Cancer screening is enhanced by rapid differentiation of cancerous from non-cancerous cells which employs the inherent di
Autor:
Joseph C. Liao, Tingting Liu, Yi Lu, Vincent Gau, Mandy L. Y. Sin, Ariana C. Lamanda, Pak Kin Wong
Publikováno v:
SLAS Technology. 20:611-620
Alternating current (AC) electrokinetics is a collection of processes for manipulating bulk fluid mass and embedded objects with AC electric fields. The ability of AC electrokinetics to implement the major microfluidic operations, such as pumping, mi
Autor:
Maxwell V. Meng, G. Kenneth Jansz, Joseph C. Liao, Joseph Zadra, Wade J. Sexton, Russell Higuchi, Leena McCann, R. Blair Egerdie, Malini Satya, Jun Zhang, Shoichiro Ohta, Kathleen E. Mach, Julia A. Bridge, Michael Woods, Andrew M. Hiar, Ellen Wallace, Mandy L. Y. Sin, Huilin Wei, Douglas S. Scherr, Bernard Goldfarb, Yair Lotan, Edith Wong, Alon Z. Weizer
Publikováno v:
The Journal of urology. 199(3)
Despite suboptimal sensitivity urine cytology is often performed as an adjunct to cystoscopy for bladder cancer diagnosis. We aimed to develop a noninvasive, fast molecular diagnostic test for bladder cancer detection with better sensitivity than uri
Publikováno v:
Expert Review of Molecular Diagnostics
Rapid diagnosis of infectious diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Conventional in vitro diagnostics for infectious diseases are time-consu
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 10:159-166
Rapid detection of bacterial pathogens is critical toward judicious management of infectious diseases. Herein, we demonstrate an in situ electrokinetic stringency control approach for a self-assembled monolayer-based electrochemical biosensor toward
Publikováno v:
IEEE Nanotechnology Magazine. 7:31-37
Transforming microfluidics-based biosensing systems from laboratory research into clinical reality remains an elusive goal despite decades of intensive research. A fundamental obstacle in the development of fully automated microfluidic diagnostic sys