Výsledky vyhledávání - "Mandy L. Crowther"

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

Autor: Gail L. Wrigley, Shaun M. Fillery, Barry M. Hayter, Paula Perkins, Jason Grant Kettle, Emma J. Williams, Peter Mark Smith, Mandy L. Crowther, Rebecca J. Burton, Peter Robins, Neal J. Fazakerley, Caroline Anne McMillan

Publikováno v: Tetrahedron Letters. 54:6900-6904

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f60a61ec4c2e6a3963dffd65b51aad7e
https://doi.org/10.1016/j.tetlet.2013.10.035

Zobrazit plný text záznamu

Potent Cyclic Monomeric and Dimeric Peptide Inhibitors of VLA-4 (?4?1 Integrin)-Mediated Cell Adhesion Based on the Ile-Leu-Asp-Val Tetrapeptide

Autor: Anand S. Dutta, Amanda Rees, Alec Jamieson, Duncan Haworth, Rod S. Kittlety, Lorraine A. Hassall, Paul Gellert, James J. Gormley, Christopher F. Reilly, Peter J. Alcock, Christopher F. Hayward, Linda J. Wood, Mandy L. Crowther, Julie M. Moores

Publikováno v: Journal of Peptide Science. 6:321-341

Potent monomeric and dimeric cyclic peptide very late antigen-4 (VLA-4) inhibitors have been designed based on a tetrapeptide (Ile-Leu-Asp-Val) sequence present in a 25-amino acid peptide (CS-1) reported in the literature. The peptides, synthesized b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25ceb93494fef4de3a60f6b947f394cc
https://doi.org/10.1002/1099-1387(200007)6:7<321::aid-psc259>3.0.co

Zobrazit plný text záznamu

Purification and characterization of endogenous peptides extracted from HLA-DR isolated from the spleen of a patient with rheumatoid arthritis

Autor: Robert D. Gordon, Janice A. Young, Stephen Rayner, Richard W. A. Luke, Mandy L. Crowther, Paul Wordsworth, John Bell, Giles Hassall, Jonathan Evans, Sue A. Hinchliffe, Eric J. Culbert, Matthew D. Davison

Publikováno v: European journal of immunology. 25(5)

We have purified HLA-DR from the spleen of a patient with rheumatoid arthritis. The patient had Felty's syndrome and was heterozygous for the DR4Dw4 antigen. We have isolated endogenous peptides from purified HLA-DR molecules. The peptides were purif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8df08e038b7c7ded43ae436378befd
http://ora.ox.ac.uk/objects/uuid:f0a16002-f349-46aa-b47a-5d175a1b75d0

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání