Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mandy J Croyle"'
Autor:
Sarah J. Miller, Nancy M. Gonzalez, Morgan E. Smith, Mandy J. Croyle, Bradley K. Yoder, Kurt A. Zimmerman
Publikováno v:
Physiological Reports, Vol 12, Iss 22, Pp n/a-n/a (2024)
Abstract Intraflagellar transport protein 88 (Ift88) is required for the formation of cilia in the thymus and non‐ciliary dependent functions including T cell immune synapse formation. To test the role of Ift88 in T cell development, we performed f
Externí odkaz:
https://doaj.org/article/5863536cb3ac4d7188e02c1f17ea7552
Autor:
Nicolas F Berbari, Erik B Malarkey, S M Zaki R Yazdi, Andrew D McNair, Jordyn M Kippe, Mandy J Croyle, Timothy W Kraft, Bradley K Yoder
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106576 (2014)
It has been known for decades that neurons throughout the brain possess solitary, immotile, microtubule based appendages called primary cilia. Only recently have studies tried to address the functions of these cilia and our current understanding rema
Externí odkaz:
https://doaj.org/article/2e71e71e05b6427483f04e4886628a6e
Autor:
Zhang Li, Kurt A. Zimmerman, Sreelakshmi Cherakara, Phillip H. Chumley, James F. Collawn, Jun Wang, Courtney J. Haycraft, Cheng J. Song, Teresa Chacana, Reagan S. Andersen, Mandy J. Croyle, Ernald J. Aloria, Raksha P. Hombal, Isis N. Thomas, Hanan Chweih, Kristin L. Simanyi, James F. George, John M. Parant, Michal Mrug, Bradley K. Yoder
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/d33111929bb3477fae3f2ddadac69a61
Autor:
Melissa R. Bentley-Ford, Reagan S. Andersen, Mandy J. Croyle, Courtney J. Haycraft, Kelsey R. Clearman, Jeremy B. Foote, Jeremy F. Reiter, Bradley K. Yoder
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Atxn10 is a gene known for its role in cytokinesis and is associated with spinocerebellar ataxia (SCA10), a slowly progressing cerebellar syndrome caused by an intragenic pentanucleotide repeat expansion. Atxn10 is also implicated in the ciliopathy s
Externí odkaz:
https://doaj.org/article/9d7d5542e32b4071b4aa9da8b86dd96c
Autor:
Zhang Li, Zhengqin Yang, Jeremie M. Lever, Kurt A. Zimmerman, Bradley K. Yoder, Mandy J. Croyle, James F. George, Anupam Agarwal
Publikováno v:
Am J Physiol Renal Physiol
Kidney resident macrophages (KRMs) are involved in maintaining renal homeostasis and in controlling the pathological outcome of acute kidney injury and cystic kidney disease in mice. In adult mice, KRMs maintain their population through self-renewal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7542d2673072d2e63ae160489016fb80
https://doi.org/10.1152/ajprenal.00129.2021
https://doi.org/10.1152/ajprenal.00129.2021
Autor:
Zhang, Li, Kurt A, Zimmerman, Sreelakshmi, Cherakara, Phillip, Chumley, James F, Collawn, Jun, Wang, Courtney J, Haycraft, Cheng J, Song, Teresa, Chacana, Reagan S, Andersen, Mandy J, Croyle, Ernald J, Aloria, Raksha P, Hombal, Isis N, Thomas, Hanan, Chweih, Kristin L, Simanyi, James F, George, John M, Parant, Michal, Mrug, Bradley K, Yoder
Publikováno v:
Disease modelsmechanisms.
Although renal macrophages have been shown to contribute to cystic kidney disease in PKD animal models, it remains unclear if there is a specific macrophage subpopulation involved. Here we analyze changes in macrophage populations during renal matura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e51519d9aa52e146d5ab89ff523e80cb
https://pubmed.ncbi.nlm.nih.gov/36457161
https://pubmed.ncbi.nlm.nih.gov/36457161
Autor:
Kurt A. Zimmerman, Zhang Li, Michal Mrug, Ernald Jules G. Aloria, Cheng Jack Song, Bradley K. Yoder, Mandy J. Croyle
Publikováno v:
Kidney360. 2:989-995
Key Points Ly6chi infiltrating macrophage numbers are increased in injured, conditional Ift88 mice, compared with controls. Loss of Ly6chi infiltrating macrophages slows injury-accelerated cystic disease. Ly6chi infiltrating macrophages drive cystic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c320092f563b39189058d682c41d367d
https://doi.org/10.34067/kid.0000882021
https://doi.org/10.34067/kid.0000882021
Autor:
Courtney J. Haycraft, Kathryn M Brewer, Devan M Rockwell, Melissa R Bentley-Ford, Amber K. O'Connor, Mandy J. Croyle, Nicolas F. Berbari, Bradley K. Yoder, Robert A. Kesterson
Publikováno v:
Dev Dyn
BACKGROUND: Genetic tools to study gene function and the fate of cells in the anterior limb bud are very limited. RESULTS: We describe a transgenic mouse line expressing CreER(T2) from the Aristaless-like 4 (Alx4) promoter that induces recombination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dc232b940e9a5e14eae25ee9f31728
https://doi.org/10.1002/dvdy.328
https://doi.org/10.1002/dvdy.328
Autor:
Mandy J. Croyle, Reagan S Andersen, Nicolas F. Berbari, Staci E. Engle, Addison Rains, Kelsey R. Clearman, Bradley K. Yoder, Melissa R Bentley-Ford, Courtney J. Haycraft
Publikováno v:
Hum Mol Genet
Primary cilia are critical sensory and signaling compartments present on most mammalian cell types. These specialized structures require a unique signaling protein composition relative to the rest of the cell to carry out their functions. Defects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f3b25c27754d3a292a6e79d6dd4b1a
https://doi.org/10.1093/hmg/ddab039
https://doi.org/10.1093/hmg/ddab039
Autor:
Courtney J. Haycraft, Mandy J. Croyle, Reagan S Andersen, Cameron LaFayette, Mikyla Scott, Bradley K. Yoder, Melissa R Bentley-Ford, Melissa LaBonty, Holly R. Thomas, John M. Parant
Publikováno v:
Genetics
Primary cilia are sensory and signaling hubs with a protein composition that is distinct from the rest of the cell due to the barrier function of the transition zone (TZ) at the base of the cilium. Protein transport across the TZ is mediated in part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d5e05abaa017ea965f8dcbb7b86d06
https://europepmc.org/articles/PMC8733634/
https://europepmc.org/articles/PMC8733634/
