Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mandy I. Cheng"'
Autor:
Mandy I. Cheng, Joey H. Li, Luke Riggan, Bryan Chen, Rana Yakhshi Tafti, Scott Chin, Feiyang Ma, Matteo Pellegrini, Haley Hrncir, Arthur P. Arnold, Timothy E. O’Sullivan, Maureen A. Su
Publikováno v:
Nature Immunology. 24:780-791
Autor:
Brittney N Nguyen, Alfredo Chávez-Arroyo, Mandy I Cheng, Maria Krasilnikov, Alexander Louie, Daniel A Portnoy
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008622 (2020)
Listeria monocytogenes is a facultative intracellular bacterial pathogen that escapes from phagosomes and induces a robust adaptive immune response in mice, while mutants unable to escape phagosomes fail to induce a robust adaptive immune response an
Externí odkaz:
https://doaj.org/article/2c235378adc84da6a9b35bf247455084
Autor:
Mandy I. Cheng, Luke Riggan, Joey H. Li, Rana Yakhshi Tafti, Scott Chin, Feiyang Ma, Matteo Pellegrini, Haley Hrncir, Arthur P. Arnold, Timothy E. O’Sullivan, Maureen A. Su
Viral infection outcomes are sex-biased, with males generally more susceptible than females. Paradoxically, the numbers of anti-viral natural killer (NK) cells are increased in males compared to females. Using samples from mice and humans, we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dfc5d04a50e0fd6655bccd33eaa85ee
https://doi.org/10.1101/2022.04.21.489076
https://doi.org/10.1101/2022.04.21.489076
Autor:
Melissa G. Lechner, Anushi Y. Patel, Willy Hugo, Trevor E. Angell, Mandy I. Cheng, Marissa S. Pioso, Aline T. Hoang, Natalie Yakobian, Ethan C. McCarthy, Ho-Chung Chen, Eduardo D. Rodriguez, Lily Guo, Michael Astourian, Alexandra Drakaki, Pouyan Famini, Antoni Ribas, Maureen A. Su
Checkpoint inhibitor (ICI) immunotherapy leverages the body’s own immune system to attack cancer cells but leads to unwanted autoimmune side effects in up to 60% of patients. Such immune related adverse events (IrAE) may lead to treatment interrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc5dd018620224cf8c8d8463725d292
https://doi.org/10.1101/2022.01.19.476844
https://doi.org/10.1101/2022.01.19.476844
Autor:
Yan Wang, Lily Guo, Xihui Yin, Ethan C. McCarthy, Mandy I. Cheng, Aline T. Hoang, Ho-Chung Chen, Anushi Y. Patel, Denise Allard Trout, Erin Xu, Natalie Yakobian, Willy Hugo, James F. Howard, Katherine M. Sheu, Alexander Hoffmann, Melissa G. Lechner, Maureen A. Su
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 4
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance GBS and CIDP are autoimmune disorders of the PNS that can be debilitating and even life threatening. Current therapies, which include corticosteroids and intravenous gammaglobulin, have poorly defined mechanisms of action and are ineffec
Autor:
Mandy I Cheng, Luke Riggan, Feiyang Ma, Scott Chin, Rana Tafti, Matteo Pellegrini, Timothy E. O’Sullivan, Maureen A. Su
Publikováno v:
The Journal of Immunology. 208:165.07-165.07
Natural killer (NK) cells are circulating type 1 innate lymphocytes that protect against viral infection and cancer. While it is now clear that NK cells display distinct epigenetic states during development and activation, the factors that control th
Publikováno v:
JCI insight, vol 5, iss 3
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease of the peripheral nerves that presents with either chronic progression or relapsing disease. Recent studies in samples from patients with CIDP and mouse models have del
Autor:
Mandy I. Cheng, Alfredo Chávez-Arroyo, Maria Krasilnikov, Daniel A. Portnoy, Alexander Louie, Brittney N. Nguyen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008622 (2020)
PLoS Pathogens
PLoS Pathogens
Listeria monocytogenes is a facultative intracellular bacterial pathogen that escapes from phagosomes and induces a robust adaptive immune response in mice, while mutants unable to escape phagosomes fail to induce a robust adaptive immune response an
Publikováno v:
Cellular microbiology, vol 20, iss 9
Cheng, MI; Chen, C; Engström, P; Portnoy, DA; & Mitchell, G. (2018). Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol. Cellular Microbiology, 20(9). doi: 10.1111/cmi.12854. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2wn0d4r0
Cheng, MI; Chen, C; Engström, P; Portnoy, DA; & Mitchell, G. (2018). Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol. Cellular Microbiology, 20(9). doi: 10.1111/cmi.12854. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2wn0d4r0
© 2018 John Wiley & Sons Ltd Listeria monocytogenes grows in the host cytosol and uses the surface protein ActA to promote actin polymerisation and mediate actin-based motility. ActA, along with two secreted bacterial phospholipases C, also mediates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2ec040c8906de821f7df1fce6833f3
https://escholarship.org/uc/item/2wn0d4r0
https://escholarship.org/uc/item/2wn0d4r0
Autor:
Daniel A. Portnoy, Gabriel Mitchell, Kent L. McDonald, Mandy I. Cheng, Aaron T. Whiteley, Sara Kianian, Brittney N. Nguyen, Chen Chen, Douglas R. Green, Jeffery S. Cox
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 2
Xenophagy is a selective macroautophagic process that protects the host cytosol by entrapping and delivering microbes to a degradative compartment. Both noncanonical autophagic pathways and xenophagy are activated by microbes during infection, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6238e11caf0e4809c30778c9a2ae3952
https://europepmc.org/articles/PMC5777066/
https://europepmc.org/articles/PMC5777066/