Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mandy Glass"'
Autor:
Anirban Sanyal, Nina Wallaschek, Mandy Glass, Louis Flamand, Darren J. Wight, Benedikt B. Kaufer
Publikováno v:
Viruses, Vol 10, Iss 8, p 401 (2018)
Human herpesvirus 6A (HHV-6A) replicates in peripheral blood mononuclear cells (PBMCs) and various T-cell lines in vitro. Intriguingly, the virus can also establish latency in these cells, but it remains unknown what influences the decision between l
Externí odkaz:
https://doaj.org/article/b66b522a63f04f5d9dd4358bd1da54f8
Autor:
Elizabeth Sloan, Michael H Tatham, Marine Groslambert, Mandy Glass, Anne Orr, Ronald T Hay, Roger D Everett
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005059 (2015)
Covalent linkage to members of the small ubiquitin-like (SUMO) family of proteins is an important mechanism by which the functions of many cellular proteins are regulated. Sumoylation has roles in the control of protein stability, activity and locali
Externí odkaz:
https://doaj.org/article/36e91925e46349f6badef79650c00cd6
Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host.
Autor:
Mariana Varela, Esther Schnettler, Marco Caporale, Claudio Murgia, Gerald Barry, Melanie McFarlane, Eva McGregor, Ilaria M Piras, Andrew Shaw, Catherine Lamm, Anna Janowicz, Martin Beer, Mandy Glass, Vanessa Herder, Kerstin Hahn, Wolfgang Baumgärtner, Alain Kohl, Massimo Palmarini
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003133 (2013)
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals. Since its discovery in November 2011, SBV has spread very rapidly to many European countries
Externí odkaz:
https://doaj.org/article/f882b13f54e84b6c98a158249caa2c54
Autor:
Chris Boutell, Delphine Cuchet-Lourenço, Emilia Vanni, Anne Orr, Mandy Glass, Steven McFarlane, Roger D Everett
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002245 (2011)
Intrinsic antiviral resistance represents the first line of intracellular defence against virus infection. During herpes simplex virus type-1 (HSV-1) infection this response can lead to the repression of viral gene expression but is counteracted by t
Externí odkaz:
https://doaj.org/article/51ccf9fc5dae467c83805b22859b0132
Autor:
Martina Dezeljin, Rudolf Bauerfeind, Anne Binz, Mandy Glaß, Kirsten A. Keyser, Corinna Templin, Luka Cicin-Sain, Ivana Kutle, Beate Sodeik, Sarah Sengstake, Tobias Kubsch, Martin Messerle
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Cell rounding is a hallmark of the cytopathic effect induced by cytomegaloviruses. By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutant was identified that did not elicit cell rounding and lacked the ability to form typic
Publikováno v:
The Journal of general virology. 98(7)
Human cytomegalovirus (HCMV) is a ubiquitous betaherpesvirus that causes life-threatening disease in immunocompromised and immunonaive individuals. Type I interferons (IFNs) are crucial molecules in the innate immune response to HCMV and are also kno
Autor:
Taranjit Singh, Rai, Mandy, Glass, John J, Cole, Mohammad I, Rather, Morgan, Marsden, Matthew, Neilson, Claire, Brock, Ian R, Humphreys, Roger D, Everett, Peter D, Adams
Publikováno v:
Nucleic Acids Research
The HIRA histone chaperone complex deposits histone H3.3 into nucleosomes in a DNA replication- and sequence-independent manner. As herpesvirus genomes enter the nucleus as naked DNA, we asked whether the HIRA chaperone complex affects herpesvirus in
Autor:
Roger D. Everett, Mandy Glass
Publikováno v:
Journal of Virology. 87:2174-2185
Upon the entry of the viral genome into the nucleus, herpes simplex virus type 1 (HSV-1) gene expression is rapidly repressed by constitutively expressed cellular proteins. This intrinsic antiviral defense is normally counteracted by ICP0, which allo
Publikováno v:
Journal of Virology. 86:11209-11222
Herpes simplex virus 1 (HSV-1) immediate-early protein ICP0 localizes to cellular structures known as promyelocytic leukemia protein (PML) nuclear bodies or ND10 and disrupts their integrity by inducing the degradation of PML. There are six PML isofo
Autor:
Mandy Glass, Tanja Strive, Beate Sodeik, Anne Binz, Rudolf Bauerfeind, Katinka Döhner, Kathrin Rode
Publikováno v:
Journal of Virology. 85:4271-4283
Incoming capsids of herpes simplex virus type 1 (HSV-1) enter the cytosol by fusion of the viral envelopes with host cell membranes and use microtubules and microtubule motors for transport to the nucleus. Upon docking to the nuclear pores, capsids r