Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mandy E Turner"'
Autor:
Mandy E. Turner, Tyler S. Rowsell, Christine A. White, Martin Kaufmann, Patrick A. Norman, Kathryn Neville, Martin Petkovich, Glenville Jones, Michael A. Adams, Rachel M. Holden
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Chronic kidney disease (CKD) results in calcitriol deficiency and altered vitamin D metabolism. The objective of this study was to assess the 24-hydroxylation-mediated metabolism of 25(OH)D3 and 1,25(OH)2D3 in a cross-sectional analysis of p
Externí odkaz:
https://doaj.org/article/0924dd975e214be3af3f9fb607ba07a1
Autor:
Francesca Bartoli‐Leonard, Jonas Zimmer, Abhijeet R. Sonawane, Katelyn Perez, Mandy E. Turner, Shiori Kuraoka, Tan Pham, Feifei Li, Masanori Aikawa, Sasha Singh, Luke Brewster, Elena Aikawa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 6 (2023)
Background Peripheral arterial disease (PAD) is estimated to affect 7% of the adult population in the United States; however, there is currently little understanding of the key cellular and molecular pathways at play. With PAD characterized by vascul
Externí odkaz:
https://doaj.org/article/b348a4532e6d463a9c852bacf1b46798
Autor:
Francesca Bartoli-Leonard, Mandy E. Turner, Jonas Zimmer, Roland Chapurlat, Tan Pham, Masanori Aikawa, Aruna D. Pradhan, Pawel Szulc, Elena Aikawa
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 8, Pp 100242- (2022)
Elevated circulating lipoprotein (a) [Lp(a)] is associated with an increased risk of first and recurrent cardiovascular events; however, the effect of baseline Lp(a) levels on long-term outcomes in an elderly population is not well understood. The cu
Externí odkaz:
https://doaj.org/article/2b8442870e08470980d7a10b779f6a38
Autor:
Mandy E Turner, Amanda S Paynter, Christine A White, Tom Mazzetti, Emilie C Ward, Patrick A Norman, Jenny Munroe, Michael A Adams, Rachel M Holden
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:909-919
Context Dietary consumption of phosphate is increasing, and elevated serum phosphate is associated with increased cardiovascular disease (CVD) risk. Sex differences in phosphate homeostasis and response to changes in dietary phosphate intake, which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3d7584dfc7397875d8cc98f5f5d887
https://doi.org/10.1210/clinem/dgac616
https://doi.org/10.1210/clinem/dgac616
Publikováno v:
Immunological Reviews. 312:20-37
Extracellular vesicles (EVs) are critical in the initiation and progression of cardiovascular calcification, and immune cell infiltration and inflammation have a central role in this process. EVs egress from various cardiovascular cell types, which w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6881955718937e068030c7d48f0fc070
https://doi.org/10.1111/imr.13134
https://doi.org/10.1111/imr.13134
Publikováno v:
Immunological Reviews. 312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe8e52bf19e58091cdb86229fe09e57
https://doi.org/10.1111/imr.12873
https://doi.org/10.1111/imr.12873
Autor:
Sarah M. Taylor, Karen J. Rees-Milton, Christine A. White, Kathryn J. Neville, Michael A. Adams, Mandy E Turner, Tassos Anastassiades, Wilma M. Hopman, Rachel M. Holden
Publikováno v:
Calcified Tissue International. 108:354-363
The 24 kD form of secreted phosphoprotein (SPP-24), a cytokine-binding bone matrix protein with various truncated C-terminal products, is primarily synthesized by the liver. SPP-24 shares homology with fetuin-A, a potent vascular and soft tissue calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16136a3aac9faa9ed9e45608dc037709
https://doi.org/10.1007/s00223-020-00783-3
https://doi.org/10.1007/s00223-020-00783-3
Autor:
Rachel M Holden, Sarah L Booth, Deborah Zimmerman, Louise Moist, Patrick A Norman, Andrew G Day, Alex Menard, Xueyan Fu, M Kyla Shea, Corinne S Babiolakis, Robert Nolan, Mandy E Turner, Emilie Ward, Martin Kaufmann, Michael A Adams, Daren K Heyland
Publikováno v:
Nephrol Dial Transplant
Background Vitamin K activates matrix Gla protein (MGP), a key inhibitor of vascular calcification. There is a high prevalence of sub-clinical vitamin K deficiency in patients with end-stage kidney disease. Methods A parallel randomized placebo-contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3768f197218052991eadc5cb1ad3ef0a
https://pubmed.ncbi.nlm.nih.gov/35641194
https://pubmed.ncbi.nlm.nih.gov/35641194
Autor:
Mandy E, Turner, Tyler S, Rowsell, Martin, Kaufmann, Patrick A, Norman, Kathryn, Neville, Sam, Sarabia, Christine A, White, Martin, Petkovich, Glenville, Jones, Michael A, Adams, Rachel M, Holden
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 226
Calcitriol, and other vitamin D receptor activators, remain a primary treatment for elevated parathyroid hormone levels in patients with end stage kidney disease. The objective of this study was to assess the 24-hydroxylation-mediated metabolism of 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cda2f1d016066118f6dce678dc15a032
https://pubmed.ncbi.nlm.nih.gov/36374723
https://pubmed.ncbi.nlm.nih.gov/36374723
Autor:
Mandy E Turner, Tyler S Rowsell, Austin P Lansing, Paul S Jeronimo, Lok Hang Lee, Bruno A Svajger, Jason G E Zelt, Corey M Forster, Martin P Petkovich, Rachel M Holden, Michael A Adams
Publikováno v:
Cardiovascular research.
Aims Non-renal extravasation of phosphate from the circulation and transient accumulation into tissues and extracellular fluid is a regulated process of acute phosphate homeostasis that is not well understood. This process is especially relevant in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb584cd78718db74ddaec834f0690716
https://pubmed.ncbi.nlm.nih.gov/36190819
https://pubmed.ncbi.nlm.nih.gov/36190819