Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mandy Beyer"'
Autor:
Christian Marx, Jürgen Sonnemann, Oliver D. K. Maddocks, Lisa Marx-Blümel, Mandy Beyer, Doerte Hoelzer, René Thierbach, Claudia Maletzki, Michael Linnebacher, Thorsten Heinzel, Oliver H. Krämer
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Metabolic adaptations can allow cancer cells to survive DNA-damaging chemotherapy. This unmet clinical challenge is a potential vulnerability of cancer. Accordingly, there is an intense search for mechanisms that modulate cell met
Externí odkaz:
https://doaj.org/article/b54be1c1c57b4247a2dde92cec4134b4
Autor:
Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://doaj.org/article/0b74c48fb69942fab1d217753fe500f2
Autor:
Mandy Beyer, Oliver H. Krämer
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101512- (2022)
Summary: Genetic silencing of leukemia-associated proteins with small interfering RNAs (siRNAs) is a straightforward way to delineate their functions. It can be very challenging to deliver siRNAs to leukemia-derived cells with high transfection effic
Externí odkaz:
https://doaj.org/article/185e63dcb09b4d06844bdfd73fb41ae1
Autor:
Andreas D Hofmann, Mandy Beyer, Udo Krause-Buchholz, Manja Wobus, Martin Bornhäuser, Gerhard Rödel
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35160 (2012)
Mitochondria are essential organelles with multiple functions, especially in energy metabolism. Recently, an increasing number of data has highlighted the role of mitochondria for cellular differentiation processes. Metabolic differences between stem
Externí odkaz:
https://doaj.org/article/f883562443ea44d3a33dcbda95c40a50
Autor:
Miriam Pons, Mandy Beyer
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0e27358386809fd29236afd82e2bf4
https://doi.org/10.1007/978-1-0716-2788-4_2
https://doi.org/10.1007/978-1-0716-2788-4_2
Autor:
Miriam, Pons, Mandy, Beyer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2589
One of the main characteristics of cancer is the rapid proliferation of transformed cells. Cancer therapies aim to kill such cells. Cancer clones surviving therapy can be resistant to the treatment, but they can also lose the ability to proliferate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::911ab0b06755b2d5d4c195ec849127d2
https://pubmed.ncbi.nlm.nih.gov/36255615
https://pubmed.ncbi.nlm.nih.gov/36255615
Autor:
Vanessa Wachholz, Teodora Nikolova, Siavosh Mahboobi, Mandy Beyer, Al-Hassan M. Mustafa, Andreas Sellmer, Melanie Dzulko, Walburgis Brenner, Thomas Kindler, Christina Brachetti, Oliver H. Krämer, Sven J. Henninger, Andrea Piee-Staffa, Patricia Haehnel, Yanira Zeyn
Publikováno v:
Archives of Toxicology
Acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase (FLT3) is a clinically unresolved problem. AML cells frequently have a dysregulated expression and activity of epigenetic modulators of the histone deacetylase (HDAC) family.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6e9c9334528e64c13e6fea58283b75
Autor:
Michael Linnebacher, Mandy Beyer, Sergio Lilla, Christina S Mullins, Irene Hauzenberger, Kanstantsin Siniuk, Suneetha Nunna, Juergen Sonnemann, Martin Westermann, Christian Marx, Thorsten Heinzel, Oliver D. K. Maddocks, Oliver H. Kraemer, Andrea Piee-Staffa, Francesco Neri, Lisa Marx-Bluemel, René Thierbach, Said Kdimati, Zhao-Qi Wang, Tobias Wagner, Felix B. Meyer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3431d40d016840c1d0e24efef640c7
https://doi.org/10.1002/1878-0261.13060/v2/response1
https://doi.org/10.1002/1878-0261.13060/v2/response1
Autor:
Wolfgang Sippl, Oliver H. Krämer, Sven J. Henninger, Markus Christmann, Thomas Kindler, Mandy Beyer, Siavosh Mahboobi, Al-Hassan M. Mustafa, Bastian Schubert, Andreas Sellmer, Patricia S. Haehnel, Ece Gurdal, Sebastian Drube
Publikováno v:
Cell Chemical Biology. 29:398-411.e4
Internal tandem duplications (ITDs) in the FMS-like tyrosine kinase-3 (FLT3) are causally linked to acute myeloid leukemia (AML) with poor prognosis. Available FLT3 inhibitors (FLT3i) preferentially target inactive or active conformations of FLT3. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150050db68bbe6766062daba39066958
https://doi.org/10.1016/j.chembiol.2021.10.011
https://doi.org/10.1016/j.chembiol.2021.10.011