Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mandy, Sibson"'
Autor:
Richard Saffery, Stephan Beck, Thierry Fournier, Ursula Manuelpillai, Ruth Morley, D. Evain-Brion, Thomas A. Down, Vardhman K. Rakyan, Hong Kiat Ng, Eva Dimitriadis, Jeffrey M. Craig, Mandy Sibson, Boris Novakovic
Publikováno v:
Journal of Biological Chemistry. 284:14838-14848
Plasma concentrations of biologically active vitamin D (1,25-(OH)2D) are tightly controlled via feedback regulation of renal 1α-hydroxylase (CYP27B1; positive) and 24-hydroxylase (CYP24A1; catabolic) enzymes. In pregnancy, this regulation is uncoupl
Publikováno v:
Genome Research. 11:448-457
Centromere protein A (CENP-A) is an essential histone H3-related protein that constitutes the specialized chromatin of an active centromere. It has been suggested that this protein plays a key role in the epigenetic marking and transformation of nonc
Autor:
Stefan Hiendleder, Ursula Manuelpillai, Vardhman K. Rakyan, Stephan Beck, Ruth Morley, Mandy Sibson, Hong-Kiat Ng, Nicholas C. Wong, Richard Saffery, Thomas A. Down, Boris Novakovic, Claire T. Roberts, Jeffrey M. Craig
Publikováno v:
The Journal of Biological Chemistry
The genome of extraembryonic tissue, such as the placenta, is hypomethylated relative to that in somatic tissues. However, the origin and role of this hypomethylation remains unclear. The DNA methyltransferases DNMT1, -3A, and -3B are the primary med
Autor:
Boris, Novakovic, Mandy, Sibson, Hong Kiat, Ng, Ursula, Manuelpillai, Vardhman, Rakyan, Thomas, Down, Stephan, Beck, Thierry, Fournier, Danielle, Evain-Brion, Eva, Dimitriadis, Jeffrey M, Craig, Ruth, Morley, Richard, Saffery
Publikováno v:
The Journal of Biological Chemistry
Plasma concentrations of biologically active vitamin D (1,25-(OH)(2)D) are tightly controlled via feedback regulation of renal 1alpha-hydroxylase (CYP27B1; positive) and 24-hydroxylase (CYP24A1; catabolic) enzymes. In pregnancy, this regulation is un
Autor:
Jeffrey M. Craig, Richard Saffery, C. Dewi, Finlay A. Macrae, Roberta Andronikos, Nicholas C. Wong, B. Weinrich, Mark D. Pertile, Mandy Sibson, Boris Novakovic, Ruth Morley
Publikováno v:
Cancer letters. 268(1)
Methylation of the human APC gene promoter is associated with several different types of cancers and has also been documented in some pre-cancerous tissues. We have examined the methylation of APC gene promoters in human placenta and choriocarcinoma
Publikováno v:
Genome research. 13(7)
Human neocentromeres are fully functional centromeres that arise at previously noncentromeric regions of the genome. We have tested a rapid procedure of genomic array analysis of chromosome scaffold/matrix attachment regions (S/MARs), involving the i