Zobrazeno 1 - 10 of 378 pro vyhledávání: '"Mandikian, D."'
1
Akademický článek
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy.
Autor: Adhikari P; Genentech Inc., South San Francisco, California 94080, United States., Li G; Genentech Inc., South San Francisco, California 94080, United States., Go M; Genentech Inc., South San Francisco, California 94080, United States., Mandikian D; Genentech Inc., South San Francisco, California 94080, United States., Rafidi H; Genentech Inc., South San Francisco, California 94080, United States., Ng C; Genentech Inc., South San Francisco, California 94080, United States., Anifa S; Genentech Inc., South San Francisco, California 94080, United States., Johnson K; Genentech Inc., South San Francisco, California 94080, United States., Bao L; Genentech Inc., South San Francisco, California 94080, United States., Hernandez Barry H; Genentech Inc., South San Francisco, California 94080, United States., Rowntree R; Genentech Inc., South San Francisco, California 94080, United States., Agard N; Genentech Inc., South San Francisco, California 94080, United States., Wu C; Genentech Inc., South San Francisco, California 94080, United States., Chou KJ; Genentech Inc., South San Francisco, California 94080, United States., Zhang D; Genentech Inc., South San Francisco, California 94080, United States., Kozak KR; Genentech Inc., South San Francisco, California 94080, United States., Pillow TH; Genentech Inc., South San Francisco, California 94080, United States., Lewis GD; Genentech Inc., South San Francisco, California 94080, United States., Yu SF; Genentech Inc., South San Francisco, California 94080, United States., Boswell CA; Genentech Inc., South San Francisco, California 94080, United States., Sadowsky JD; Genentech Inc., South San Francisco, California 94080, United States.
Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2024 Jul 17; Vol. 146 (28), pp. 19088-19100. Date of Electronic Publication: 2024 Jul 01.
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2
Akademický článek
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration.
Autor: Ramos MK; Genentech, Inc., One DNA Way, South San Francisco, California., Mandikian D; Genentech, Inc., One DNA Way, South San Francisco, California., Sermeño LN; Genentech, Inc., One DNA Way, South San Francisco, California., King A; Genentech, Inc., One DNA Way, South San Francisco, California., Dent AT; Genentech, Inc., One DNA Way, South San Francisco, California., Ho J; Genentech, Inc., One DNA Way, South San Francisco, California., Ulufatu S; Genentech, Inc., One DNA Way, South San Francisco, California., Lombana TN; Genentech, Inc., One DNA Way, South San Francisco, California., Spiess C; Genentech, Inc., One DNA Way, South San Francisco, California., Go MAT; Genentech, Inc., One DNA Way, South San Francisco, California., Yu SF; Genentech, Inc., One DNA Way, South San Francisco, California., Kamath AV; Genentech, Inc., One DNA Way, South San Francisco, California., Ferl GZ; Genentech, Inc., One DNA Way, South San Francisco, California. boswell.andy@gene.com ferl.gregory@gene.com., Boswell CA; Genentech, Inc., One DNA Way, South San Francisco, California. boswell.andy@gene.com ferl.gregory@gene.com.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Oct; Vol. 20 (10), pp. 1956-1965. Date of Electronic Publication: 2021 Jul 12.
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3
Akademický článek
Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer.
Autor: Lo AA; Genentech Inc., South San Francisco, California., Johnston J; Genentech Inc., South San Francisco, California., Li J; Genentech Inc., South San Francisco, California., Mandikian D; Genentech Inc., South San Francisco, California., Hristopoulos M; Genentech Inc., South San Francisco, California., Clark R; Genentech Inc., South San Francisco, California., Nickles D; Genentech Inc., South San Francisco, California., Liang WC; Genentech Inc., South San Francisco, California., Hötzel K; Genentech Inc., South San Francisco, California., Dunlap D; Genentech Inc., South San Francisco, California., Pham T; Genentech Inc., South San Francisco, California., Cai H; Genentech Inc., South San Francisco, California., Ovacik M; Genentech Inc., South San Francisco, California., Bravo-Perez D; Genentech Inc., South San Francisco, California., Mai E; Genentech Inc., South San Francisco, California., Slaga D; Genentech Inc., South San Francisco, California., Ellerman D; Genentech Inc., South San Francisco, California., Ziai J; Genentech Inc., South San Francisco, California., Totpal K; Genentech Inc., South San Francisco, California., Lee G; Genentech Inc., South San Francisco, California., Boswell CA; Genentech Inc., South San Francisco, California., Payandeh J; Genentech Inc., South San Francisco, California., Wu Y; Genentech Inc., South San Francisco, California., Junttila TT; Genentech Inc., South San Francisco, California. junttila.teemu@gene.com.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Apr; Vol. 20 (4), pp. 716-725. Date of Electronic Publication: 2021 Feb 03.
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4
Akademický článek
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics.
Autor: Rafidi H; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California., Estevez A; Structural Biology, Genentech, Inc., South San Francisco, California., Ferl GZ; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California.; Biomedical Imaging, Genentech, Inc., South San Francisco, California., Mandikian D; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California., Stainton S; Safety Assessment, Genentech, Inc., South San Francisco, California., Sermeño L; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California., Williams SP; Antibody Engineering, Genentech, Inc., South San Francisco, California., Kamath AV; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California., Koerber JT; Antibody Engineering, Genentech, Inc., South San Francisco, California.; Research and Early Development, Genentech, Inc., South San Francisco, California., Boswell CA; Departments of Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech, Inc., South San Francisco, California. boswell.andy@gene.com.; Biomedical Imaging, Genentech, Inc., South San Francisco, California.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Oct; Vol. 20 (10), pp. 2008-2015. Date of Electronic Publication: 2021 Jul 26.
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5
Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability
Autor: Speca, DJ, Ogata, G, Mandikian, D, Bishop, HI, Wiler, SW, Eum, K, Wenzel, HJ, Doisy, ET, Matt, L, Campi, KL, Golub, MS, Nerbonne, JM, Hell, JW, Trainor, BC, Sack, JT, Schwartzkroin, PA, Trimmer, JS
Publikováno v: Genes, brain, and behavior, vol 13, iss 4
Speca, DJ; Ogata, G; Mandikian, D; Bishop, HI; Wiler, SW; Eum, K; et al.(2014). Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability. Genes, Brain and Behavior, 13(4), 394-408. doi: 10.1111/gbb.12120. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7j75t5d2
The Kv2.1 delayed rectifier potassium channel exhibits high-level expression in both principal and inhibitory neurons throughout the central nervous system, including prominent expression in hippocampal neurons. Studies of in vitro preparations sugge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e8547ddf9719a91ec6abf0b137dea9ed
https://escholarship.org/uc/item/7j75t5d2
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6
Akademický článek
Local depletion of large molecule drugs due to target binding in tissue interstitial space.
Autor: Zasedateleva, Tatiana1 (AUTHOR), Schaller, Stephan1 (AUTHOR), de Lange, Elizabeth C. M.2 (AUTHOR), de Witte, Wilhelmus E. A.1 (AUTHOR) wilbert.dewitte@esqlabs.com
Publikováno v: CPT: Pharmacometrics & Systems Pharmacology. Dec2024, Vol. 13 Issue 12, p2068-2086. 19p.
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7
Akademický článek
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response.
Autor: Dela Cruz Chuh J; Departments of Biochemical and Cellular Pharmacology, Genentech Inc , South San Francisco, CA, USA., Go M; Research biology, Genentech Inc , South San Francisco, CA, USA., Chen Y; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Guo J; Research biology, Genentech Inc , South San Francisco, CA, USA., Rafidi H; Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc , South San Francisco, CA, USA., Mandikian D; Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc , South San Francisco, CA, USA., Sun Y; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Lin Z; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Schneider K; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Zhang P; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Vij R; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Sharpnack D; Departments of Biochemical and Cellular Pharmacology, Genentech Inc , South San Francisco, CA, USA., Chan P; Departments of Biochemical and Cellular Pharmacology, Genentech Inc , South San Francisco, CA, USA., de la Cruz C; Research biology, Genentech Inc , South San Francisco, CA, USA., Sadowsky J; Protein Chemistry, Genentech Inc , South San Francisco, CA, USA., Seshasayee D; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Koerber JT; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA., Pillow TH; Discovery Chemistry, Genentech Inc , South San Francisco, CA, USA., Phillips GD; Research biology, Genentech Inc , South San Francisco, CA, USA., Rowntree RK; Research biology, Genentech Inc , South San Francisco, CA, USA., Boswell CA; Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc , South San Francisco, CA, USA., Kozak KR; Departments of Biochemical and Cellular Pharmacology, Genentech Inc , South San Francisco, CA, USA., Polson AG; Research biology, Genentech Inc , South San Francisco, CA, USA., Polakis P; Research biology, Genentech Inc , South San Francisco, CA, USA., Yu SF; Research biology, Genentech Inc , South San Francisco, CA, USA., Dragovich PS; Discovery Chemistry, Genentech Inc , South San Francisco, CA, USA., Agard NJ; Antibody Engineering, Genentech Inc , South San Francisco, CA, USA.
Publikováno v: MAbs [MAbs] 2021 Jan-Dec; Vol. 13 (1), pp. 1862452.
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8
Akademický článek
Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies.
Autor: Nazarova L; Preclinical and Translational Pharmacokinetics, Genentech Research and Early Development, South San Francisco, California., Rafidi H; Preclinical and Translational Pharmacokinetics, Genentech Research and Early Development, South San Francisco, California., Mandikian D; Preclinical and Translational Pharmacokinetics, Genentech Research and Early Development, South San Francisco, California., Ferl GZ; Preclinical and Translational Pharmacokinetics, Genentech Research and Early Development, South San Francisco, California.; Biomedical Imaging, Genentech Research and Early Development, South San Francisco, California., Koerber JT; Antibody Engineering, Genentech Research and Early Development, South San Francisco, California., Davies CW; Antibody Engineering, Genentech Research and Early Development, South San Francisco, California., Ulufatu S; In Vivo Studies, Genentech Research and Early Development, South San Francisco, California., Ho J; In Vivo Studies, Genentech Research and Early Development, South San Francisco, California., Lau J; Translational Oncology, Genentech Research and Early Development, South San Francisco, California., Yu SF; Translational Oncology, Genentech Research and Early Development, South San Francisco, California., Ernst J; Protein Chemistry, Genentech Research and Early Development, South San Francisco, California., Sadowsky JD; Protein Chemistry, Genentech Research and Early Development, South San Francisco, California., Boswell CA; Preclinical and Translational Pharmacokinetics, Genentech Research and Early Development, South San Francisco, California. boswell.andy@gene.com.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Apr; Vol. 19 (4), pp. 1052-1058. Date of Electronic Publication: 2020 Feb 05.
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9
Akademický článek
Compartmentalized signaling in the soma: Coordination of electrical and protein kinase A signaling at neuronal ER-plasma membrane junctions.
Autor: Vierra NC; School of Biological Sciences, University of Utah, Salt Lake City, Utah, USA.
Publikováno v: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2024 Nov; Vol. 46 (11), pp. e2400126. Date of Electronic Publication: 2024 Sep 13.
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10
Akademický článek
Hyaluronic Acid-Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics.
Autor: Famili A, Crowell SR, Loyet KM, Mandikian D, Boswell CA, Cain D, Chan J, Comps-Agrar L, Kamath A, Rajagopal K
Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2019 Nov 20; Vol. 30 (11), pp. 2782-2789. Date of Electronic Publication: 2019 Oct 11.
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